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| Main Authors: | , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Trends in microbiology
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40925807/ |
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| _version_ | 1868266154874634241 |
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| author | Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias |
| author_facet | Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias |
| collection | PubMed - marine biology |
| contents | Phage therapy in finfish aquaculture: how to get there? Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias Aquaculture Phage Therapy Fish Diseases Animals Bacteriophages Fishes Bacteria As antimicrobial resistance threatens the future of the aquaculture industry, numerous studies have investigated the use of phages against aquaculture diseases over the past decades. Despite reports of efficient pathogen control, commercial phage solutions are sparse. We discuss limitations of phage therapy and provide suggestions for the progression towards commercially viable solutions. We argue that phage therapy in aquaculture should focus on disease prevention rather than on treatment to reduce the need for antimicrobials. Further, the phage-delivery methods should target the variable pathogen distribution throughout the production chain. Finally, the key challenges of host-specificity and resistance should be tackled by developing predictive tools that can be used to assess phage-pathogen compatibility within a realistic timeframe. |
| format | Artículo científico |
| id | pubmed_40925807 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Trends in microbiology |
| record_format | pubmed |
| spellingShingle | Phage therapy in finfish aquaculture: how to get there? Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias Aquaculture Phage Therapy Fish Diseases Animals Bacteriophages Fishes Bacteria Phage therapy in finfish aquaculture: how to get there? Landor, Lotta A I Ruffo, Valeria Traving, Sachia J Middelboe, Mathias Aquaculture Phage Therapy Fish Diseases Animals Bacteriophages Fishes Bacteria As antimicrobial resistance threatens the future of the aquaculture industry, numerous studies have investigated the use of phages against aquaculture diseases over the past decades. Despite reports of efficient pathogen control, commercial phage solutions are sparse. We discuss limitations of phage therapy and provide suggestions for the progression towards commercially viable solutions. We argue that phage therapy in aquaculture should focus on disease prevention rather than on treatment to reduce the need for antimicrobials. Further, the phage-delivery methods should target the variable pathogen distribution throughout the production chain. Finally, the key challenges of host-specificity and resistance should be tackled by developing predictive tools that can be used to assess phage-pathogen compatibility within a realistic timeframe. |
| title | Phage therapy in finfish aquaculture: how to get there? |
| topic | Aquaculture Phage Therapy Fish Diseases Animals Bacteriophages Fishes Bacteria |
| url | https://pubmed.ncbi.nlm.nih.gov/40925807/ |