Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Marine pollution bulletin
2025
|
| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40816125/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1868266165130756097 |
|---|---|
| author | Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana |
| author_facet | Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana |
| collection | PubMed - marine biology |
| contents | A marine bacterial strain with polyurethane-degrading activity, a potential for plastic waste control in the oceans. Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana Polyurethanes Zebrafish Biodegradation, Environmental Plastics Animals Water Pollutants, Chemical Oceans and Seas Seawater Plastic pollution represents a significant global challenge, and diverse strategies, including microbial degradation, are needed to address it. This comprehensive study investigated the potential of the novel deep-sea bacterium Stutzerimonas frequens GOM2 to degrade polyurethane (PU), focusing on its ecological safety, including pathogenicity and survival in zebrafish embryo population controls, and the potential for plastic recycling. The marine isolate exhibited the capacity to grow and present clearance halos in functional screenings using two types of commercial water-based dispersions of polyester-PU (Impranil and Polycrylic). The biodegradation of the PU Impranil by the GOM2 strain was subsequently assessed in marine microcosms by monitoring bacterial growth and metabolic activity over time. Physicochemical analyses (including GPC, FTIR, and GC-MS) were used to monitor polymer breakdown by molecular weight loss, changes in functional groups, the disappearance of toxic PU precursors and the appearance of secondary metabolites. GC-MS analysis identified several metabolic intermediates, including plastic and bioplastic precursors, and compounds with potential pharmaceutical applications. Genomic analyses revealed genes encoding enzymes associated with plastic degradation, and the bacterium was found to be nonpathogenic. This strain successfully reversed the embryonic lethality of Impranil in zebrafish via biodegradation of PU, demonstrating the potential for this strain to reduce the toxicity of this plastic. Taken together, our results highlight the potential applicability of S. frequens GOM2 in future biotechnological applications that have significant implications for the blue economy. |
| format | Artículo científico |
| id | pubmed_40816125 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Marine pollution bulletin |
| record_format | pubmed |
| spellingShingle | A marine bacterial strain with polyurethane-degrading activity, a potential for plastic waste control in the oceans. Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana Polyurethanes Zebrafish Biodegradation, Environmental Plastics Animals Water Pollutants, Chemical Oceans and Seas Seawater A marine bacterial strain with polyurethane-degrading activity, a potential for plastic waste control in the oceans. Magaña-Montiel, Nallely Muriel-Millán, Luis Felipe Rojas-Vargas, Jorge Millán-López, Karla Sofía Loza-Tavera, Herminia Schnabel-Peraza, Denhi Peña-Malacara, Carlos Felipe Gracia, Adolfo Pardo-López, Liliana Polyurethanes Zebrafish Biodegradation, Environmental Plastics Animals Water Pollutants, Chemical Oceans and Seas Seawater Plastic pollution represents a significant global challenge, and diverse strategies, including microbial degradation, are needed to address it. This comprehensive study investigated the potential of the novel deep-sea bacterium Stutzerimonas frequens GOM2 to degrade polyurethane (PU), focusing on its ecological safety, including pathogenicity and survival in zebrafish embryo population controls, and the potential for plastic recycling. The marine isolate exhibited the capacity to grow and present clearance halos in functional screenings using two types of commercial water-based dispersions of polyester-PU (Impranil and Polycrylic). The biodegradation of the PU Impranil by the GOM2 strain was subsequently assessed in marine microcosms by monitoring bacterial growth and metabolic activity over time. Physicochemical analyses (including GPC, FTIR, and GC-MS) were used to monitor polymer breakdown by molecular weight loss, changes in functional groups, the disappearance of toxic PU precursors and the appearance of secondary metabolites. GC-MS analysis identified several metabolic intermediates, including plastic and bioplastic precursors, and compounds with potential pharmaceutical applications. Genomic analyses revealed genes encoding enzymes associated with plastic degradation, and the bacterium was found to be nonpathogenic. This strain successfully reversed the embryonic lethality of Impranil in zebrafish via biodegradation of PU, demonstrating the potential for this strain to reduce the toxicity of this plastic. Taken together, our results highlight the potential applicability of S. frequens GOM2 in future biotechnological applications that have significant implications for the blue economy. |
| title | A marine bacterial strain with polyurethane-degrading activity, a potential for plastic waste control in the oceans. |
| topic | Polyurethanes Zebrafish Biodegradation, Environmental Plastics Animals Water Pollutants, Chemical Oceans and Seas Seawater |
| url | https://pubmed.ncbi.nlm.nih.gov/40816125/ |