Discovery of New Difluorocyclobutyl Derivatives as Effective Glucagon-Like Peptide-1 Receptor Agonists with Reduced hERG Inhibitory Activities.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Miao, Lei, Lou, Jinfang, Xu, Sicong, Zhang, Jinzhu, Zhong, Yongqing, Wang, Guojian, Li, Yuanyuan, Lei, Shaowei, Shao, Shuai, Wang, Jianghai, Huang, Yun, Tang, Xinyi, Ding, Wanjing, Ma, Zhongjun
Format:	Artículo científico
Language:	en
Published:	Journal of medicinal chemistry 2025
Subjects:	Animals Humans Male Mice Blood Glucose Cricetulus Drug Discovery ERG1 Potassium Channel Ether-A-Go-Go Potassium Channels Glucagon-Like Peptide-1 Receptor Glucagon-Like Peptide-1 Receptor Agonists HEK293 Cells Hypoglycemic Agents Piperidines Structure-Activity Relationship Benzimidazoles
Online Access:	Acceder al recurso
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