Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Zhang, Shanshan, Chen, Na, Wu, Faji, Xu, Xiujin, Zheng, Xiaotong, Cheng, Zhen, Wang, Miaofeng, Wu, Yang, Jiang, Shuoqi, Liu, Qingmei, Liu, Chenfeng, Zhang, Fan, Han, Bingnan
Format:	Artículo científico
Language:	en
Published:	International journal of biological macromolecules 2025
Subjects:	Kv1.3 Potassium Channel Molecular Dynamics Simulation Animals Biological Products Humans Potassium Channel Blockers Structure-Activity Relationship Immune System Diseases Molecular Docking Simulation Drug Discovery
Online Access:	Acceder al recurso
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