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| Auteurs principaux: | , , |
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| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Trends in biotechnology
2026
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| Sujets: | |
| Accès en ligne: | https://pubmed.ncbi.nlm.nih.gov/40707336/ |
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| _version_ | 1868266174406459393 |
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| author | Li, Jiahui Lau, Cia-Hin Zhu, Haibao |
| author_facet | Li, Jiahui Lau, Cia-Hin Zhu, Haibao Li, Jiahui Lau, Cia-Hin Zhu, Haibao |
| collection | PubMed - marine biology |
| contents | CRISPR/Cas-based personal glucose meters for nucleic acid detection. Li, Jiahui Lau, Cia-Hin Zhu, Haibao CRISPR-Cas Systems Humans Blood Glucose Self-Monitoring Point-of-Care Systems Biosensing Techniques Nucleic Acids Electrochemical Techniques Through integration with clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) systems, personal glucose meters (PGMs) have been repurposed to detect non-glucose targets. PGMs enable the intuitive readout of electrochemical signals, while CRISPR/Cas offers rapid detection and signal amplification capability. Their integration can realize point-of-care (POC) diagnostics. Herein, we critically discuss their advances, pitfalls, and future perspectives. |
| format | Artículo científico |
| id | pubmed_40707336 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Trends in biotechnology |
| record_format | pubmed |
| spellingShingle | CRISPR/Cas-based personal glucose meters for nucleic acid detection. Li, Jiahui Lau, Cia-Hin Zhu, Haibao CRISPR-Cas Systems Humans Blood Glucose Self-Monitoring Point-of-Care Systems Biosensing Techniques Nucleic Acids Electrochemical Techniques CRISPR/Cas-based personal glucose meters for nucleic acid detection. Li, Jiahui Lau, Cia-Hin Zhu, Haibao CRISPR-Cas Systems Humans Blood Glucose Self-Monitoring Point-of-Care Systems Biosensing Techniques Nucleic Acids Electrochemical Techniques Through integration with clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) systems, personal glucose meters (PGMs) have been repurposed to detect non-glucose targets. PGMs enable the intuitive readout of electrochemical signals, while CRISPR/Cas offers rapid detection and signal amplification capability. Their integration can realize point-of-care (POC) diagnostics. Herein, we critically discuss their advances, pitfalls, and future perspectives. |
| title | CRISPR/Cas-based personal glucose meters for nucleic acid detection. |
| topic | CRISPR-Cas Systems Humans Blood Glucose Self-Monitoring Point-of-Care Systems Biosensing Techniques Nucleic Acids Electrochemical Techniques |
| url | https://pubmed.ncbi.nlm.nih.gov/40707336/ |