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| Main Authors: | , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Molecular therapy. Nucleic acids
2025
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40291378/ |
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| _version_ | 1868266211754639362 |
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| author | Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong |
| author_facet | Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong |
| collection | PubMed - marine biology |
| contents | Looking beyond the origin of SARS-CoV-2: Significant strategic aspects during the five-year journey of COVID-19 vaccine development. Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong It has been five years since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we are also approaching the five-year mark of the COVID-19 pandemic. The vaccine is a significant weapon in combating infectious diseases like SARS-CoV-2. Several vaccines were developed against SARS-CoV-2, and they demonstrated efficacy and safety during these five years. The rapid development of multiple next-generation vaccine candidates in different platforms with very little time is the success story of the vaccine development endeavor. This remarkable success of rapid vaccine development is a new paradigm for fast vaccine development that might help develop infectious diseases and fight against the pandemic. With the completion of five years since the beginning of SARS-CoV-2 origin, we are looking back on the five years and reviewing the milestones, vaccine platforms, animal models, clinical trials, successful collaborations, vaccine safety, real-world effectiveness, and challenges. Lessons learned during these five years will help us respond to public health emergencies and to fight the battle against future pandemics. |
| format | Artículo científico |
| id | pubmed_40291378 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Molecular therapy. Nucleic acids |
| record_format | pubmed |
| spellingShingle | Looking beyond the origin of SARS-CoV-2: Significant strategic aspects during the five-year journey of COVID-19 vaccine development. Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong Looking beyond the origin of SARS-CoV-2: Significant strategic aspects during the five-year journey of COVID-19 vaccine development. Chakraborty, Chiranjib Lo, Yi-Hao Bhattacharya, Manojit Das, Arpita Wen, Zhi-Hong It has been five years since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we are also approaching the five-year mark of the COVID-19 pandemic. The vaccine is a significant weapon in combating infectious diseases like SARS-CoV-2. Several vaccines were developed against SARS-CoV-2, and they demonstrated efficacy and safety during these five years. The rapid development of multiple next-generation vaccine candidates in different platforms with very little time is the success story of the vaccine development endeavor. This remarkable success of rapid vaccine development is a new paradigm for fast vaccine development that might help develop infectious diseases and fight against the pandemic. With the completion of five years since the beginning of SARS-CoV-2 origin, we are looking back on the five years and reviewing the milestones, vaccine platforms, animal models, clinical trials, successful collaborations, vaccine safety, real-world effectiveness, and challenges. Lessons learned during these five years will help us respond to public health emergencies and to fight the battle against future pandemics. |
| title | Looking beyond the origin of SARS-CoV-2: Significant strategic aspects during the five-year journey of COVID-19 vaccine development. |
| url | https://pubmed.ncbi.nlm.nih.gov/40291378/ |