Anti-inflammatory agents design via the fragment hybrid strategy in the discovery of compound c1 for treating ALI and UC.
Fuente:
PubMed
Salvato in:
| Autori principali: | Guo, Mi, Zou, Yu, Dong, Ke, Huang, Nan, Chen, Zhichao, Sun, Chenhui, Chen, Pan, Chen, Qi, Zhu, Luxiao, Lv, Yuehua, Zhang, Kaixin, Jiang, Miao, Gao, Yitian, Cho, Young-Chang, Tang, Qidong, Liang, Guang, Wu, Di |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
European journal of medicinal chemistry
2025
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
Documenti analoghi
Multi-omics integrative analysis elucidates the anti-inflammatory effects and underlying mechanisms of Arthrospira platensis-derived peptides in ulcerative colitis.
di: Yang, Fanghao, et al.
Pubblicazione: (2026)
di: Yang, Fanghao, et al.
Pubblicazione: (2026)
Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
di: Chandrasekaran, Vishnupriya, et al.
Pubblicazione: (2025)
di: Chandrasekaran, Vishnupriya, et al.
Pubblicazione: (2025)
In Vitro Antioxidant and Anti-Inflammatory Activities of Seaweeds From the Bay of Bengal Coastal Region in Lipopolysaccharide-Induced RAW264.7 Cells.
di: Perumal, Parthasarathi, et al.
Pubblicazione: (2025)
di: Perumal, Parthasarathi, et al.
Pubblicazione: (2025)
Lobopaucinoids A-Q, bioactive terpenoids from the soft coral Lobophytum pauciflorum collected in the South China Sea.
di: Han, Xiao, et al.
Pubblicazione: (2025)
di: Han, Xiao, et al.
Pubblicazione: (2025)
9H-carbazole derivatives from a Streptomyces species under potassium iodide stress and their anti-inflammatory properties.
di: Yan, Pengcheng, et al.
Pubblicazione: (2025)
di: Yan, Pengcheng, et al.
Pubblicazione: (2025)
Fucoidan Extracted from Ameliorates Colitis-Associated Neuroinflammation and Anxiety-like Behavior in Adult C57BL/6 Mice.
di: Song, Xiaoyu, et al.
Pubblicazione: (2026)
di: Song, Xiaoyu, et al.
Pubblicazione: (2026)
Anti-inflammatory and analgesic effects of marine-derived antimicrobial peptide tilapia piscidin 3(TP3) in alleviating chronic constriction injury-induced neuropathic pain in rats.
di: Tsai, Jui-Kang, et al.
Pubblicazione: (2025)
di: Tsai, Jui-Kang, et al.
Pubblicazione: (2025)
Identification of monomethylsulochrin as a novel agent to ameliorate DSS-induced ulcerative colitis through dual modulation of the IL-17/TNF pathway and gut microbiota.
di: Xing, Shangping, et al.
Pubblicazione: (2026)
di: Xing, Shangping, et al.
Pubblicazione: (2026)
Xiapyrroles A-F: -Alkylpyrrole Alkaloids from the Marine-Derived Actinomycete 1310KO-148.
di: Lee, Min Ah, et al.
Pubblicazione: (2025)
di: Lee, Min Ah, et al.
Pubblicazione: (2025)
Fucoxanthin ameliorates ulcerative colitis by maintaining the epithelial barrier via blocking JAK2/STAT3 signaling pathway.
di: Ma, Jingjing, et al.
Pubblicazione: (2025)
di: Ma, Jingjing, et al.
Pubblicazione: (2025)
Recent Advances in Steroid Discovery: Structural Diversity and Bioactivity of Marine and Terrestrial Steroids.
di: Hajdaś, Grzegorz, et al.
Pubblicazione: (2025)
di: Hajdaś, Grzegorz, et al.
Pubblicazione: (2025)
Undescribed alkaloids, peptides and polyketides from marine sediment-derived fungus Aspergillus terreus PPS1.
di: Zheng, Yao-Yao, et al.
Pubblicazione: (2025)
di: Zheng, Yao-Yao, et al.
Pubblicazione: (2025)
An abundant ginger compound furanodienone alleviates gut inflammation via the xenobiotic nuclear receptor PXR in mice.
di: Wang, Xiaojuan, et al.
Pubblicazione: (2025)
di: Wang, Xiaojuan, et al.
Pubblicazione: (2025)
Structure-function relationship of the brown seaweed Undaria pinnatifida laminaran: Protein kinase C-mediated mucus secretion and gut barrier restoration.
di: Cheong, Kit-Leong, et al.
Pubblicazione: (2025)
di: Cheong, Kit-Leong, et al.
Pubblicazione: (2025)
An immunomodulatory ochratoxin analogue from marine Aspergillus sp. potentiates macrophage defense against Edwardsiella tarda via AIFM1-mediated necroptosis inhibition.
di: Liu, Yan-Jun, et al.
Pubblicazione: (2026)
di: Liu, Yan-Jun, et al.
Pubblicazione: (2026)
Anti-Inflammatory Activity of Labdane and Norlabdane Diterpenoids from Leonurus sibiricus Related to Modulation of MAPKs Signaling Pathway.
di: Trang, Nguyen Minh, et al.
Pubblicazione: (2025)
di: Trang, Nguyen Minh, et al.
Pubblicazione: (2025)
Total synthesis and target identification of marine cyclopiane diterpenes.
di: Li, Tian, et al.
Pubblicazione: (2024)
di: Li, Tian, et al.
Pubblicazione: (2024)
Cacomalides A-G, Manoalide-Related Sesterterpenes With Anti-Inflammatory Activities From the Marine Sponge Cacosponges sp.
di: Zhang, Wenjie, et al.
Pubblicazione: (2025)
di: Zhang, Wenjie, et al.
Pubblicazione: (2025)
Degradation of NLRP3 by selective ROCK2 inhibitor alleviates acute lung injury.
di: Zhan, Shuai, et al.
Pubblicazione: (2025)
di: Zhan, Shuai, et al.
Pubblicazione: (2025)
Mucoadhesive lignin-liposome nanocarriers of coptisine: A multifunctional strategy against antibiotic-resistant Helicobacter pylori biofilms.
di: Sharaf, Mohamed, et al.
Pubblicazione: (2026)
di: Sharaf, Mohamed, et al.
Pubblicazione: (2026)
Disulfide-bonded YC18: A membrane-targeting peptide with superior efficacy against Staphylococcus aureus infections.
di: Gao, Jinai, et al.
Pubblicazione: (2026)
di: Gao, Jinai, et al.
Pubblicazione: (2026)
Kallikrein inhibitor derived from immunoglobulin heavy chain junction region possesses anti-thromboinflammation potential.
di: Yang, Juan, et al.
Pubblicazione: (2024)
di: Yang, Juan, et al.
Pubblicazione: (2024)
Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.
di: Liu, Wandong, et al.
Pubblicazione: (2025)
di: Liu, Wandong, et al.
Pubblicazione: (2025)
Zika virus: clinical manifestations and treatment at a primary care institution in Colombia
di: Juan Daniel Castrillón-Spitia
Pubblicazione: (2020)
di: Juan Daniel Castrillón-Spitia
Pubblicazione: (2020)
Genome analysis-led discovery of antimicrobial and herbicidal cytochalasans from the cold-seep-sourced endozoic Curvularia verruculosa CS-129.
di: Hu, Xue-Yi, et al.
Pubblicazione: (2026)
di: Hu, Xue-Yi, et al.
Pubblicazione: (2026)
Macroalgae-Inspired Brominated Chalcones as Cosmetic Ingredients with the Potential to Target Skin Inflammaging.
di: Jesus, Ana, et al.
Pubblicazione: (2025)
di: Jesus, Ana, et al.
Pubblicazione: (2025)
Bioactive Peptides: Production Strategies, Biological Activities, and Emerging Therapeutic Applications.
di: Saini, Jasvinder, et al.
Pubblicazione: (2026)
di: Saini, Jasvinder, et al.
Pubblicazione: (2026)
Cinerols L-R, Anti-inflammatory Meroterpenoids from the Marine Sponge .
di: Shang, Ru-Yi, et al.
Pubblicazione: (2025)
di: Shang, Ru-Yi, et al.
Pubblicazione: (2025)
LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.
di: Asmamaw, Demeke, et al.
Pubblicazione: (2026)
di: Asmamaw, Demeke, et al.
Pubblicazione: (2026)
Marine-Derived Alternariol Suppresses Inflammation by Regulating T Cell Activation and Migration.
di: Liu, Chenfeng, et al.
Pubblicazione: (2025)
di: Liu, Chenfeng, et al.
Pubblicazione: (2025)
Analysis of Cembrane-Type Diterpenoids from Cultured Soft Coral for Inhibition of TGF-β-Induced IL-6 Secretion in Inflammation-Associated Cancer.
di: Wang, Yi-Chen, et al.
Pubblicazione: (2025)
di: Wang, Yi-Chen, et al.
Pubblicazione: (2025)
Therapeutic potential of tryptophan metabolite indoleacrylic acid in inflammatory bowel disease: From cellular mechanisms to zebrafish stress-like behavior.
di: Amarasiri, R P G S K, et al.
Pubblicazione: (2025)
di: Amarasiri, R P G S K, et al.
Pubblicazione: (2025)
A Cinderella story in antimicrobials: CDPDP's perfect fit for multiple-pathway bacterial inhibition.
di: Ul Hassan, Syed Shams, et al.
Pubblicazione: (2025)
di: Ul Hassan, Syed Shams, et al.
Pubblicazione: (2025)
Aspergillusidone G Exerts Anti-Neuroinflammatory Effects via Inhibiting MMP9 Through Integrated Bioinformatics and Experimental Analysis: Implications for Parkinson's Disease Intervention.
di: Ban, Fangfang, et al.
Pubblicazione: (2025)
di: Ban, Fangfang, et al.
Pubblicazione: (2025)
Discovery of 4-(2-(methylamino)thiazol-5-yl)pyrimidin-2-amine derivatives as novel cyclin-dependent kinase 12 (CDK12) inhibitors for the treatment of esophageal squamous cell carcinoma.
di: Cao, Yin, et al.
Pubblicazione: (2025)
di: Cao, Yin, et al.
Pubblicazione: (2025)
Programmable Biohybrid Probiotics with Long-Term Storage Stability for Enhanced Intestinal Microbiota Regulation and Ulcerative Colitis Treatment.
di: Jiang, Jiani, et al.
Pubblicazione: (2026)
di: Jiang, Jiani, et al.
Pubblicazione: (2026)
Sirenin and bisabolane sesquiterpenoids from two marine isolates of Penicillium chermesinum with anti-osteoporotic activity by modulating NOD-like receptor signaling pathway.
di: Liu, Yi-Wei, et al.
Pubblicazione: (2025)
di: Liu, Yi-Wei, et al.
Pubblicazione: (2025)
Metabolic Shunting in Marine-Derived sp. SYSU-MS4722 Yields Diverse γ-Butyrolactone Derivatives with Anti-inflammatory Activity.
di: Yuan, Siwen, et al.
Pubblicazione: (2025)
di: Yuan, Siwen, et al.
Pubblicazione: (2025)
Discovery of novel thiosemicarbazone dimers as effective inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) for use in cancer therapy.
di: Wang, Lijun, et al.
Pubblicazione: (2026)
di: Wang, Lijun, et al.
Pubblicazione: (2026)
Discovery of an orally bioavailable pyridone-based BRD4 inhibitor with potent antitumor efficacy in colorectal cancer.
di: Fang, Zhangyun, et al.
Pubblicazione: (2026)
di: Fang, Zhangyun, et al.
Pubblicazione: (2026)
Documenti analoghi
-
Multi-omics integrative analysis elucidates the anti-inflammatory effects and underlying mechanisms of Arthrospira platensis-derived peptides in ulcerative colitis.
di: Yang, Fanghao, et al.
Pubblicazione: (2026) -
Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
di: Chandrasekaran, Vishnupriya, et al.
Pubblicazione: (2025) -
In Vitro Antioxidant and Anti-Inflammatory Activities of Seaweeds From the Bay of Bengal Coastal Region in Lipopolysaccharide-Induced RAW264.7 Cells.
di: Perumal, Parthasarathi, et al.
Pubblicazione: (2025) -
Lobopaucinoids A-Q, bioactive terpenoids from the soft coral Lobophytum pauciflorum collected in the South China Sea.
di: Han, Xiao, et al.
Pubblicazione: (2025) -
9H-carbazole derivatives from a Streptomyces species under potassium iodide stress and their anti-inflammatory properties.
di: Yan, Pengcheng, et al.
Pubblicazione: (2025)