:: Library Catalog

Imagen de Portada

Guardado en:

Detalles Bibliográficos
Autores principales:	Ying, Ti-Ti, Hu, Hao-Qiang, Wu, Xiao-Wen, Xu, Xu-Liang, Lv, Jian, Zhang, Shu-Ning, Wang, Hong, Hou, Wei, Wei, Bin, Rao, Guo-Wu
Formato:	Artículo científico
Lenguaje:	en
Publicado:	European journal of medicinal chemistry 2025
Materias:	Escherichia coli Structure-Activity Relationship Organoselenium Compounds Glucuronidase Azoles Enzyme Inhibitors Isoindoles Molecular Structure Dose-Response Relationship, Drug Allosteric Regulation Molecular Docking Simulation Stilbenes Glycoproteins
Acceso en línea:	https://pubmed.ncbi.nlm.nih.gov/40168911/
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.
por: Liu, Wandong, et al.
Publicado: (2025)

Structure-Directed Optimization of Ebselen Derivatives as Potent NDM-1 Inhibitors Reverses Meropenem Resistance.
por: Guo, Yan, et al.
Publicado: (2025)

Stereoselective AChE/BChE/BACE1 inhibition by enantiomeric norsesquiterpenoids with an unprecedented oxatricyclo[7.2.1.0]dodecane scaffold from the soft coral Sclerophytum humesi.
por: Luu, Phuong Vu, et al.
Publicado: (2026)

Identification of novel CLK1 inhibitors by computational fragment-based ligand design, co-crystallization, chemical synthesis and structure activity relationships.
por: Bourg, Stéphane, et al.
Publicado: (2026)

Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
por: Chandrasekaran, Vishnupriya, et al.
Publicado: (2025)

Cladophorol-A is an inhibitor of cyclic GMP-AMP synthase.
por: Kissai, Mildred, et al.
Publicado: (2025)

A Cinderella story in antimicrobials: CDPDP's perfect fit for multiple-pathway bacterial inhibition.
por: Ul Hassan, Syed Shams, et al.
Publicado: (2025)

Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
por: Chen, Xiaohui, et al.
Publicado: (2025)

Catalytic Mechanism and Secondary-Structure-Type-Dependent Allosteric Regulation of β-Agarase Amaga.
por: Wang, Xinyi, et al.
Publicado: (2025)

Prediction of newly synthesized heparin mimic's effects as heparanase inhibitor in cancer treatments via variational quantum neural networks.
por: Kocabay, Samet, et al.
Publicado: (2025)

Diverse and Bioactive Lactones from the Sri Lankan Mangrove-Derived Fungus sp. SCSIO41445.
por: Wijerathna, Parakkrama, et al.
Publicado: (2026)

Cytotoxicity, apoptosis, molecular docking, and molecular dynamics study of novel compounds of Sulfamide derivatives coupled with DHP scaffolds as potent inhibitors of the MCF-7, A549, SKOV-3, and EA. yh926 carcinoma cells.
por: Abdulrasool, Amjed, et al.
Publicado: (2026)

Phyllofolactones V-X, Bishomoscalaranes With Proangiogenic and Hypolipidemic Activities From Sponge Phyllospongia foliascens.
por: Hu, Bo, et al.
Publicado: (2025)

Target Screening and Validation of the Antitumor Effect of Saponin Extract From Holothuria leucospilota.
por: Xu, Fuju, et al.
Publicado: (2025)

Synthesis and biological activity of 1H-pyrrolo[3,2-g]isoquinolines as Haspin kinase inhibitors.
por: Malosse, Killian, et al.
Publicado: (2025)

Synthesis and characterization of selenourea-functionalized chitosan derivatives with enhanced antioxidant activity.
por: Wang, Linqing, et al.
Publicado: (2025)

Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition.
por: Tisseur, Lhana, et al.
Publicado: (2025)

Unveiling an indole derivative YM818 as a novel tyrosinase inhibitor with anti-melanogenic and anti-melanin transfer effects.
por: Yang, Chunyan, et al.
Publicado: (2025)

Sirenin and bisabolane sesquiterpenoids from two marine isolates of Penicillium chermesinum with anti-osteoporotic activity by modulating NOD-like receptor signaling pathway.
por: Liu, Yi-Wei, et al.
Publicado: (2025)

Structure-guided discovery of marine natural products as glucokinase activators for type 2 diabetes mellitus: A computational perspective.
por: Krishnakumar, Heyram, et al.
Publicado: (2026)

Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.
por: Zhao, Xue, et al.
Publicado: (2026)

Vanadyl Complexes (VOp-Dmada) Promote Healthy Aging by Regulating Electron Transport Mediated by Mitochondrial Complex II.
por: Wang, Jiayu, et al.
Publicado: (2026)

Robinin Isolated From Solanum Asperum Exhibits Pharmacological Actions in the Central Nervous System of Adult Zebrafish (Danio rerio).
por: Lemos, Cecília Guimarães, et al.
Publicado: (2025)

Talaroindiones A-C, New Polyketides Characterized From the Cold-Seep-Derived Talaromyces indigoticus CS-469.
por: Deng, Ruo-Xi, et al.
Publicado: (2026)

Genome mining of nonenzymatic ortho-quinone methide-based pseudonatural products from ascidian-derived fungus Diaporthe sp.SYSU-MS4722.
por: Ren, Shuya, et al.
Publicado: (2025)

Computational screening of natural plant and marine compounds as potential inhibitors of Mycobacterium tuberculosis dihydrodipicolinate synthase.
por: Meena, Swati, et al.
Publicado: (2026)

Unveiling a pyrroloindoline diketopiperazine biosynthetic pathway featuring a phytoene-synthase-like family prenyltransferase with distinct regioselectivity.
por: Duan, He, et al.
Publicado: (2025)

SMART-assisted discovery of scalaranes from the marine sponge Lendenfeldia sp. and its anti-osteoclastogenesis activity.
por: Pham, Quoc-Vu, et al.
Publicado: (2026)

Genome analysis-led discovery of antimicrobial and herbicidal cytochalasans from the cold-seep-sourced endozoic Curvularia verruculosa CS-129.
por: Hu, Xue-Yi, et al.
Publicado: (2026)

pH-Responsive Nanoscale Mixed Ligand Metal Organic Framework as a Carrier for Photosensitizer in Targeted Antibacterial Photodynamic Therapy.
por: Fasna P H, Fathima, et al.
Publicado: (2025)

New Phthalide Derivatives With Cardioprotective Effects From the Marine Fungus Diaporthe phaseolorum HZ-2.
por: Feng, Ran-Qi, et al.
Publicado: (2026)

Ircindrimanes A-I, nine undescribed meroterpenoids with cytotoxic activities from the marine sponge Ircinia sp.
por: Zhang, Wenjie, et al.
Publicado: (2025)

The Antioxidant Effects of Trypsin-Hydrolysate Derived from Abalone Viscera and Fishery By-Products, and the Angiotensin-I Converting Enzyme (ACE) Inhibitory Activity of Its Purified Bioactive Peptides.
por: Heo, Jun-Ho, et al.
Publicado: (2024)

From Multi-Species Screening to Targeted Investigation: Discovery of ACE Inhibitory Peptides in via Peptidomics, Virtual Screening, and Molecular Dynamics Simulations.
por: Zhang, Haorui, et al.
Publicado: (2026)

Structure-Activity Relationships, Molecular Mechanisms, and Ecotoxicological Evaluation Underlying Nucleoside-Mediated Antifouling Activity.
por: Pereira, Sandra, et al.
Publicado: (2026)

Antifungal phenolic glucosides and related congeners from the cold-seep-derived Talaromyces trachyspermus CS-106.
por: Feng, Xing-Yan, et al.
Publicado: (2026)

Discovery of 4-(2-(methylamino)thiazol-5-yl)pyrimidin-2-amine derivatives as novel cyclin-dependent kinase 12 (CDK12) inhibitors for the treatment of esophageal squamous cell carcinoma.
por: Cao, Yin, et al.
Publicado: (2025)

Discovery of novel thiosemicarbazone dimers as effective inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) for use in cancer therapy.
por: Wang, Lijun, et al.
Publicado: (2026)

Prediction of cytotoxicity of polycyclic aromatic hydrocarbons from first principles.
por: Kim, Taewoo, et al.
Publicado: (2024)

Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi.
por: Luu, Phuong Vu, et al.
Publicado: (2026)