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Main Authors: Hädrich, Maurice, Hoff, Josef, Blombach, Bastian
Format: Artículo científico
Language:en
Published: Metabolic engineering 2025
Subjects:
Online Access:https://pubmed.ncbi.nlm.nih.gov/40834994/
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author Hädrich, Maurice
Hoff, Josef
Blombach, Bastian
author_facet Hädrich, Maurice
Hoff, Josef
Blombach, Bastian
Hädrich, Maurice
Hoff, Josef
Blombach, Bastian
collection PubMed - marine biology
contents Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology. Hädrich, Maurice Hoff, Josef Blombach, Bastian Vibrio Metabolic Engineering Biotechnology The exploitation of Vibrio natriegens as an unconventional host for biotechnology has progressed rapidly. This development is not only a result of the remarkable high growth rate of this marine bacterium on different substrates but is also possible due to good handling properties, a versatile metabolism and its inherent natural competence - features that have facilitated the development of a sophisticated genetic engineering and synthetic biology toolbox. The availability of robust metabolic and regulatory data enables a model-based quantitative description of metabolic routes and accelerates rational metabolic engineering of the facultative anaerobic bacterium. As reviewed here, numerous examples, ranging from small-molecule production over cell-free protein synthesis to bioremediation render V. natriegens a promising next-generation host for biotechnological applications.
format Artículo científico
id pubmed_40834994
institution PubMed
language en
publishDate 2025
publisher Metabolic engineering
record_format pubmed
spellingShingle Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology.
Hädrich, Maurice
Hoff, Josef
Blombach, Bastian
Vibrio
Metabolic Engineering
Biotechnology
Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology. Hädrich, Maurice Hoff, Josef Blombach, Bastian Vibrio Metabolic Engineering Biotechnology The exploitation of Vibrio natriegens as an unconventional host for biotechnology has progressed rapidly. This development is not only a result of the remarkable high growth rate of this marine bacterium on different substrates but is also possible due to good handling properties, a versatile metabolism and its inherent natural competence - features that have facilitated the development of a sophisticated genetic engineering and synthetic biology toolbox. The availability of robust metabolic and regulatory data enables a model-based quantitative description of metabolic routes and accelerates rational metabolic engineering of the facultative anaerobic bacterium. As reviewed here, numerous examples, ranging from small-molecule production over cell-free protein synthesis to bioremediation render V. natriegens a promising next-generation host for biotechnological applications.
title Advances in metabolic engineering of Vibrio natriegens as an unconventional host for biotechnology.
topic Vibrio
Metabolic Engineering
Biotechnology
url https://pubmed.ncbi.nlm.nih.gov/40834994/