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Main Authors:	Wu, Zhisheng, Wang, Yiheng, Chen, Wei-Wei, Sun, Hua, Chen, Xiaoyan, Li, Xiaobo, Wang, Zeshuai, Liang, Weizheng, Wang, Shuang-Yin, Luan, Xuemei, Li, Yijiang, Huang, Shangjin, Liang, Yuteng, Zhang, Jiaqi, Chen, Zhou-Feng, Wang, Guanlin, Gao, Yun, Liu, Yanan, Wang, Jun, Liu, Zhen, Shi, Peng, Liu, Cirong, Lv, Longbao, Hou, Anli, Wu, Chenglin, Yao, Chen, Hong, Zexuan, Dai, Ji, Lu, Zhonghua, Pan, Fan, Chen, Xin, Kettenmann, Helmut, Amit, Ido, Speakman, John R, Chen, Yun, Ginhoux, Florent, Cui, Rongfeng, Huang, Tianwen, Li, Hanjie
Format:	Artículo científico
Language:	en
Published:	Cell 2025
Subjects:	Animals Microglia Neurons Peripheral Nervous System Biological Evolution Phylogeny Mice Cell Size Axons Central Nervous System Vertebrates Macrophages
Online Access:	https://pubmed.ncbi.nlm.nih.gov/40199320/
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Multiple Neuronal Processes, Including the Mauthner Axon, Form a Multi-Axial Fiber Within a Common Myelin Sheath in the Central Nervous System of Adult Lungfishes, Protopterus annectens, Lepidosiren paradoxa, and Neoceratodus forsteri.
by: Zottoli, Steven J, et al.
Published: (2025)

Pathological Features of Vasculitic Neuropathy and the Role of Nerve Biopsy
by: Nan Hu, et al.
Published: (2026)

Genetic and clinical profile of 15 Chinese families with GDAP1‐related Charcot–Marie–Tooth disease and identification of H256R as a frequent mutation
by: Zhongzheng Li, et al.
Published: (2024)

Genetic and Clinical Features of 10 Families With Hereditary Sensory Neuropathies
by: Ke Xu, et al.
Published: (2025)

Human Cytomegalovirus Associated Neuropathies: A Comprehensive Review From Pathophysiology to Clinical and Therapeutic Considerations
by: Naomi Behanan, et al.
Published: (2025)

Association of dynamic hepatic metabolism with clinical outcomes in patients with severe Guillain‐Barré syndrome: A prospective cohort study from multi‐centers in China
by: Jiali Xie, et al.
Published: (2024)

Safety and Cost Analysis of Immunoglobulin Cessation Trials in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
by: Shiwen Koay, et al.
Published: (2025)

Elucidating Causal Associations Between Immune Cells, Circulating Inflammatory Proteins, and Chronic Inflammatory Demyelinating Polyneuropathy: A Two‐Sample Two‐Step Mendelian Randomization Study
by: Ann‐Ching Wang, et al.
Published: (2026)

Unveiling a Regional Variant of Demyelinating Guillain–Barré Syndrome: Nerve Conduction Study Evidence in Bifacial Weakness With Paresthesias
by: Jin Song, et al.
Published: (2026)

Genotype–phenotype correlations of AR‐CMT2S in a cohort of axonal Charcot–Marie–Tooth patients from Central South China
by: Lei Liu, et al.
Published: (2024)

Behavioral Thermoceptive Responses and Morphologic Correlates in Mouse Models of CMT1A , HNPP , and Aging
by: Vaibhav Oberoi, et al.
Published: (2026)

Neuro-toxoplasmosis and fatal necrotizing cerebellitis
by: Gabriele Gaggero
Published: (2022)

Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration
by: Simone Thomas, et al.
Published: (2026)

Identifying Predictors of Idiopathic Small‐Fiber Neuropathy in Adolescent Patients With Chronic Pain
by: William S. Frye, et al.
Published: (2025)

Clinical Diabetic Peripheral Neuropathy: Can It Be Reversed? Arguments for and Against From a NEUROdiab Debate
by: Gordon Sloan, et al.
Published: (2026)

Correction to “Polyneuropathy in Kidney Transplant Recipients: Accuracy of a New Clinical Diagnostic Scoring System”
Published: (2025)

Overall Diagnostic Performance of Multiple Versus Single Physical Examination Tests for the Prediction of Future Diabetic Neuropathy Risk
by: Ethan Parikh, et al.
Published: (2026)

Acquired Transthyretin Amyloidosis in Domino Liver Transplantation Treated With Gene‐Silencers
by: Alessandro Salvalaggio, et al.
Published: (2025)

Do corticosteroids aggravate pure motor chronic inflammatory demyelinating polyneuropathy?
by: Norito Kokubun, et al.
Published: (2024)

Issue Information
Published: (2024)

High‐Fat Diet Disrupt Nerve Function by Targeting Schwann Cells
by: Amanda S. Mondschein, et al.
Published: (2025)

Impact of High‐Dose Tafamidis on Hereditary ATTR ( ATTRv ) Amyloidosis With Central Nervous System Involvement: Two Case Reports With Clinical, Radiological and Cerebrospinal Fluid Follow Up
by: Victor Jia Wei Zhang, et al.
Published: (2025)

Influence of Genomic Ancestry and Other Traditional Risk Factors on the Prevalence of Diabetic Peripheral Neuropathy in Admixed Individuals With Type 1 Diabetes in Brazil: A Pioneer Multicenter Study
by: Cejana Hamu Aguiar, et al.
Published: (2025)

Digenesis in Charcot–Marie–Tooth Disease: Impact of Combined Mutations in the MFN2 and GDAP1 Genes
by: Endrit Shumeri, et al.
Published: (2025)

Ofatumumab for treating autoimmune nodopathy
by: Jianian Hu, et al.
Published: (2025)

Molecular Characterization of Oxaliplatin‐Induced Peripheral Neurotoxicity: The Complex Spectrum of Painful Manifestations
by: Eleonora Pozzi, et al.
Published: (2025)

Significance of Phrenic Nerve Conduction Study in the Electrodiagnosis of G uillain B arré Syndrome
by: Volkan Tasdemir, et al.
Published: (2026)

Measurement of Red Blood Cell Sorbitol Dehydrogenase Activity for Fast Screening of SORD ‐Related Neuropathies
by: Nicholas Moro, et al.
Published: (2026)

Clinical and genetic features of CMT2T in Italian patients confirm the importance of MME pathogenic variants in idiopathic, late‐onset axonal neuropathies
by: Alessandro Geroldi, et al.
Published: (2024)

Dapagliflozin for Small Nerve Fibre Regeneration in Diabetic Peripheral Neuropathy: A Randomised Controlled Study (DINE)
by: Umanath Adhikari, et al.
Published: (2025)

Reply to “Nerve ultrasound as a screening tool for inherited sensory neuronopathy”
by: Alessandro Salvalaggio, et al.
Published: (2024)

Prospective Evaluation of Machine‐Assisted Electrophysiologic and Online Clinical Diagnostic Support Tools in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
by: Michael P. Skolka, et al.
Published: (2025)

Issue Information
Published: (2026)

Broadening the Clinical Spectrum of Axonal Hereditary Neuropathies: A Comparative Case Study on DNAJB2‐ and HINT1‐ Related Disease
by: Bogdan Bjelica, et al.
Published: (2026)

Loss of MEGF10 Decreases the Number of Perisynaptic Schwann Cells and Innervation of Neuromuscular Junctions in Aging Mice
by: Devin Juros, et al.
Published: (2025)

Incidence and risk factors for developing chemotherapy‐induced neuropathic pain in 500 cancer patients: A file‐based observational study
by: Andreas A. Argyriou, et al.
Published: (2024)

Abstracts of the 35th Annual Meeting of the Japanese Peripheral Nerve Society (JPNS)
Published: (2025)

Variability in Conduction Block Definitions Affects the Sensitivity of Diagnostic Criteria for Multifocal Motor Neuropathy
by: Lucas Immich Gonçalves, et al.
Published: (2025)

Issue Information
Published: (2025)

if (filemtime($filename) + $maxlifetime < time()) { unlink($filename); $count++; } } return $count; } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ protected function saveSession($sessId, $data): bool { $sessFile = $this->path . '/sess_' . $sessId; if ($handle = fopen($sessFile, 'w')) { $return = false; // Lock the file for exclusive access to avoid issues with multiple // processes writing session simultaneously: if (flock($handle, LOCK_EX)) { $return = fwrite($handle, $data); // Make sure that there's no trailing data by truncating the file to // the correct length: ftruncate($handle, strlen($data)); fflush($handle); flock($handle, LOCK_UN); } fclose($handle); if ($return !== false) { return true; } } // If we got this far, something went wrong with the file output... // It is tempting to throw an exception here, but this code is called // outside of the context of exception handling, so all we can do is // echo a message.

// Anecdotal testing Today and Yesterday seems to indicate destroy() // is called by the garbage collector and everything is good. // Something to keep in mind though. return 0; } /** * Write function that is called when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ public function write($sessId, $data): bool { if ($this->writesDisabled) { return true; } return $this->saveSession($sessId, $data); } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ abstract protected function saveSession($sessId, $data): bool; }

* * @return void */ public function writeClose() { // The assumption is that we're using PHP's ext/session. // session_write_close() will actually overwrite $_SESSION with an // empty array on completion -- which leads to a mismatch between what // is in the storage object and $_SESSION. To get around this, we // temporarily reset $_SESSION to an array, and then re-link it to // the storage object. // // Additionally, while you _can_ write to $_SESSION following a // session_write_close() operation, no changes made to it will be // flushed to the session handler. As such, we now mark the storage // object isImmutable. $storage = $this->getStorage(); if (! $storage->isImmutable()) { $_SESSION = $storage->toArray(true); session_write_close(); $storage->fromArray($_SESSION); $storage->markImmutable(); } } /** * Attempt to set the session name * * If the session has already been started, or if the name provided fails * validation, an exception will be raised. * * @param string $name * @return SessionManager * @throws Exception\InvalidArgumentException */ public function setName($name) { if ($this->sessionExists()) { throw new Exception\InvalidArgumentException( 'Cannot set session name after a session has already started'

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