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Bibliographic Details
Main Authors: Zhao, Yancheng, Jiang, Xiaojing, Jiang, Liming, Wang, Yongjie, Cui, Cuiju, Liu, Xiumei, Li, Zan, Wang, Weijun, Yang, Jianmin
Format: Artículo científico
Language:en
Published: Biology 2025
Online Access:https://pubmed.ncbi.nlm.nih.gov/40723454/
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Table of Contents:
  • Metabolic Alterations in Crassostrea Gigas After Feeding Selenium-Enriched Yeast Based on Transcriptomic Analysis. Zhao, Yancheng Jiang, Xiaojing Jiang, Liming Wang, Yongjie Cui, Cuiju Liu, Xiumei Li, Zan Wang, Weijun Yang, Jianmin This study explores the effects of selenium-enriched yeast supplementation on growth-related and immune-related gene expression in , aiming to support feed optimization in oyster aquaculture. Selenium, an essential trace element, is vital for growth, immune function, and metabolism in animals. Selenium-enriched yeast, an organic form, offers superior bioavailability, enabling efficient absorption and utilization. , a commercially significant marine shellfish, is rich in protein and nutrients, but the effects of selenium on mollusks remain insufficiently explored. In this study, oysters were divided into three groups: a control group without selenium (THNP), a 2 ppm selenium group (THMP), and a 4 ppm selenium group (THHP). Transcriptome sequencing yielded 388,679,026 clean reads. GO and KEGG enrichment analyses identified key metabolic signaling pathways, and a PPI analysis was performed on the translation products of DEGs involved in the KEGG pathways. qRT-PCR validated the expression of principal DEGs. The combined results of enrichment and PPI analyses highlighted pathways such as glutathione metabolism and collagen signaling. Additionally, three hub genes-, , and -were identified as central to the selenium response. These findings enhance the understanding of selenium's molecular impact on oysters and support its application in aquaculture.