Imagen de Portada

Portimine A maintains bioactivity following exposure to liver microsomes and cell lysates: no evidence for significant metabolic inactivation.

Fuente: PubMed

Guardado en:

Detalles Bibliográficos
Autores principales:	Brook, Emma M, Helem, Shaya J, McDonald, Charlotte C M, Magon, Nicholas J, Selwood, Andrew I, Harwood, D Tim, Jaiswal, Jagdish K, Hampton, Mark B, Dachs, Gabi U
Formato:	Artículo científico
Lenguaje:	en
Publicado:	Medical oncology (Northwood, London, England) 2025
Materias:	Humans Animals Mice Microsomes, Liver Imines Tandem Mass Spectrometry Cell Survival Cell Line, Tumor Chromatography, Liquid Marine Toxins
Acceso en línea:	Acceder al recurso
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ingrilimine, a novel marine cytotoxic and apoptotic cyclic imine toxin with a high affinity and dual activity on human α7 nicotinic acetylcholine receptor.
por: Delepierre, Muriel, et al.
Publicado: (2026)

Investigating the Effects of Sea Anemone (Stichodactyla haddoni) Toxin on Potassium and Sodium Channel Gene Expression and Cell Death Mechanisms in A549 Cells.
por: Abdollahian, Media, et al.
Publicado: (2026)

Targeting marine jellyfish toxins: development of metalloproteinase inhibitors through a specific method for protease substrate identification.
por: Yu, Chunlin, et al.
Publicado: (2026)

Ranking the cytotoxic potency of Ostreopsis cf. ovata, Ostreopsis cf. siamensis (O. sp. 9), and purified ovatoxins in human keratinocytes.
por: Plessis, Loïc, et al.
Publicado: (2025)

A Fresh Perspective on Cyanobacterial Paralytic Shellfish Poisoning Toxins: History, Methodology, and Toxicology.
por: Smith, Zacharias J, et al.
Publicado: (2025)

Morpho-phylogenetic and toxicological characterisation of Pseudo-nitzschia multiseries from the Sea of Marmara (Türkiye).
por: Sezgin, Rabia, et al.
Publicado: (2025)

First data on tetrodotoxins in Cephalothrix mokievskii (palaeonemertea, nemertea) and possible involvement OF POISONOUS nemerteans in toxification of marine bioresources.
por: Malykin, Grigorii V, et al.
Publicado: (2024)

Proteinaceous Toxins in the Mucus and Proboscis of the Ribbon Worm cf. (Palaeonemertea: Nemertea).
por: Kuznetsov, Vasiliy G, et al.
Publicado: (2025)

Okadaic acid induces oxidative stress and immunotoxicity in zebrafish: involvement of the p53 pathway and behavioral alterations.
por: Chen, Duo, et al.
Publicado: (2026)

Investigation on the inactivation of Prorocentrum lima and degradation of diarrhetic shellfish toxins via peroxymonosulfate-based advanced oxidation process.
por: Mu, Jiahang, et al.
Publicado: (2025)

Aspirin-Inspired 6-O-Carboxymethyl-N-Acetylglucosamine: A potent antitumor agent with enhanced efficacy.
por: Qiao, Ziwen, et al.
Publicado: (2025)

The cytotoxic and hemolytic potential of karmitoxin from Karlodinium armiger and how it interacts with sterols.
por: Prause, Hélène-Christine, et al.
Publicado: (2025)

Reduced myogenic differentiation capacity of satellite cell-derived myoblasts in male ICR mice compared with male C57BL/6 and BALB/c mice.
por: Suzuki, Takahiro, et al.
Publicado: (2026)

Lamprey rescues the block of thymic epithelial cell development in the mouse -deficient thymic rudiment.
por: Morimoto, Ryo, et al.
Publicado: (2025)

Synthesis of some new substituted imines from aldehydes and ketones derived from quinolinic acid
por: Anwar Abdulghani Fathi
Publicado: (2023)

Weathered plastic particles negatively affect mouse primary neurons and glial cells.
por: Shin, Hyun Seung, et al.
Publicado: (2026)

Seasonal and regional variability of lipophilic marine phycotoxins in eutrophic coastal waters of the South China Sea.
por: Liu, Min, et al.
Publicado: (2025)

Advanced 3D biomimetic scaffolds with bioactive glass and bone-conditioned medium for enhanced osteogenesis.
por: Hameed, Shazia, et al.
Publicado: (2025)

Synergistic induction of immunogenic cell death and tumor microenvironment remodeling by biotinylated marine polysaccharide nanoparticles for enhanced colorectal cancer therapy.
por: Wang, Hui, et al.
Publicado: (2026)

The Inhibitory Effect and Mechanism of the Histidine-Rich Peptide rAj-HRP from on Human Colon Cancer HCT116 Cells.
por: Zhang, Yuebin, et al.
Publicado: (2024)

Tissue-specific distribution of cytotoxic triterpene saponins in three Red Sea sea cucumbers.
por: Fayez, Shaimaa, et al.
Publicado: (2026)

A lipidomic approach towards identifying the effects of fragrance hydroperoxides on keratinocytes.
por: Moore, Aaron I, et al.
Publicado: (2025)

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C.
por: Han, Shanhao, et al.
Publicado: (2026)

Detection of Mesenchymal Stem Cell Aging Using an Integrin Mechano-Probe.
por: Liu, Aimei, et al.
Publicado: (2026)

Wound healing effect of fucoidan-loaded gelatin/oxidized carboxymethyl cellulose hydrogel.
por: Jeong, Ji-Won, et al.
Publicado: (2025)

Bacterial Foreignization Nanosystem Elicits Multi-Phenotypic T Cells for Antitumor Immunity.
por: Zhuang, Wan-Ru, et al.
Publicado: (2025)

Marine-Derived Alternariol Suppresses Inflammation by Regulating T Cell Activation and Migration.
por: Liu, Chenfeng, et al.
Publicado: (2025)

Phosphorus-doped yolk-shell carbon nanocages derived from metal-organic frameworks for enhanced magnetic solid-phase extraction of brevetoxins in seawater.
por: Zhou, Jing, et al.
Publicado: (2026)

Fucoidan from Costaria costata alleviated dextran sulfate sodium-induced ulcerative colitis by suppressing dendritic cell activation.
por: Zhang, Wei, et al.
Publicado: (2026)

UV radiation enhanced encapsulation of superparamagnetic iron oxide nanoparticles (MNPs) in microparticles derived from tumor repopulating cells.
por: Liang, Qing-Le, et al.
Publicado: (2024)

Saccharina japonica derived fucoidan potentiates immune checkpoint blockade therapy by modulating the survival and differentiation fate of myeloid-derived suppressor cells.
por: Deng, Zhenzhen, et al.
Publicado: (2026)

Mechanistic insights into antibody recognition of tetrodotoxin analogues: Implications for neurotoxicological assessment.
por: Reverté, Jaume, et al.
Publicado: (2026)

Seasonal monitoring of dissolved and particulate algal biotoxins in the northern Salish Sea using high performance liquid chromatography and tandem mass spectrometry.
por: Ross, Andrew R S, et al.
Publicado: (2025)

Berberine alleviates T cell-driven lung inflammation by inhibiting cytokine secretion and regulating pulmonary microbiota.
por: Ma, Ziqing, et al.
Publicado: (2025)

PSPC1 knockout promotes radiosensitivity, inhibits EMT, and metastasis of nasopharyngeal carcinoma cells.
por: He, Huocong, et al.
Publicado: (2025)

Unveiling the therapeutic role of Vibrio alginolyticus GH5 exopolysaccharide in Alzheimer's disease.
por: Abdelrazik, Mohamad, et al.
Publicado: (2025)

Campylobacter jejuni-derived cytolethal distending toxin promotes colorectal cancer metastasis.
por: He, Zhen, et al.
Publicado: (2024)

Membrane mechanics dictate axonal pearls-on-a-string morphology and function.
por: Griswold, Jacqueline M, et al.
Publicado: (2025)

The Potent Antioxidant 3,5-Dihydroxy-4-Methoxybenzyl Alcohol Reveals Anticancer Activity by Targeting Several Signaling Pathways in Bone Metastatic Human Breast Cancer MDA-MB-231 Cells.
por: Yamaguchi, Masayoshi, et al.
Publicado: (2025)

New Polyhydroxysteroid Glycosides with Antioxidant Activity from the Far Eastern Sea Star .
por: Malyarenko, Timofey V, et al.
Publicado: (2024)