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| Main Authors: | , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
International journal of biological macromolecules
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/39824414/ |
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| _version_ | 1868266255312486401 |
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| author | Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao |
| author_facet | Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao |
| collection | PubMed - marine biology |
| contents | Algae-derived polysaccharides and polysaccharide-based nanoparticles: A natural frontier in breast cancer therapy. Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao Humans Polysaccharides Breast Neoplasms Nanoparticles Female Antineoplastic Agents Animals Drug Delivery Systems Breast cancer is the second leading cause of cancer-related mortality among women worldwide, with its progression closely tied to the tumor microenvironment. To address the limitations and adverse effects of conventional therapies, algal polysaccharides and their nanoparticle derivatives have emerged as promising and effective anti-breast cancer agents. These bioactive compounds, derived from algae, are distinguished by their natural origin, non-toxicity, and significant medical relevance. Notably, algal polysaccharide-based nanoparticles exhibit advantageous properties such as hydrophilicity, biodegradability, prolonged circulation, and selective accumulation in tumor tissues. This review explores the relationship between the structural attributes of algal polysaccharides and their therapeutic efficacy. It further highlights the advantages of algal polysaccharide-based nanoparticles as drug delivery systems, particularly their potential in tumor targeting and overcoming multidrug resistance, thereby providing a theoretical foundation for their application in breast cancer treatment. |
| format | Artículo científico |
| id | pubmed_39824414 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | International journal of biological macromolecules |
| record_format | pubmed |
| spellingShingle | Algae-derived polysaccharides and polysaccharide-based nanoparticles: A natural frontier in breast cancer therapy. Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao Humans Polysaccharides Breast Neoplasms Nanoparticles Female Antineoplastic Agents Animals Drug Delivery Systems Algae-derived polysaccharides and polysaccharide-based nanoparticles: A natural frontier in breast cancer therapy. Cai, Jiaer Liao, Wei Wen, Jiahui Ye, Fangting Nie, Qing Chen, Weichao Zhao, Chao Humans Polysaccharides Breast Neoplasms Nanoparticles Female Antineoplastic Agents Animals Drug Delivery Systems Breast cancer is the second leading cause of cancer-related mortality among women worldwide, with its progression closely tied to the tumor microenvironment. To address the limitations and adverse effects of conventional therapies, algal polysaccharides and their nanoparticle derivatives have emerged as promising and effective anti-breast cancer agents. These bioactive compounds, derived from algae, are distinguished by their natural origin, non-toxicity, and significant medical relevance. Notably, algal polysaccharide-based nanoparticles exhibit advantageous properties such as hydrophilicity, biodegradability, prolonged circulation, and selective accumulation in tumor tissues. This review explores the relationship between the structural attributes of algal polysaccharides and their therapeutic efficacy. It further highlights the advantages of algal polysaccharide-based nanoparticles as drug delivery systems, particularly their potential in tumor targeting and overcoming multidrug resistance, thereby providing a theoretical foundation for their application in breast cancer treatment. |
| title | Algae-derived polysaccharides and polysaccharide-based nanoparticles: A natural frontier in breast cancer therapy. |
| topic | Humans Polysaccharides Breast Neoplasms Nanoparticles Female Antineoplastic Agents Animals Drug Delivery Systems |
| url | https://pubmed.ncbi.nlm.nih.gov/39824414/ |