Imagen de Portada

Network Pharmacology Analysis and Biological Validation Systemically Identified the Active Ingredients and Molecular Targets of Kudzu Root on Osteoporosis.

Fuente: PubMed

Guardado en:

Detalles Bibliográficos
Autores principales:	Liu, Zhi-Wen, Zhang, Bo-Bo, Kwok, Kevin Wing-Hin, Dong, Xiao-Li, Wong, Ka-Hing
Formato:	Artículo científico
Lenguaje:	en
Publicado:	International journal of molecular sciences 2025
Materias:	Animals Zebrafish Network Pharmacology Pueraria Osteoporosis Molecular Docking Simulation Protein Interaction Maps Plant Roots Molecular Dynamics Simulation Signal Transduction Disease Models, Animal Plant Extracts Humans
Acceso en línea:	Acceder al recurso
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Identification of Compounds Inhibiting Thermolabile Hemolysin from in Shrimp.
por: Bari, Sayed Mashequl, et al.
Publicado: (2025)

The antifungal potential and mechanistic action of durian shell water extract against citrus pathogen Fusarium oxysporum.
por: Lin, Haiyan, et al.
Publicado: (2026)

Computational analysis of zoanthamine alkaloids from Zoanthus sp. as potential DKK1 and GSK-3β inhibitors for osteoporosis therapy via Wnt signaling.
por: Pham, Ngoc-Thac, et al.
Publicado: (2025)

Unveiling an indole derivative YM818 as a novel tyrosinase inhibitor with anti-melanogenic and anti-melanin transfer effects.
por: Yang, Chunyan, et al.
Publicado: (2025)

Decoding the multifunctional potential of ursolic acid: antioxidant, antiproliferative, molecular dynamics, and biodegradability evaluations of a mangrove-derived terpenoid.
por: Parthiban, Anaikutti, et al.
Publicado: (2025)

Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways.
por: Huang, Jing, et al.
Publicado: (2025)

The NeuroImmunoEndocrine Circuit of Umami Peptides: A Systems Biology Approach.
por: Hemmati, Shiva, et al.
Publicado: (2026)

Brevianamide F Exerts Antithrombotic Effects by Modulating the MAPK Signaling Pathway and Coagulation Cascade.
por: Zhang, Huiwen, et al.
Publicado: (2024)

Lichen Extracts Containing Volatile Compounds Induce Oxidative Stress and Modulate the Growth of and .
por: Essadki, Yasser, et al.
Publicado: (2026)

Epicoccin A Ameliorates PD-like Symptoms in Zebrafish: Enhancement of PINK1/Parkin-Dependent Mitophagy and Inhibition of Excessive Oxidative Stress.
por: Ye, Haicheng, et al.
Publicado: (2025)

An examination of the microbiome of Bacillus cereus (PS5) isolated from Puntius sarana (Olive barb) for α-amylase production, optimization, macromolecule extraction, and structural characterization with industrial and agricultural applications.
por: Dhayalan, Arul, et al.
Publicado: (2026)

Identification, Screening and Mechanism Analysis of Anti-Parkinson's Disease Peptides from Protein Hydrolysates.
por: Wang, Qingzhong, et al.
Publicado: (2026)

In Vitro and In Silico Studies on the Anti-H1N1 Activity of Bioactive Compounds from Marine-Derived .
por: Chen, Yung-Husan, et al.
Publicado: (2025)

Computational Analysis of Excavatolide B-Human STING Interactions Implicates a Cys148-Adjacent Corridor with Within-Cavity Sub-Pose Diversity.
por: Chang, Tien-Lin, et al.
Publicado: (2026)

Sirenin and bisabolane sesquiterpenoids from two marine isolates of Penicillium chermesinum with anti-osteoporotic activity by modulating NOD-like receptor signaling pathway.
por: Liu, Yi-Wei, et al.
Publicado: (2025)

Effects of Octacosanol Isolated from Leaves on Inhibiting the Activity of Pancreatic Lipase.
por: Dong, Xiaoying, et al.
Publicado: (2025)

Attenuating Vibrio harveyi Virulence Through Quorum Sensing Interference Using Piperine: An In Vitro and In Silico Approach.
por: Arcan, Stephen Kyle C, et al.
Publicado: (2025)

Unveiling the potential of Hamigeran-B from marine sponges as a probable inhibitor of Nipah virus RDRP through molecular modelling and dynamics simulation studies.
por: Skariyachan, S, et al.
Publicado: (2024)

Computational Analysis of Azole Derivatives Targeting the PI3K/AKT/mTOR Pathway With In Vitro Cytotoxicity and Autophagy Evaluation.
por: Regurajan, Rathika, et al.
Publicado: (2026)

Exploring Marine natural products as potential Quorum sensing inhibitors by targeting the PqsR in Pseudomonas aeruginosa: Virtual screening assisted structural dynamics study.
por: Jayaraman, Manikandan, et al.
Publicado: (2025)

Robinin Isolated From Solanum Asperum Exhibits Pharmacological Actions in the Central Nervous System of Adult Zebrafish (Danio rerio).
por: Lemos, Cecília Guimarães, et al.
Publicado: (2025)

In silico evaluation of bioactive compounds from the sea urchin Temnopleurus toreumaticus: Potential multifunctional agents against mosquito vectors and tropical pathogens.
por: Ramachandran, Karnan, et al.
Publicado: (2026)

Binding Stability and Catalytic Mechanism of a Novel Chitin Deacetylase from and Preparation of Chitosan.
por: Liang, Bicheng, et al.
Publicado: (2025)

Identification of Antioxidant and Anti-Inflammatory Activity of Sea Cucumber () Active Peptides by a Combined Approach of Omics Data and Bioinformatics Analysis.
por: La Paglia, Laura, et al.
Publicado: (2026)

Marine algae-derived Ag/AlO and Ag/CoO/AlO nanohybrids: A green approach to phytochemical profiling, molecular docking, and bioactivity assessment.
por: Alshammari, Mohammed S, et al.
Publicado: (2026)

Phytochemicals From Hansenia weberbaueriana for Psoriasis and Inflammatory Bowel Disease Comorbidity: Based on Network Pharmacology and In Vitro Analysis.
por: Tian, Yuhong, et al.
Publicado: (2025)

Revealing the molecular mechanisms underlying Xuebijing against sepsis and septic acute kidney injury via bioinformatics and experimental approaches.
por: Li, Xing, et al.
Publicado: (2025)

A fish-specific antimicrobial peptide Piscidin2 inactivates MSRV and confers protection in largemouth bass.
por: Fei, Chenjie, et al.
Publicado: (2025)

The Antioxidant Effects of Trypsin-Hydrolysate Derived from Abalone Viscera and Fishery By-Products, and the Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity of Its Purified Bioactive Peptides.
por: Heo, Jun-Ho, et al.
Publicado: (2024)

Stellarin I: A Bioactive Cyclic Nonapeptide with Potent Anti-renal Fibrosis Activity from the Root of Stellaria yunnanensis Franch.
por: Deng, Ruixuan, et al.
Publicado: (2025)

Evaluating the estrogen degradation potential of laccase and peroxidase from Bacillus ligniniphilus L1 through integrated computational and experimental approaches.
por: Nawaz, Muhammad Zohaib, et al.
Publicado: (2024)

From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations.
por: Zhang, Haorui, et al.
Publicado: (2026)

Antithrombotic Effect of L. Extract and Its Fractions via Regulating TLRs and the Downstream MAPKs and PI3K/AKT Signaling Pathways in Zebrafish.
por: Wang, Xiyue, et al.
Publicado: (2025)

Decoding the catalytic potential of a Cycloclasticus zancles ring-hydroxylating dioxygenase through computational analysis for enhanced PAH biodegradation.
por: Naveed, Muhammad, et al.
Publicado: (2026)

Identification and anticoagulant mechanisms of novel factor XIa inhibitory peptides by virtual screening of a in silico generated deep-sea peptide database.
por: Ouyang, Yuhong, et al.
Publicado: (2024)

Isolation and Purification of Novel Antioxidant Peptides from Mussel () Prepared by Marine Z-1 Protease.
por: Lu, Jing, et al.
Publicado: (2025)

Structure-Activity Relationships, Molecular Mechanisms, and Ecotoxicological Evaluation Underlying Nucleoside-Mediated Antifouling Activity.
por: Pereira, Sandra, et al.
Publicado: (2026)

Structural and functional insights into glycosyltransferase from Nocardia asteroides NCTC11293 and structure-guided discovery of marine and phytochemical leads through pharmacokinetic screening and molecular dynamics studies.
por: Muthuvairam Subbulakshmi, Maharaja, et al.
Publicado: (2026)

Elucidation of anti-human melanoma and anti-aging mechanisms of compounds from green seaweed Caulerpa racemosa.
por: Wicaksono, Danar, et al.
Publicado: (2024)

Molecular docking and in vitro anticancer evaluation of potential compounds derived from Indonesian sponge Agelas nakamurai.
por: Budiyanto, Fitri, et al.
Publicado: (2025)