Unveiling an indole derivative YM818 as a novel tyrosinase inhibitor with anti-melanogenic and anti-melanin transfer effects.
Fuente:
PubMed
Salvato in:
| Autori principali: | Yang, Chunyan, Lai, Huixian, Yang, Xiaoyu, Huang, Yuehong, Shi, Yan, Ke, Lina, Chen, Lizhu, Chen, Mingliang, Chen, Hongbin, Wang, Qin |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
International journal of biological macromolecules
2025
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
Documenti analoghi
Bioactivity and Chemical Profiling of the Sea-Ice Microalga (Chlorophyceae).
di: Trentin, Riccardo, et al.
Pubblicazione: (2025)
di: Trentin, Riccardo, et al.
Pubblicazione: (2025)
Molecular mechanisms of melanin-mediated shell pigmentation in Mytilus coruscus: Functional characterization of Tyr family genes and regulatory pathways.
di: Zheng, Xiaoxu, et al.
Pubblicazione: (2026)
di: Zheng, Xiaoxu, et al.
Pubblicazione: (2026)
Exploration of UHPLC-ESI-QTOF-MS Profiles and the Neuroprotective, Antidiabetic, Antioxidant and Cytotoxic Effects of Extracts from Achillea maritima (L.) Ehrend. & Y.P.Guo (Asteraceae) Collected in Türkiye.
di: Ahmed, Shakeel, et al.
Pubblicazione: (2025)
di: Ahmed, Shakeel, et al.
Pubblicazione: (2025)
Structure-Activity Relationships, Molecular Mechanisms, and Ecotoxicological Evaluation Underlying Nucleoside-Mediated Antifouling Activity.
di: Pereira, Sandra, et al.
Pubblicazione: (2026)
di: Pereira, Sandra, et al.
Pubblicazione: (2026)
Computational analysis of the deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) in TYR gene impacting human tyrosinase protein and the protein stability.
di: Fan, Wei, et al.
Pubblicazione: (2024)
di: Fan, Wei, et al.
Pubblicazione: (2024)
Engineered Marine Biofilms for Ocean Environment Monitoring.
di: Nevot, Guillermo, et al.
Pubblicazione: (2025)
di: Nevot, Guillermo, et al.
Pubblicazione: (2025)
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
di: Chen, Xiaohui, et al.
Pubblicazione: (2025)
di: Chen, Xiaohui, et al.
Pubblicazione: (2025)
Diverse and Bioactive Lactones from the Sri Lankan Mangrove-Derived Fungus sp. SCSIO41445.
di: Wijerathna, Parakkrama, et al.
Pubblicazione: (2026)
di: Wijerathna, Parakkrama, et al.
Pubblicazione: (2026)
Computational screening of natural plant and marine compounds as potential inhibitors of Mycobacterium tuberculosis dihydrodipicolinate synthase.
di: Meena, Swati, et al.
Pubblicazione: (2026)
di: Meena, Swati, et al.
Pubblicazione: (2026)
The Antioxidant Effects of Trypsin-Hydrolysate Derived from Abalone Viscera and Fishery By-Products, and the Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity of Its Purified Bioactive Peptides.
di: Heo, Jun-Ho, et al.
Pubblicazione: (2024)
di: Heo, Jun-Ho, et al.
Pubblicazione: (2024)
Selective Synthesis of Cyclopeptides with a 2-Oxindole or 3a-Hydroxy-hexahydropyrrolo-[2,3-]indole Structure by Cytochrome P450 Enzymes.
di: Li, Chao, et al.
Pubblicazione: (2025)
di: Li, Chao, et al.
Pubblicazione: (2025)
Inhibition of Na,K -ATPase enzyme by tetrodotoxin extract in the breast tumor xenograft Balb/c nu mouse model.
di: Ahrari, Ameneh, et al.
Pubblicazione: (2025)
di: Ahrari, Ameneh, et al.
Pubblicazione: (2025)
From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations.
di: Zhang, Haorui, et al.
Pubblicazione: (2026)
di: Zhang, Haorui, et al.
Pubblicazione: (2026)
Elucidating the role of -derived indole metabolites in gut inflammation and immune modulation.
di: Park, Jong-Duk, et al.
Pubblicazione: (2025)
di: Park, Jong-Duk, et al.
Pubblicazione: (2025)
Effects of Octacosanol Isolated from Leaves on Inhibiting the Activity of Pancreatic Lipase.
di: Dong, Xiaoying, et al.
Pubblicazione: (2025)
di: Dong, Xiaoying, et al.
Pubblicazione: (2025)
Optimized ebselen derivatives as novel potent Escherichia coli β-glucuronidase covalent allosteric inhibitors.
di: Ying, Ti-Ti, et al.
Pubblicazione: (2025)
di: Ying, Ti-Ti, et al.
Pubblicazione: (2025)
Discovery and molecular mechanism of a novel antihypertensive peptide from Chlamydomonas reinhardtii based on molecular docking, molecular dynamics simulation, in vitro, and in vivo analysis.
di: Suo, Qishan, et al.
Pubblicazione: (2026)
di: Suo, Qishan, et al.
Pubblicazione: (2026)
Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
di: Chandrasekaran, Vishnupriya, et al.
Pubblicazione: (2025)
di: Chandrasekaran, Vishnupriya, et al.
Pubblicazione: (2025)
Conkazal-M1 from the MKAVA family of conotoxins: A dual-function protease inhibitor and neuroactive peptide.
di: Hackney, Celeste M, et al.
Pubblicazione: (2026)
di: Hackney, Celeste M, et al.
Pubblicazione: (2026)
Inhibition of MMP-2/MMP-9 and biofilm formation by 4,5,7-trihydroxyflavanone (THF): a promising therapeutic approach against Enterococcus gallinarum endocarditis.
di: Hyderi, Zeeshan, et al.
Pubblicazione: (2025)
di: Hyderi, Zeeshan, et al.
Pubblicazione: (2025)
Production and inhibition of human Heparan 6-O-Endosulfatase SULF1.
di: Aljuhani, Reem, et al.
Pubblicazione: (2025)
di: Aljuhani, Reem, et al.
Pubblicazione: (2025)
Cuttlefish Ink-Derived Melanin Nanoparticles Enabling NIR-Responsive Electrospun Nanofibrous Mats for On-Demand Selective Antibacterial Disinfection of Orthodontic Braces.
di: Bartolewska, Magdalena, et al.
Pubblicazione: (2026)
di: Bartolewska, Magdalena, et al.
Pubblicazione: (2026)
Identification and functional analysis of a novel potent anti-angiogenesis peptide SAIF-B2 derived from shark cartilage.
di: Xie, Junye, et al.
Pubblicazione: (2025)
di: Xie, Junye, et al.
Pubblicazione: (2025)
Heparan-6-O-endosulfatase 2, a cancer-related proteoglycan enzyme, is effectively inhibited by a specific sea cucumber fucosylated glycosaminoglycan.
di: Farrag, Marwa, et al.
Pubblicazione: (2025)
di: Farrag, Marwa, et al.
Pubblicazione: (2025)
Systematic review on the full-process preparation, characterization and application of drug-loaded melanin nanoparticles.
di: Cheng, Xinrong, et al.
Pubblicazione: (2025)
di: Cheng, Xinrong, et al.
Pubblicazione: (2025)
Quantitative Structure-Activity Relationship and Molecular Modeling Studies on a Series of Hydroxypyrrolo[2,1-c][1,4]Benzodiazepine-5,11-dione Acting as Angiotensin Converting Enzyme I Inhibitors
di: Sanober, Ayesha, et al.
Pubblicazione: (2021)
di: Sanober, Ayesha, et al.
Pubblicazione: (2021)
Quantifying serotonin in four aquatic invertebrates using enzyme-linked immunosorbent assays (ELISA): Implications for assessing selective serotonin reuptake inhibitor (SSRI) effects.
di: Lautrette-Quinveros, Harmony, et al.
Pubblicazione: (2026)
di: Lautrette-Quinveros, Harmony, et al.
Pubblicazione: (2026)
Sirenin and bisabolane sesquiterpenoids from two marine isolates of Penicillium chermesinum with anti-osteoporotic activity by modulating NOD-like receptor signaling pathway.
di: Liu, Yi-Wei, et al.
Pubblicazione: (2025)
di: Liu, Yi-Wei, et al.
Pubblicazione: (2025)
Computer-aided screening of marine fungal metabolites as potential inhibitors of new Delhi metallo-beta-lactamase-1.
di: Shabbir, Farhat, et al.
Pubblicazione: (2025)
di: Shabbir, Farhat, et al.
Pubblicazione: (2025)
Anticoagulant and angiotensin-converting enzyme inhibitory activities of a fucoidan from and its low molecular weight fragments prepared by acid degradation.
di: Liu, Xue, et al.
Pubblicazione: (2026)
di: Liu, Xue, et al.
Pubblicazione: (2026)
Okadaic acid induces oxidative stress and immunotoxicity in zebrafish: involvement of the p53 pathway and behavioral alterations.
di: Chen, Duo, et al.
Pubblicazione: (2026)
di: Chen, Duo, et al.
Pubblicazione: (2026)
A TRPV1 agonist from the transcriptome profiling of Dipsastraea rotumana inhibits neuroinflammation in vivo through the NF-κB and MAPK pathways.
di: Chen, Hanbin, et al.
Pubblicazione: (2025)
di: Chen, Hanbin, et al.
Pubblicazione: (2025)
Novel peptide inhibitor of matrix Metalloproteinases-1 from pufferfish skin collagen hydrolysates and its potential Photoprotective activity via the MAPK/AP-1 signaling pathway.
di: Chen, Bei, et al.
Pubblicazione: (2025)
di: Chen, Bei, et al.
Pubblicazione: (2025)
Marine-derived Streptomyces sp. isolated from the Persian Gulf as a novel source of melanin.
di: Malekpour, Seyed Muhammad Hamid, et al.
Pubblicazione: (2026)
di: Malekpour, Seyed Muhammad Hamid, et al.
Pubblicazione: (2026)
Eremophilane- and Acorane-Type Sesquiterpenes from the Deep-Sea Cold-Seep-Derived Fungus CS-280 Cultured in the Presence of Autoclaved QDIO-4.
di: Chen, Xiao-Dan, et al.
Pubblicazione: (2024)
di: Chen, Xiao-Dan, et al.
Pubblicazione: (2024)
Prkra dimer senses double-stranded RNAs to dictate global translation efficiency.
di: Lu, Tong, et al.
Pubblicazione: (2025)
di: Lu, Tong, et al.
Pubblicazione: (2025)
Innovative CuO-melanin hybrid nanoparticles and polytetrafluoroethylene for enhanced antifouling coatings.
di: Ghattavi, Saba, et al.
Pubblicazione: (2025)
di: Ghattavi, Saba, et al.
Pubblicazione: (2025)
Targeting marine jellyfish toxins: development of metalloproteinase inhibitors through a specific method for protease substrate identification.
di: Yu, Chunlin, et al.
Pubblicazione: (2026)
di: Yu, Chunlin, et al.
Pubblicazione: (2026)
The New Delhi Metallo-β-lactamase-1 Covalent Inhibitors Derived from Cephalexin Effectively Reverse Meropenem Resistance.
di: Liu, Wandong, et al.
Pubblicazione: (2026)
di: Liu, Wandong, et al.
Pubblicazione: (2026)
Design, Synthesis, and Evaluation of a Potent and Selective ROCK2 Inhibitor for Atopic Dermatitis Treatment.
di: Mao, Churu, et al.
Pubblicazione: (2026)
di: Mao, Churu, et al.
Pubblicazione: (2026)
Documenti analoghi
-
Bioactivity and Chemical Profiling of the Sea-Ice Microalga (Chlorophyceae).
di: Trentin, Riccardo, et al.
Pubblicazione: (2025) -
Molecular mechanisms of melanin-mediated shell pigmentation in Mytilus coruscus: Functional characterization of Tyr family genes and regulatory pathways.
di: Zheng, Xiaoxu, et al.
Pubblicazione: (2026) -
Exploration of UHPLC-ESI-QTOF-MS Profiles and the Neuroprotective, Antidiabetic, Antioxidant and Cytotoxic Effects of Extracts from Achillea maritima (L.) Ehrend. & Y.P.Guo (Asteraceae) Collected in Türkiye.
di: Ahmed, Shakeel, et al.
Pubblicazione: (2025) -
Structure-Activity Relationships, Molecular Mechanisms, and Ecotoxicological Evaluation Underlying Nucleoside-Mediated Antifouling Activity.
di: Pereira, Sandra, et al.
Pubblicazione: (2026) -
Computational analysis of the deleterious non-synonymous single nucleotide polymorphisms (nsSNPs) in TYR gene impacting human tyrosinase protein and the protein stability.
di: Fan, Wei, et al.
Pubblicazione: (2024)