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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Journal of dental sciences
2025
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| Accès en ligne: | https://pubmed.ncbi.nlm.nih.gov/39873094/ |
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| _version_ | 1868266249915465729 |
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| author | Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng |
| author_facet | Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng |
| collection | PubMed - marine biology |
| contents | Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells. Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng The extract of the soft coral has shown an anti-cancer activity in various cancer cells. However, its effect on the oral squamous cell carcinoma cell (OSCC) lines remains unclear. The purpose of this study is to investigate the anti-cancer effects of the extract of (C127) on the OSCC cells. This study evaluated the effects of the soft coral extract of (C127) on SAS and Ca9-22 cells, cell viability, migration ability, and apoptosis. Electric cell-substrate impedance sensing (ECIS) was parallelly used on SAS cells to confirm the results. C127 affected cell viability, morphology, and migration ability in both cell lines. In SAS cells, C127 inhibited cell viability in a dose dependent manner ( This study illustrated the potential of marine-derived compounds of on its activity against OSCC cells. |
| format | Artículo científico |
| id | pubmed_39873094 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Journal of dental sciences |
| record_format | pubmed |
| spellingShingle | Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells. Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells. Wang, Shih-Min Lu, Mei-Chin Hsu, Yu-Ming Huang, Chun-Chung Fang, Chih-Yuan Yu, Chuan-Hang Chueh, Pin Ju Yu, Cheng-Chia Lee, Shiao-Pieng The extract of the soft coral has shown an anti-cancer activity in various cancer cells. However, its effect on the oral squamous cell carcinoma cell (OSCC) lines remains unclear. The purpose of this study is to investigate the anti-cancer effects of the extract of (C127) on the OSCC cells. This study evaluated the effects of the soft coral extract of (C127) on SAS and Ca9-22 cells, cell viability, migration ability, and apoptosis. Electric cell-substrate impedance sensing (ECIS) was parallelly used on SAS cells to confirm the results. C127 affected cell viability, morphology, and migration ability in both cell lines. In SAS cells, C127 inhibited cell viability in a dose dependent manner ( This study illustrated the potential of marine-derived compounds of on its activity against OSCC cells. |
| title | Soft coral Lobophytum crassum extract inhibits migration and induces apoptosis capabilities in human oral squamous cell carcinoma cells. |
| url | https://pubmed.ncbi.nlm.nih.gov/39873094/ |