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Main Authors: Gu, Zihao, Zheng, Rikuan, Sun, Chaomin, Wu, Shimei
Format: Artículo científico
Language:en
Published: Journal of hazardous materials 2025
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Online Access:https://pubmed.ncbi.nlm.nih.gov/40763533/
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author Gu, Zihao
Zheng, Rikuan
Sun, Chaomin
Wu, Shimei
author_facet Gu, Zihao
Zheng, Rikuan
Sun, Chaomin
Wu, Shimei
Gu, Zihao
Zheng, Rikuan
Sun, Chaomin
Wu, Shimei
collection PubMed - marine biology
contents Resistance and removal mechanisms of deep-sea Bacillus sp. A260 in mitigating Mn and microplastic pollution. Gu, Zihao Zheng, Rikuan Sun, Chaomin Wu, Shimei Bacillus Manganese Microplastics Biodegradation, Environmental Water Pollutants, Chemical Biofilms Driven by rapid industrial development, manganese (Mn) and microplastic pollution pose serious threats to aquatic ecosystems and human neurological health, highlighting the urgent need for effective control strategies. Bioremediation has gained increasing attention in recent years owing to its high efficiency and environmentally friendly nature. In this study, we isolated a Mn-resistant strain, Bacillus sp. A260, from deep-sea cold seep sediments. This strain displayed exceptional tolerance to 300 mM Mn and produced significant quantities of manganese carbonate (MnCO). Notably, elevated Mn concentrations promoted biofilm formation by strain A260. Further mechanistic investigations revealed a coordinated regulatory network in Bacillus sp. A260, involving MntR-mediated Mn homeostasis, YkoY/YceF-dependent Mn efflux, and PerR/Fur-regulated Fe/Mn uptake. This network was accompanied by changes in energy metabolism, activation of oxidative stress response, and Spo0A-mediated biofilm synthesis, all of which contributed to the resilience of the strain under Mn stress. In addition, Mn⁺ induced biofilm formation enhanced the microplastic adsorption capacity of strain A260, enabling the simultaneous removal of Mn and microplastics. Strain A260 achieved 97 % Mn and 96 % microplastic removal at pH 7 and 37 ℃ within 14 days, and exhibited strong adaptability to pH and temperature variations. Thus, Bacillus sp. A260 serves as a robust model for studying microbial metal resistance and is a promising candidate for the simultaneous bioremediation of Mn and microplastic contaminants in aquatic environments.
format Artículo científico
id pubmed_40763533
institution PubMed
language en
publishDate 2025
publisher Journal of hazardous materials
record_format pubmed
spellingShingle Resistance and removal mechanisms of deep-sea Bacillus sp. A260 in mitigating Mn and microplastic pollution.
Gu, Zihao
Zheng, Rikuan
Sun, Chaomin
Wu, Shimei
Bacillus
Manganese
Microplastics
Biodegradation, Environmental
Water Pollutants, Chemical
Biofilms
Resistance and removal mechanisms of deep-sea Bacillus sp. A260 in mitigating Mn and microplastic pollution. Gu, Zihao Zheng, Rikuan Sun, Chaomin Wu, Shimei Bacillus Manganese Microplastics Biodegradation, Environmental Water Pollutants, Chemical Biofilms Driven by rapid industrial development, manganese (Mn) and microplastic pollution pose serious threats to aquatic ecosystems and human neurological health, highlighting the urgent need for effective control strategies. Bioremediation has gained increasing attention in recent years owing to its high efficiency and environmentally friendly nature. In this study, we isolated a Mn-resistant strain, Bacillus sp. A260, from deep-sea cold seep sediments. This strain displayed exceptional tolerance to 300 mM Mn and produced significant quantities of manganese carbonate (MnCO). Notably, elevated Mn concentrations promoted biofilm formation by strain A260. Further mechanistic investigations revealed a coordinated regulatory network in Bacillus sp. A260, involving MntR-mediated Mn homeostasis, YkoY/YceF-dependent Mn efflux, and PerR/Fur-regulated Fe/Mn uptake. This network was accompanied by changes in energy metabolism, activation of oxidative stress response, and Spo0A-mediated biofilm synthesis, all of which contributed to the resilience of the strain under Mn stress. In addition, Mn⁺ induced biofilm formation enhanced the microplastic adsorption capacity of strain A260, enabling the simultaneous removal of Mn and microplastics. Strain A260 achieved 97 % Mn and 96 % microplastic removal at pH 7 and 37 ℃ within 14 days, and exhibited strong adaptability to pH and temperature variations. Thus, Bacillus sp. A260 serves as a robust model for studying microbial metal resistance and is a promising candidate for the simultaneous bioremediation of Mn and microplastic contaminants in aquatic environments.
title Resistance and removal mechanisms of deep-sea Bacillus sp. A260 in mitigating Mn and microplastic pollution.
topic Bacillus
Manganese
Microplastics
Biodegradation, Environmental
Water Pollutants, Chemical
Biofilms
url https://pubmed.ncbi.nlm.nih.gov/40763533/