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The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project.

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Auteurs principaux:	Fang, Lingzhao, Teng, Jinyan, Lin, Qing, Bai, Zhonghao, Liu, Shuli, Guan, Dailu, Li, Bingjie, Gao, Yahui, Hou, Yali, Gong, Mian, Pan, Zhangyuan, Yu, Ying, Clark, Emily L, Smith, Jacqueline, Rawlik, Konrad, Xiang, Ruidong, Chamberlain, Amanda J, Goddard, Michael E, Littlejohn, Mathew, Larson, Greger, MacHugh, David E, O'Grady, John F, Sørensen, Peter, Sahana, Goutam, Lund, Mogens Sandø, Jiang, Zhihua, Pan, Xiangchun, Gong, Wentao, Zhang, Haihan, He, Xi, Zhang, Yuebo, Gao, Ning, He, Jun, Yi, Guoqiang, Liu, Yuwen, Tang, Zhonglin, Zhao, Pengju, Zhou, Yang, Fu, Liangliang, Wang, Xiao, Hao, Dan, Liu, Lei, Chen, Siqian, Young, Robert S, Shen, Xia, Xia, Charley, Cheng, Hao, Ma, Li, Cole, John B, Baldwin, Ransom L, Li, Cong-Jun, Van Tassell, Curtis P, Rosen, Benjamin D, Bhowmik, Nayan, Lunney, Joan, Liu, Wansheng, Guan, Leluo, Zhao, Xin, Ibeagha-Awemu, Eveline M, Luo, Yonglun, Lin, Lin, Canela-Xandri, Oriol, Derks, Martijn F L, Crooijmans, Richard P M A, Gòdia, Marta, Madsen, Ole, Groenen, Martien A M, Koltes, James E, Tuggle, Christopher K, McCarthy, Fiona M, Rocha, Dominique, Giuffra, Elisabetta, Amills, Marcel, Clop, Alex, Ballester, Maria, Tosser-Klopp, Gwenola, Li, Jing, Fang, Chao, Fang, Ming, Wang, Qishan, Hou, Zhuocheng, Wang, Qin, Zhao, Fuping, Jiang, Lin, Zhao, Guiping, Zhou, Zhengkui, Zhou, Rong, Liu, Hehe, Deng, Juan, Jin, Long, Li, Mingzhou, Mo, Delin, Liu, Xiaohong, Chen, Yaosheng, Yuan, Xiaolong, Li, Jiaqi, Zhao, Shuhong, Zhang, Yi, Ding, Xiangdong, Sun, Dongxiao, Sun, Hui-Zeng, Li, Cong, Wang, Yu, Jiang, Yu, Wu, Dongdong, Wang, Wenwen, Fan, Xinzhong, Zhang, Qin, Li, Kui, Zhang, Hao, Yang, Ning, Hu, Xiaoxiang, Huang, Wen, Song, Jiuzhou, Wu, Yang, Yang, Jian, Wu, Weiwei, Kasper, Claudia, Liu, Xinfeng, Yu, Xiaofei, Cui, Leilei, Zhou, Xiang, Kim, Seyoung, Li, Wei, Im, Hae Kyung, Buckler, Edward S, Ren, Bing, Schatz, Michael C, Li, Jingyi Jessica, Palmer, Abraham A, Frantz, Laurent, Zhou, Huaijun, Zhang, Zhe, Liu, George E
Format:	Artículo científico
Langue:	en
Publié:	Nature genetics 2025
Sujets:	Animals Animals, Domestic Genotype Humans Transcriptome Genomics Phenotype
Accès en ligne:	Acceder al recurso
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_version_	1868266228867399681
author	Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E
author_facet	Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E
collection	PubMed - marine biology
contents	The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E Animals Animals, Domestic Genotype Humans Transcriptome Genomics Phenotype Genetic mutation and drift, coupled with natural and human-mediated selection and migration, have produced a wide variety of genotypes and phenotypes in farmed animals. We here introduce the Farm Animal Genotype-Tissue Expression (FarmGTEx) Project, which aims to elucidate the genetic determinants of gene expression across 16 terrestrial and aquatic domestic species under diverse biological and environmental contexts. For each species, we aim to collect multiomics data, particularly genomics and transcriptomics, from 50 tissues of 1,000 healthy adults and 200 additional animals representing a specific context. This Perspective provides an overview of the priorities of FarmGTEx and advocates for coordinated strategies of data analysis and resource-sharing initiatives. FarmGTEx aims to serve as a platform for investigating context-specific regulatory effects, which will deepen our understanding of molecular mechanisms underlying complex phenotypes. The knowledge and insights provided by FarmGTEx will contribute to improving sustainable agriculture-based food systems, comparative biology and eventual human biomedicine.
format	Artículo científico
id	pubmed_40097783
institution	PubMed
language	en
publishDate	2025
publisher	Nature genetics
record_format	pubmed
spellingShingle	The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E Animals Animals, Domestic Genotype Humans Transcriptome Genomics Phenotype The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project. Fang, Lingzhao Teng, Jinyan Lin, Qing Bai, Zhonghao Liu, Shuli Guan, Dailu Li, Bingjie Gao, Yahui Hou, Yali Gong, Mian Pan, Zhangyuan Yu, Ying Clark, Emily L Smith, Jacqueline Rawlik, Konrad Xiang, Ruidong Chamberlain, Amanda J Goddard, Michael E Littlejohn, Mathew Larson, Greger MacHugh, David E O'Grady, John F Sørensen, Peter Sahana, Goutam Lund, Mogens Sandø Jiang, Zhihua Pan, Xiangchun Gong, Wentao Zhang, Haihan He, Xi Zhang, Yuebo Gao, Ning He, Jun Yi, Guoqiang Liu, Yuwen Tang, Zhonglin Zhao, Pengju Zhou, Yang Fu, Liangliang Wang, Xiao Hao, Dan Liu, Lei Chen, Siqian Young, Robert S Shen, Xia Xia, Charley Cheng, Hao Ma, Li Cole, John B Baldwin, Ransom L Li, Cong-Jun Van Tassell, Curtis P Rosen, Benjamin D Bhowmik, Nayan Lunney, Joan Liu, Wansheng Guan, Leluo Zhao, Xin Ibeagha-Awemu, Eveline M Luo, Yonglun Lin, Lin Canela-Xandri, Oriol Derks, Martijn F L Crooijmans, Richard P M A Gòdia, Marta Madsen, Ole Groenen, Martien A M Koltes, James E Tuggle, Christopher K McCarthy, Fiona M Rocha, Dominique Giuffra, Elisabetta Amills, Marcel Clop, Alex Ballester, Maria Tosser-Klopp, Gwenola Li, Jing Fang, Chao Fang, Ming Wang, Qishan Hou, Zhuocheng Wang, Qin Zhao, Fuping Jiang, Lin Zhao, Guiping Zhou, Zhengkui Zhou, Rong Liu, Hehe Deng, Juan Jin, Long Li, Mingzhou Mo, Delin Liu, Xiaohong Chen, Yaosheng Yuan, Xiaolong Li, Jiaqi Zhao, Shuhong Zhang, Yi Ding, Xiangdong Sun, Dongxiao Sun, Hui-Zeng Li, Cong Wang, Yu Jiang, Yu Wu, Dongdong Wang, Wenwen Fan, Xinzhong Zhang, Qin Li, Kui Zhang, Hao Yang, Ning Hu, Xiaoxiang Huang, Wen Song, Jiuzhou Wu, Yang Yang, Jian Wu, Weiwei Kasper, Claudia Liu, Xinfeng Yu, Xiaofei Cui, Leilei Zhou, Xiang Kim, Seyoung Li, Wei Im, Hae Kyung Buckler, Edward S Ren, Bing Schatz, Michael C Li, Jingyi Jessica Palmer, Abraham A Frantz, Laurent Zhou, Huaijun Zhang, Zhe Liu, George E Animals Animals, Domestic Genotype Humans Transcriptome Genomics Phenotype Genetic mutation and drift, coupled with natural and human-mediated selection and migration, have produced a wide variety of genotypes and phenotypes in farmed animals. We here introduce the Farm Animal Genotype-Tissue Expression (FarmGTEx) Project, which aims to elucidate the genetic determinants of gene expression across 16 terrestrial and aquatic domestic species under diverse biological and environmental contexts. For each species, we aim to collect multiomics data, particularly genomics and transcriptomics, from 50 tissues of 1,000 healthy adults and 200 additional animals representing a specific context. This Perspective provides an overview of the priorities of FarmGTEx and advocates for coordinated strategies of data analysis and resource-sharing initiatives. FarmGTEx aims to serve as a platform for investigating context-specific regulatory effects, which will deepen our understanding of molecular mechanisms underlying complex phenotypes. The knowledge and insights provided by FarmGTEx will contribute to improving sustainable agriculture-based food systems, comparative biology and eventual human biomedicine.
title	The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project.
topic	Animals Animals, Domestic Genotype Humans Transcriptome Genomics Phenotype
url	https://pubmed.ncbi.nlm.nih.gov/40097783/