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| Main Authors: | , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Chemistry & biodiversity
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40133212/ |
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Table of Contents:
- New Curvularin and Norlignanolide Derivatives From Cocultures of Marine Mangrove Endophytic Fungus Penicillium brocae MA-231 and Phytopathogen Curvularia spicifera QA-26. Zhang, Ao-Yuan Shi, Xiao-Shan Wang, Bin-Gui Meng, Ling-Hong Humans Anti-Bacterial Agents Ascomycota Coculture Techniques Density Functional Theory Lignans Microbial Sensitivity Tests Molecular Conformation Molecular Structure Penicillium Rhizophoraceae Zearalenone A new curvularin derivative, curvulone C (1) and a pair of new norlignanolide diastereomers, aspergilfuranone E (2) and 8-epi-aspergilfuranone E (3), together with six known secondary metabolites (4-9) were isolated and identified from the coculture of the marine mangrove endophytic fungus Penicillium brocae MA-231 and phytopathogen Curvularia spicifera QA-26. Their structures were elucidated on the basis of spectroscopic analysis, and the absolute configurations were assigned on the basis of time-dependent density functional theory-electronic circular dichroism calculations. Compounds 1 and 4 showed inhibitory activities against several human and aquatic pathogens.