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| Format: | Artículo científico |
| Sprache: | en |
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Transboundary and emerging diseases
2024
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| Online-Zugang: | https://pubmed.ncbi.nlm.nih.gov/40303165/ |
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| author | Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette |
| author_facet | Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette |
| collection | PubMed - marine biology |
| contents | Detection of Tick-Borne Pathogen Coinfections and Coexposures to Foot-and-Mouth Disease, Brucellosis, and Q Fever in Selected Wildlife From Kruger National Park, South Africa, and Etosha National Park, Namibia. Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette Animals Namibia South Africa Animals, Wild Brucellosis Tick-Borne Diseases Q Fever Coinfection Foot-and-Mouth Disease Parks, Recreational Male Female Antelopes Although the rate of emerging infectious diseases that originate in wildlife has been increasing globally in recent decades, there is currently a lack of epidemiological data from wild animals. We used serology to determine prior exposure to foot-and-mouth disease virus (FMDV), spp., and and used genetic testing to detect blood-borne parasitic infections in the genera , , , and from wildlife in two national parks, Kruger National Park (KNP), South Africa, and Etosha National Park (ENP), Namibia. Serum and whole blood samples were obtained from free-roaming plains zebra (), greater kudu (), impala (), and blue wildebeest (). Risk factors (host species, sex, and sampling park) for infection with each pathogen were assessed, as well as the prevalence and distribution of co-occurring infections. In KNP 13/29 (45%; confidence interval [CI]: 26%-64%) kudus tested positive for FMD, but none of these reacted to SAT serotypes. For brucellosis, seropositive results were obtained for 3/29 (10%; CI: 2%-27%) kudu samples. Antibodies against were detected in 6/29 (21%; CI: 8%-40%) kudus, 14/21 (67%; CI: 43%-85%) impalas, and 18/39 (46%; CI: 30%-63%) zebras. A total of 28/28 kudus tested positive for spp. (100%; CI: 88%-100%) and 27/28 for spp. (96%; CI: 82%-100%), whereas 12/19 impalas (63%) and 2/39 zebra (5%) tested positive for . In ENP, only 1/29 (3%; CI: 0%-18%) wildebeest samples tested positive for FMD. None of the samples tested positive for brucellosis, while antibodies were detected in 26/30 wildebeests (87%; CI: 69%-96%), 16/40 kudus (40%; CI: 25%-57%), and 26/26 plains zebras (100%; CI: 87%-100%). A total of 60% spp. and 35% spp. in kudu and 37% wildebeest tested positive to sp. (sable), 30% to , and 3%-7% to spp. The seroprevalence of Q fever was significantly higher in ENP, while spp., , , , and species were significantly higher in KNP. Significant coinfections were also identified. This work provided baseline serological and molecular data on 40+ pathogens in four wildlife species from two national parks in southern Africa. |
| format | Artículo científico |
| id | pubmed_40303165 |
| institution | PubMed |
| language | en |
| publishDate | 2024 |
| publisher | Transboundary and emerging diseases |
| record_format | pubmed |
| spellingShingle | Detection of Tick-Borne Pathogen Coinfections and Coexposures to Foot-and-Mouth Disease, Brucellosis, and Q Fever in Selected Wildlife From Kruger National Park, South Africa, and Etosha National Park, Namibia. Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette Animals Namibia South Africa Animals, Wild Brucellosis Tick-Borne Diseases Q Fever Coinfection Foot-and-Mouth Disease Parks, Recreational Male Female Antelopes Detection of Tick-Borne Pathogen Coinfections and Coexposures to Foot-and-Mouth Disease, Brucellosis, and Q Fever in Selected Wildlife From Kruger National Park, South Africa, and Etosha National Park, Namibia. Cossu, Carlo Andrea Ochai, Sunday Ochonu Troskie, Milana Hartmann, Axel Godfroid, Jacques de Klerk, Lin-Mari Turner, Wendy Kamath, Pauline van Schalkwyk, Ockert Louis Cassini, Rudi Bhoora, Raksha van Heerden, Henriette Animals Namibia South Africa Animals, Wild Brucellosis Tick-Borne Diseases Q Fever Coinfection Foot-and-Mouth Disease Parks, Recreational Male Female Antelopes Although the rate of emerging infectious diseases that originate in wildlife has been increasing globally in recent decades, there is currently a lack of epidemiological data from wild animals. We used serology to determine prior exposure to foot-and-mouth disease virus (FMDV), spp., and and used genetic testing to detect blood-borne parasitic infections in the genera , , , and from wildlife in two national parks, Kruger National Park (KNP), South Africa, and Etosha National Park (ENP), Namibia. Serum and whole blood samples were obtained from free-roaming plains zebra (), greater kudu (), impala (), and blue wildebeest (). Risk factors (host species, sex, and sampling park) for infection with each pathogen were assessed, as well as the prevalence and distribution of co-occurring infections. In KNP 13/29 (45%; confidence interval [CI]: 26%-64%) kudus tested positive for FMD, but none of these reacted to SAT serotypes. For brucellosis, seropositive results were obtained for 3/29 (10%; CI: 2%-27%) kudu samples. Antibodies against were detected in 6/29 (21%; CI: 8%-40%) kudus, 14/21 (67%; CI: 43%-85%) impalas, and 18/39 (46%; CI: 30%-63%) zebras. A total of 28/28 kudus tested positive for spp. (100%; CI: 88%-100%) and 27/28 for spp. (96%; CI: 82%-100%), whereas 12/19 impalas (63%) and 2/39 zebra (5%) tested positive for . In ENP, only 1/29 (3%; CI: 0%-18%) wildebeest samples tested positive for FMD. None of the samples tested positive for brucellosis, while antibodies were detected in 26/30 wildebeests (87%; CI: 69%-96%), 16/40 kudus (40%; CI: 25%-57%), and 26/26 plains zebras (100%; CI: 87%-100%). A total of 60% spp. and 35% spp. in kudu and 37% wildebeest tested positive to sp. (sable), 30% to , and 3%-7% to spp. The seroprevalence of Q fever was significantly higher in ENP, while spp., , , , and species were significantly higher in KNP. Significant coinfections were also identified. This work provided baseline serological and molecular data on 40+ pathogens in four wildlife species from two national parks in southern Africa. |
| title | Detection of Tick-Borne Pathogen Coinfections and Coexposures to Foot-and-Mouth Disease, Brucellosis, and Q Fever in Selected Wildlife From Kruger National Park, South Africa, and Etosha National Park, Namibia. |
| topic | Animals Namibia South Africa Animals, Wild Brucellosis Tick-Borne Diseases Q Fever Coinfection Foot-and-Mouth Disease Parks, Recreational Male Female Antelopes |
| url | https://pubmed.ncbi.nlm.nih.gov/40303165/ |