Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20.
Fuente:
PubMed
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Artículo científico |
| Sprache: | en |
| Veröffentlicht: |
Marine biotechnology (New York, N.Y.)
2025
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1868266247429292033 |
|---|---|
| author | Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong |
| author_facet | Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong |
| collection | PubMed - marine biology |
| contents | Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20. Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong Stramenopiles Transcriptome Lipid Metabolism Australia Fatty Acids Gene Expression Profiling Aurantiochytrium not only excels in producing long-chain polyunsaturated fatty acids such as docosahexaenoic acid for humans, but it is also a source of essential fatty acids with minimal impacts on wild fisheries and is vital in the transfer of atmospheric carbon to oceanic carbon sinks and cycles. This study aims to unveil the systems biology of lipid production in the Australian Aurantiochytrium sp. TC20 by comparing the transcriptomic profiles under optimal growth conditions with increased fatty acid production from the early (Day 1) to late exponential growth phase (Day 3). Particular attention was paid to 227 manually annotated genes involved in lipid metabolism, such as FAS (fatty acid synthetase) and subunits of polyunsaturated fatty acids (PUFA) synthase. PCA analysis showed that differentially expressed genes, related to lipid metabolism, efficiently discriminated Day 3 samples from Day 1, highlighting the key robustness of the developed lipid-biosynthesis signature. Highly significant (pFDR |
| format | Artículo científico |
| id | pubmed_39912956 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Marine biotechnology (New York, N.Y.) |
| record_format | pubmed |
| spellingShingle | Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20. Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong Stramenopiles Transcriptome Lipid Metabolism Australia Fatty Acids Gene Expression Profiling Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20. Lee Chang, Kim Jye Gorron Gomez, Eduardo Ebrahimie, Esmaeil Dehcheshmeh, Manijeh Mohammadi Frampton, Dion M F Zhou, Xue-Rong Stramenopiles Transcriptome Lipid Metabolism Australia Fatty Acids Gene Expression Profiling Aurantiochytrium not only excels in producing long-chain polyunsaturated fatty acids such as docosahexaenoic acid for humans, but it is also a source of essential fatty acids with minimal impacts on wild fisheries and is vital in the transfer of atmospheric carbon to oceanic carbon sinks and cycles. This study aims to unveil the systems biology of lipid production in the Australian Aurantiochytrium sp. TC20 by comparing the transcriptomic profiles under optimal growth conditions with increased fatty acid production from the early (Day 1) to late exponential growth phase (Day 3). Particular attention was paid to 227 manually annotated genes involved in lipid metabolism, such as FAS (fatty acid synthetase) and subunits of polyunsaturated fatty acids (PUFA) synthase. PCA analysis showed that differentially expressed genes, related to lipid metabolism, efficiently discriminated Day 3 samples from Day 1, highlighting the key robustness of the developed lipid-biosynthesis signature. Highly significant (pFDR |
| title | Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20. |
| topic | Stramenopiles Transcriptome Lipid Metabolism Australia Fatty Acids Gene Expression Profiling |
| url | https://pubmed.ncbi.nlm.nih.gov/39912956/ |