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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Marine pollution bulletin
2025
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| Sujets: | |
| Accès en ligne: | https://pubmed.ncbi.nlm.nih.gov/40049112/ |
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| author | Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait |
| author_facet | Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait |
| collection | PubMed - marine biology |
| contents | Effects of selected heavy metals on neuronal differentiation of Asian seabass spinal cord cell line. Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait Animals Metals, Heavy Cell Differentiation Neurons Spinal Cord Bass Cell Line Water Pollutants, Chemical Asian seabass spinal cord cell line (SBSC) can be differentiated into neuron-like phenotypes through induction with neurotrophin-3 (NT-3), all-trans-retinoic acid (ATRA) and Insulin-like growth factor-I human (IGFI). Following differentiation, this cell line could be used as an in vitro models for investigating various aspects of neuronal cell biology. The study of metal cytotoxicity involved the use of Asian seabass, an important marine fish. The present study was to determine the cytotoxicity of eleven heavy metals (Fe, Co, Cd, Cu, Na, Hg, Zn, In, Al, Lu and Cr) in the SBSC cell line based on MTT, neutral red (NR) uptake assays and ROS production. This study determined the effective concentrations (EC and EC) of eleven metals in SBSC cells. The result of the present study demonstrates that the EC concentration of selected metals affects the neuronal differentiation in the SBSC cells. |
| format | Artículo científico |
| id | pubmed_40049112 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Marine pollution bulletin |
| record_format | pubmed |
| spellingShingle | Effects of selected heavy metals on neuronal differentiation of Asian seabass spinal cord cell line. Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait Animals Metals, Heavy Cell Differentiation Neurons Spinal Cord Bass Cell Line Water Pollutants, Chemical Effects of selected heavy metals on neuronal differentiation of Asian seabass spinal cord cell line. Mithra, Sivaraj Madiha Fathima, Basheer Abdul Majeed, Seepoo Taju, Gani Mohammed Safiullah, Sakvai Mujthaba Aatif, Arni Vimal, Sugumar Zehra, Amtuz Martina, Sahayarajan Ghousia Nisha, Ahmed Hussain Sahul Hameed, Azeez Sait Animals Metals, Heavy Cell Differentiation Neurons Spinal Cord Bass Cell Line Water Pollutants, Chemical Asian seabass spinal cord cell line (SBSC) can be differentiated into neuron-like phenotypes through induction with neurotrophin-3 (NT-3), all-trans-retinoic acid (ATRA) and Insulin-like growth factor-I human (IGFI). Following differentiation, this cell line could be used as an in vitro models for investigating various aspects of neuronal cell biology. The study of metal cytotoxicity involved the use of Asian seabass, an important marine fish. The present study was to determine the cytotoxicity of eleven heavy metals (Fe, Co, Cd, Cu, Na, Hg, Zn, In, Al, Lu and Cr) in the SBSC cell line based on MTT, neutral red (NR) uptake assays and ROS production. This study determined the effective concentrations (EC and EC) of eleven metals in SBSC cells. The result of the present study demonstrates that the EC concentration of selected metals affects the neuronal differentiation in the SBSC cells. |
| title | Effects of selected heavy metals on neuronal differentiation of Asian seabass spinal cord cell line. |
| topic | Animals Metals, Heavy Cell Differentiation Neurons Spinal Cord Bass Cell Line Water Pollutants, Chemical |
| url | https://pubmed.ncbi.nlm.nih.gov/40049112/ |