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Jorunnamycin A induces apoptosis in pancreatic ductal adenocarcinoma cells, spheroids, and patient-derived organoids by modulating KRAS-mediated survival pathways.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Khine, Hnin Ei Ei, Suriya, Utid, Rungrotmongkol, Thanyada, Chamni, Supakarn, Lu, Yanxi, Bénard, Alan, Lan, Bin, Mukhopadhyay, Debabrata, Chang, David, Biankin, Andrew, Schneider-Stock, Regine, Grützmann, Robert, Sungthong, Rungroch, Pilarsky, Christian, Chaotham, Chatchai
Format:	Artículo científico
Language:	en
Published:	Scientific reports 2025
Subjects:	Humans Proto-Oncogene Proteins p21(ras) Carcinoma, Pancreatic Ductal Apoptosis Pancreatic Neoplasms Organoids Molecular Docking Simulation Cell Line, Tumor Spheroids, Cellular Antineoplastic Agents Drug Synergism Mutation Cell Survival Signal Transduction
Online Access:	Acceder al recurso
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