In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics.
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| Main Authors: | , , , , , |
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| Format: | Artículo científico |
| Language: | en |
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International journal of biological macromolecules
2025
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| _version_ | 1868266268235137026 |
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| author | Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong |
| author_facet | Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong |
| collection | PubMed - marine biology |
| contents | In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome This study was to investigate the fundamental composition and structure, hypoglycemic activity and fermentation characteristics of Porphyra haitanensis glycoprotein (PG) following in vitro simulate gastrointestinal digestion. After in vitro digestion, PG was degraded into peptides, amino acids, and reducing sugars, and the digested PG structure evolved into functional aggregates that were more favorable for regulating intestinal flora. Such aggregated structure might inhibit the accessibility of digestive enzymes and significantly enhanced its hypoglycemic activity. Compared with undigested PG, the inhibition rate of digested PG on α-amylase and α-glucosidase was increased by 4.70 % and 7.69 %, respectively (P |
| format | Artículo científico |
| id | pubmed_39672441 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | International journal of biological macromolecules |
| record_format | pubmed |
| spellingShingle | In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. Ou, Yujia Xie, Wen Wang, Haoyu Zheng, Yafeng Guo, Zebin Zheng, Baodong Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome This study was to investigate the fundamental composition and structure, hypoglycemic activity and fermentation characteristics of Porphyra haitanensis glycoprotein (PG) following in vitro simulate gastrointestinal digestion. After in vitro digestion, PG was degraded into peptides, amino acids, and reducing sugars, and the digested PG structure evolved into functional aggregates that were more favorable for regulating intestinal flora. Such aggregated structure might inhibit the accessibility of digestive enzymes and significantly enhanced its hypoglycemic activity. Compared with undigested PG, the inhibition rate of digested PG on α-amylase and α-glucosidase was increased by 4.70 % and 7.69 %, respectively (P |
| title | In vitro digestion of glycoproteins from Porphyra haitanensis: Effects on structure, hypoglycemic activity, and fermentation characteristics. |
| topic | Glycoproteins Fermentation Porphyra Hypoglycemic Agents alpha-Amylases Digestion alpha-Glucosidases Gastrointestinal Microbiome |
| url | https://pubmed.ncbi.nlm.nih.gov/39672441/ |