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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Tisseur, Lhana, Cojean, Sandrine, Gassama, Khadidiatou, Logé, Cédric, Pagniez, Fabrice, Cavé, Christian, Bernadat, Guillaume, Loiseau, Philippe M, Bach, Stéphane, Thiéfaine, Jérôme, Picot, Carine, Tomasoni, Christophe, Leclercq, Olivier, Baratte, Blandine, Robert, Thomas, Le Pape, Patrice, Rachidi, Najma, Bazin, Marc-Antoine, Marchand, Pascal
Format:	Artículo científico
Language:	en
Published:	ChemMedChem 2025
Subjects:	Casein Kinase I Antiprotozoal Agents Structure-Activity Relationship Pyrazines Leishmania donovani Protein Kinase Inhibitors Leishmania major Animals Molecular Structure Imidazoles Dose-Response Relationship, Drug Macrophages Parasitic Sensitivity Tests Humans Mice
Online Access:	Acceder al recurso
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