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| Main Authors: | , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Analytical and bioanalytical chemistry
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40748359/ |
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Table of Contents:
- Laser-modulated MnBiTe terahertz biosensor for high-sensitivity marine bacterial detection. Hu, Xin Xu, Wenhao Peng, Jing Sun, Baoxin Shao, Zhaoan Song, Qi Zhang, Bingyuan Xuan, Hongzhuan Biosensing Techniques Seawater Limit of Detection Lasers Manganese The prompt and precise identification of marine bacteria is essential for assessing ecosystem health and mitigating microbial contamination in aquatic environments. In this study, we introduce a terahertz (THz) biosensor that utilizes magneto-topological MnBiTe thin films, capitalizing on their quantum anomalous Hall effect and surface-dominated optoelectronic characteristics for label-free bacterial detection. Through the application of surface engineering and laser modulation techniques, the sensor achieves a detection limit of 9.4 CFU/mL for Ruegeria pomeroyi DSS-3, exhibiting adjustable THz photoresponses under ambient conditions. Notably, distinct THz absorption signatures were identified for the bacterial proteins sulfide-quinone oxidoreductase (SQR) and flavocytochrome c subunit B (FccB), with responsivity values ranging from 0.018 to 0.042 A/W at 0.1 THz. Field validation conducted in natural seawater across various latitudes (20-38°N) demonstrated minimal environmental interference (