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| Main Authors: | , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Fish & shellfish immunology
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/39793911/ |
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Table of Contents:
- Co-infection of nervous necrosis virus and Vibrio harveyi increased mortality and worsened the disease severity in the orange-spotted grouper (Epinephelus coioides). Guan, Lingfeng Li, Xinshuai Chen, Jinpeng Wang, Liqun Zhang, Xinyue Sun, Hongyan Li, Yanwei Yang, Min Qin, Qiwei Wang, Shaowen Animals Fish Diseases RNA Virus Infections Nodaviridae Vibrio Bass Coinfection Vibrio Infections Gene Expression Profiling Co-infections of different pathogenic microorganisms usually cause complex effects, and receive more attention. Red-grouper nervous necrosis virus (RGNNV) and Vibrio are the common viral and bacterial pathogens of fish, and are often detected simultaneously in diseased fish. However, the understanding of co-infection of RGNNV and Vibrio is still unclear. In this study, we have established a grouper (Epinephelus coioides) model of the co-infection of RGNNV and Vibrio harveyi (V. harveyi). Compared with single pathogen infection, co-infection of RGNNV and V. harveyi significantly caused more severe pathologic changes with higher mortality (P