In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics.

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Main Authors: Ou, Yujia, Xie, Wen, Wang, Haoyu, Zheng, Yafeng, Guo, Zebin, Zheng, Baodong
Format: Artículo científico
Language:en
Published: International journal of biological macromolecules 2025
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author Ou, Yujia
Xie, Wen
Wang, Haoyu
Zheng, Yafeng
Guo, Zebin
Zheng, Baodong
author_facet Ou, Yujia
Xie, Wen
Wang, Haoyu
Zheng, Yafeng
Guo, Zebin
Zheng, Baodong
Ou, Yujia
Xie, Wen
Wang, Haoyu
Zheng, Yafeng
Guo, Zebin
Zheng, Baodong
collection PubMed - marine biology
contents In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome This study was to investigate the fundamental composition and structure, hypoglycemic activity and fermentation characteristics of Porphyra haitanensis glycoprotein (PG) following in vitro simulate gastrointestinal digestion. After in vitro digestion, PG was degraded into peptides, amino acids, and reducing sugars, and the digested PG structure evolved into functional aggregates that were more favorable for regulating intestinal flora. Such aggregated structure might inhibit the accessibility of digestive enzymes and significantly enhanced its hypoglycemic activity. Compared with undigested PG, the inhibition rate of digested PG on α-amylase and α-glucosidase was increased by 4.70 % and 7.69 %, respectively (P
format Artículo científico
id pubmed_39672441
institution PubMed
language en
publishDate 2025
publisher International journal of biological macromolecules
record_format pubmed
spellingShingle In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics.
Ou, Yujia
Xie, Wen
Wang, Haoyu
Zheng, Yafeng
Guo, Zebin
Zheng, Baodong
Glycoproteins
Fermentation
Porphyra
Hypoglycemic Agents
alpha-Amylases
Digestion
alpha-Glucosidases
Gastrointestinal Microbiome
In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome This study was to investigate the fundamental composition and structure, hypoglycemic activity and fermentation characteristics of Porphyra haitanensis glycoprotein (PG) following in vitro simulate gastrointestinal digestion. After in vitro digestion, PG was degraded into peptides, amino acids, and reducing sugars, and the digested PG structure evolved into functional aggregates that were more favorable for regulating intestinal flora. Such aggregated structure might inhibit the accessibility of digestive enzymes and significantly enhanced its hypoglycemic activity. Compared with undigested PG, the inhibition rate of digested PG on α-amylase and α-glucosidase was increased by 4.70 % and 7.69 %, respectively (P
title In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics.
topic Glycoproteins
Fermentation
Porphyra
Hypoglycemic Agents
alpha-Amylases
Digestion
alpha-Glucosidases
Gastrointestinal Microbiome
url https://pubmed.ncbi.nlm.nih.gov/39672441/