Image de couverture de livre

TLR4al senses heme as a key damage/danger-associated molecular pattern to activate immune responses in lower vertebrates.

Fuente: PubMed

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Xiong, Ningxia, Lv, Maolin, Zhang, Jingjing, Xu, Yuezong, Tang, Bo, Yang, Chunrong, Su, Jianguo
Format:	Artículo científico
Langue:	en
Publié:	Journal of immunology (Baltimore, Md. : 1950) 2025
Sujets:	Animals Toll-Like Receptor 4 Heme Humans Carps Alarmins Ligands Fish Proteins Lysosomes
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Non-ligand-binding TLR20.2 and dsRNA-binding TLR20.3 form heterodimer for synergistic antiviral response in grass carp.
par: Wang, Pengxu, et autres
Publié: (2026)

La estimulación de TLR, receptores tipo NOD y dectina-1 en neutrófilos humanos induce la producción de citocinas proinflamatorias
par: Jahnnyer Anilio Martínez Moreno
Publié: (2014)

Site-specific methylation of a TLR1 promoter SNP impedes CREB binding to impair antibacterial immunity in grass carp.
par: Lv, Maolin, et autres
Publié: (2026)

Toll-like receptor signaling in teleosts.
par: Su, Jianguo
Publié: (2025)

Recognition Mechanism of RNA by TLR13: Structural Insights and Implications for Immune Activation.
par: Wang, Yibo, et autres
Publié: (2025)

Pathogen-bound C-type lectin and ficolin enhance toll receptor signaling is activated through Spätzle1 cleavage in response to White Spot Syndrome Virus (WSSV) in Penaeusmonodon.
par: Sajith Ahamed, A, et autres
Publié: (2025)

A type III heat shock protein 40 regulates the expression of antimicrobial peptides and hemocyte phagocytosis in Portunus trituberculatus.
par: Zhang, Yi, et autres
Publié: (2025)

Ring Finger protein 34 negatively regulates MyD88-mediated NF-κB signaling via the ubiquitin-proteasome pathway in miiuy croaker (Miichthysmiiuy).
par: Dong, Wenjing, et autres
Publié: (2025)

Rising Star: G Protein-coupled Receptors (GPCRs) in Microenvironment Pharmacology and Sensory Perception Pharmacology.
par: Wang, Jia-Le, et autres
Publié: (2026)

Hidroxicloroquina: Del fármaco de herencia Inca hasta la inmunología moderna
par: Alberto Alfaro-Murillo
Publié: (2020)

pH-Dependent Assembly and Stability of Toll-Like Receptor 3/dsRNA Signaling Complex: Insights from Constant pH Molecular Dynamics and Metadynamics Simulations.
par: Li, Penghui, et autres
Publié: (2025)

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production.
par: Wang, Yang-Yang, et autres
Publié: (2025)

Novel Fusion Protein Based on DR5-Specific TRAIL Variant with Enhanced Antitumor Properties.
par: Yagolovich, Anne V, et autres
Publié: (2025)

Antithrombotic Effect of L. Extract and Its Fractions via Regulating TLRs and the Downstream MAPKs and PI3K/AKT Signaling Pathways in Zebrafish.
par: Wang, Xiyue, et autres
Publié: (2025)

Biosynthetic enzyme analysis identifies a protective role for TLR4-acting gut microbial sulfonolipids in inflammatory bowel disease.
par: Older, Ethan A, et autres
Publié: (2024)

Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways.
par: Huang, Jing, et autres
Publié: (2025)

Characterization of the marine medaka AHRs and the comparison with those of Japanese medaka in response to dioxin and additional AHR ligands.
par: Zhang, Wanglong, et autres
Publié: (2025)

Ketogenic diet attenuates neuroinflammation and restores hippocampal neurogenesis to improve CUMS induced depression-like behavior in mice.
par: Liang, Jinyuan, et autres
Publié: (2025)

Functional characterization of interleukin 17 family members and their receptors in amphioxus.
par: Li, Haifeng, et autres
Publié: (2025)

El papel de la inmunidad innata en la obesidad
par: Ángeles Fortis
Publié: (2012)

Receptores similares a Toll en peces: el inicio de la divergencia
par: IS Rondón-Barragán
Publié: (2009)

Immunomodulatory effects of TAK-242 on osteogenesis of mesenchymal stem cells in acute inflammatory conditions.
par: Ghiasvand, Mahsa, et autres
Publié: (2026)

The NeuroImmunoEndocrine Circuit of Umami Peptides: A Systems Biology Approach.
par: Hemmati, Shiva, et autres
Publié: (2026)

Oral salmon acylated ghrelin increases food intake in common carp (Cyprinus carpio) via ghrelin receptors, likely through sensory nerves rather than systemic absorption.
par: Kihara, Minoru, et autres
Publié: (2026)

Saccharina japonica derived fucoidan potentiates immune checkpoint blockade therapy by modulating the survival and differentiation fate of myeloid-derived suppressor cells.
par: Deng, Zhenzhen, et autres
Publié: (2026)

CXCL20a promotes the immune protection of an inactivated vaccine against grass carp reovirus infection in grass carp (Ctenopharyngodon idella).
par: Lu, Yizhong, et autres
Publié: (2026)

Structural insights into the photochemistry of the LH1-RC complex from the marine purple phototrophic bacterium Rhodovulum sulfidophilum.
par: Yue, Xing-Yu, et autres
Publié: (2026)

Natural ligand 3,3'-diindolylmethane functions as an AHR agonist to modulate angiogenesis and organ development in chicken embryos.
par: Lim, Gee-Yea, et autres
Publié: (2025)

Proteção funcional da enzima heme-oxigenase-1 na lesão renal aguda isquêmica e tóxica
par: Cassiane Dezoti
Publié: (2009)

Fish requires FasL to facilitate CD8+ T-cell function and antimicrobial immunity.
par: Li, Kang, et autres
Publié: (2025)

Papel de los polimorfismos genéticos de los receptores de peaje (Toll-R) en la enfermedad y en el trasplante
par: Zuzet Martínez-Córdova
Publié: (2009)

A modified IL-7 enhances the immune response to an inactivated GCRV-II vaccine in grass carp (Ctenopharyngodon idella).
par: Wang, Shijie, et autres
Publié: (2026)

La revisión por pares en Investigación en Salud
par: HORACIO RIVERA
Publié: (2008)

El modelo del peligro: la importancia de los receptores tipo Toll en la inmunidad innata
par: TEXCA TATEVARI MÉNDEZ LÓPEZ
Publié: (2008)

A comparative analysis of heme vs non-heme iron administration: a systematic review and meta-analysis of randomized controlled trials
par: Gallo Ruelas, Mariano, et autres
Publié: (2025)

Discovery of New Difluorocyclobutyl Derivatives as Effective Glucagon-Like Peptide-1 Receptor Agonists with Reduced hERG Inhibitory Activities.
par: Miao, Lei, et autres
Publié: (2025)

Data-Independent Acquisition-Based Quantitative Proteomics, Nontargeted Metabolomics, and Protein-Ligand Interaction Reveal the Mechanism of Baicalin Inhibiting βhemolytic/cytolytic Activities of .
par: Li, Guihua, et autres
Publié: (2026)

Comprehensive characterization of the interaction between prototypical drug-site markers and multiple sites on human serum albumin by microbore frontal gel chromatography.
par: Yamauchi, Marie, et autres
Publié: (2025)

Hypoxia impairs monocyte/macrophage function and host defense via ALAS2-mediated heme biosynthesis in Japanese sea bass (Lateolabrax japonicus).
par: Fang, Wei-Wei, et autres
Publié: (2026)

Distinct distribution and responses of IgM, IgT1 and IgT2 B cells in common carp.
par: Eltijani, Awatif, et autres
Publié: (2024)