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| Main Authors: | , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Molecules (Basel, Switzerland)
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40649315/ |
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| _version_ | 1868266179227811840 |
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| author | Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios |
| author_facet | Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios |
| collection | PubMed - marine biology |
| contents | Comparison of Polyphenolic Content and Bioactivities Between Extracts from the Living Plants and Beach Deposits of the Submerged Brackish Water Angiosperm . Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios Polyphenols Plant Extracts Antioxidants Humans Alismatales Antineoplastic Agents Free Radical Scavengers Bioactive extracts from living plants (LR) and beach deposits (NR) of the submerged brackish water angiosperm were examined for their antioxidant activity and anticancer potential. LR extract scavenged effectively free radicals with IC values of 38.00 μg/mL (DPPH), 12.00 μg/mL (ABTS), 281.00 μg/mL (OH), and 53.00 μg/mL (O), and exhibited reducing activity with an RP value of 37.00 μg/mL. NR extract retained a significant part of LR extract's antioxidant activity by scavenging free radicals with IC values of 180.00 μg/mL (DPPH), 60.00 μg/mL (ABTS), and 164.00 μg/mL (O), and exhibited reducing activity with an RP value of 107.00 μg/mL. Importantly, NR extract (IC value: 60.00 μg/mL) exhibited much higher inhibitory activity than LR extract (IC value: 1100.00 μg/mL) in XTT assay. HPLC analysis revealed that both extracts contained phenolics, such as chicoric acid, quercetin-3--glucopyranoside, -coumaric acid, 3,5-dimethoxy-4-hydroxicinnanic acid, -ferulic acid, and rutin hydrate, possessing antioxidant and/or anticancer activity. Thus, the present study showed for the first time that extracts from either LR or NR are a promising source of bioactive compounds having beneficial properties for human health. |
| format | Artículo científico |
| id | pubmed_40649315 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Molecules (Basel, Switzerland) |
| record_format | pubmed |
| spellingShingle | Comparison of Polyphenolic Content and Bioactivities Between Extracts from the Living Plants and Beach Deposits of the Submerged Brackish Water Angiosperm . Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios Polyphenols Plant Extracts Antioxidants Humans Alismatales Antineoplastic Agents Free Radical Scavengers Comparison of Polyphenolic Content and Bioactivities Between Extracts from the Living Plants and Beach Deposits of the Submerged Brackish Water Angiosperm . Kevrekidou, Alkistis Goutzourelas, Nikolaos Savvidi, Stavroula Trachana, Varvara Assimopoulou, Andreana N Liu, Ming Malea, Paraskevi Stagos, Dimitrios Polyphenols Plant Extracts Antioxidants Humans Alismatales Antineoplastic Agents Free Radical Scavengers Bioactive extracts from living plants (LR) and beach deposits (NR) of the submerged brackish water angiosperm were examined for their antioxidant activity and anticancer potential. LR extract scavenged effectively free radicals with IC values of 38.00 μg/mL (DPPH), 12.00 μg/mL (ABTS), 281.00 μg/mL (OH), and 53.00 μg/mL (O), and exhibited reducing activity with an RP value of 37.00 μg/mL. NR extract retained a significant part of LR extract's antioxidant activity by scavenging free radicals with IC values of 180.00 μg/mL (DPPH), 60.00 μg/mL (ABTS), and 164.00 μg/mL (O), and exhibited reducing activity with an RP value of 107.00 μg/mL. Importantly, NR extract (IC value: 60.00 μg/mL) exhibited much higher inhibitory activity than LR extract (IC value: 1100.00 μg/mL) in XTT assay. HPLC analysis revealed that both extracts contained phenolics, such as chicoric acid, quercetin-3--glucopyranoside, -coumaric acid, 3,5-dimethoxy-4-hydroxicinnanic acid, -ferulic acid, and rutin hydrate, possessing antioxidant and/or anticancer activity. Thus, the present study showed for the first time that extracts from either LR or NR are a promising source of bioactive compounds having beneficial properties for human health. |
| title | Comparison of Polyphenolic Content and Bioactivities Between Extracts from the Living Plants and Beach Deposits of the Submerged Brackish Water Angiosperm . |
| topic | Polyphenols Plant Extracts Antioxidants Humans Alismatales Antineoplastic Agents Free Radical Scavengers |
| url | https://pubmed.ncbi.nlm.nih.gov/40649315/ |