Unveiling the Biotechnological Potential of Cyanobacteria from the Portuguese LEGE-CC Collection Through Lipidomics and Antioxidant and Lipid-Lowering Properties.
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| Format: | Artículo científico |
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Molecules (Basel, Switzerland)
2025
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| author | Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário |
| author_facet | Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário |
| collection | PubMed - marine biology |
| contents | Unveiling the Biotechnological Potential of Cyanobacteria from the Portuguese LEGE-CC Collection Through Lipidomics and Antioxidant and Lipid-Lowering Properties. Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário Cyanobacteria Antioxidants Lipidomics Portugal Animals Fatty Acids Biotechnology Lipids Phylogeny Lipid Metabolism Cyanobacteria are gram-negative prokaryotic microorganisms composed of both broad morphological and phylogenetic diversity inherited from diverse ecosystems like aquatic, terrestrial, or extremophilic environments. In this study, three cyanobacteria strains from the Blue Biotechnology and Ecotoxicology Culture Collection (LEGE-CC) were obtained from different environments in Portugal. Polyphasic analysis was applied for taxonomic identification. The proximate composition analysis indicated the lipid content (6.2% to 9.1% dry weight (DW)), protein content (28.2% to 62.9% DW), and carbohydrate content (19.5% to 46.1% DW). The fatty acid (FA) profiles of the strains revealed the presence of 19 different FAs, with FA 16:0 found in the highest abundance. The lipidomic analysis revealed 230 lipid species, with sp. LEGE 06078 displaying the highest diversity (125 lipid species). These included species-specific and common lipids species that denote biochemical uniqueness that are also carriers of omega-3 FA (-3). Biological assays exhibited strong antioxidant activity against ABTS and DPPH in sp. LEGE 06078, while sp. LEGE 00249 was renowned for reducing lipids in zebrafish larvae. The findings are of immense significance on the lipidomics diversity of cyanobacteria in terms of nutrition, health, and biotechnology, such as addressing obesity and sustainable resource production. |
| format | Artículo científico |
| id | pubmed_40572470 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Molecules (Basel, Switzerland) |
| record_format | pubmed |
| spellingShingle | Unveiling the Biotechnological Potential of Cyanobacteria from the Portuguese LEGE-CC Collection Through Lipidomics and Antioxidant and Lipid-Lowering Properties. Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário Cyanobacteria Antioxidants Lipidomics Portugal Animals Fatty Acids Biotechnology Lipids Phylogeny Lipid Metabolism Unveiling the Biotechnological Potential of Cyanobacteria from the Portuguese LEGE-CC Collection Through Lipidomics and Antioxidant and Lipid-Lowering Properties. Oliveira, Flavio Conde, Tiago Pinho, Marisa Melo, Tânia Hentschke, Guilherme Scotta Urbatzka, Ralph Pereira, Hugo Costa, Monya Vasconcelos, Vitor Domingues, Maria Rosário Cyanobacteria Antioxidants Lipidomics Portugal Animals Fatty Acids Biotechnology Lipids Phylogeny Lipid Metabolism Cyanobacteria are gram-negative prokaryotic microorganisms composed of both broad morphological and phylogenetic diversity inherited from diverse ecosystems like aquatic, terrestrial, or extremophilic environments. In this study, three cyanobacteria strains from the Blue Biotechnology and Ecotoxicology Culture Collection (LEGE-CC) were obtained from different environments in Portugal. Polyphasic analysis was applied for taxonomic identification. The proximate composition analysis indicated the lipid content (6.2% to 9.1% dry weight (DW)), protein content (28.2% to 62.9% DW), and carbohydrate content (19.5% to 46.1% DW). The fatty acid (FA) profiles of the strains revealed the presence of 19 different FAs, with FA 16:0 found in the highest abundance. The lipidomic analysis revealed 230 lipid species, with sp. LEGE 06078 displaying the highest diversity (125 lipid species). These included species-specific and common lipids species that denote biochemical uniqueness that are also carriers of omega-3 FA (-3). Biological assays exhibited strong antioxidant activity against ABTS and DPPH in sp. LEGE 06078, while sp. LEGE 00249 was renowned for reducing lipids in zebrafish larvae. The findings are of immense significance on the lipidomics diversity of cyanobacteria in terms of nutrition, health, and biotechnology, such as addressing obesity and sustainable resource production. |
| title | Unveiling the Biotechnological Potential of Cyanobacteria from the Portuguese LEGE-CC Collection Through Lipidomics and Antioxidant and Lipid-Lowering Properties. |
| topic | Cyanobacteria Antioxidants Lipidomics Portugal Animals Fatty Acids Biotechnology Lipids Phylogeny Lipid Metabolism |
| url | https://pubmed.ncbi.nlm.nih.gov/40572470/ |