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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Heliyon
2025
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/39916849/ |
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Table of Contents:
- Integrated assessment of mucilage impact on human health using the One Health approach: Prevalence and antimicrobial resistance profiles of and in the Marmara Sea, Türkiye. Yibar, Artun Ay, Hilal Aydin, Fuat Abay, Secil Karakaya, Emre Kayman, Tuba Dalyan, Cem Koca, Fatih Dogan Aydogdu, Duygu Ajmi, Nihed Duman, Muhammed Saticioglu, Izzet Burcin This study employed a One Health approach to assess the potential impact of mucilage on human health by characterizing the prevalence and antimicrobial resistance (AMR) profiles of and strains isolated during the 2021 mucilage event in the Marmara Sea, Türkiye. Mucilage, a gelatinous organic substance exacerbated by climate change, disrupts marine ecosystems by depleting oxygen, threatening biodiversity, and serving as a reservoir for pathogenic microorganisms. Surface and benthic mucilage samples collected from the Marmara Sea were analysed for AMR profiles using genome analysis, the BD Phoenix™ 100 automated system, and E-test methods. The study identified 13 and one strain, harboring 244 and six AMR genes from 21 and eight drug classes, respectively, along with multiple virulence factors (VFs). The strains exhibited four distinct serotypes (O138:H28 [Mu-3], O18:H49 [Mu-4], O128:H12 [Mu-35] and O101:H10 [Mu-125]), reported for the first time from Türkiye and mucilage. Notably, anaerobic microorganisms like thrived in mucilage, underscoring their ecological significance. Seasonal and climatic factors influencing mucilage formation amplify its role in transmitting antimicrobial-resistant pathogens, posing significant risks to public and environmental health. The findings highlight the urgent need for continuous monitoring and mitigation strategies for mucilage-related hazards.