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| Main Authors: | , , , |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Organic & biomolecular chemistry
2025
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/39760490/ |
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Table of Contents:
- DMSO-promoted α-bromination of α-aryl ketones for the construction of 2-aryl-2-bromo-cycloketones. Zhai, Haojiang Li, Penghui Wang, Hongshuang Wang, Xiaohui A DMSO-promoted practical one-step α-bromination reaction of α-aryl ketones with NBS has been developed for the construction of 2-aryl-2-bromo-cycloketones. The desired regioselective α-bromination products were isolated in moderate to good yields, with a maximum tested scale of 15 mmol. Notably, ketamine derivatives could be smoothly synthesized in two steps.