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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2025
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/40936099/ |
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Table of Contents:
- CLAE: A High-Fidelity Nanopore Sequencing Strategy for Read-Level Viral Variant Detection and Environmental RNA Virus Discovery. Yu, Hannah Golconda, Sarah Lee, Ga-Eun Xue, Dantong Domínguez-Huerta, Guillermo Wainaina, James M Bolduc, Benjamin Murthy, Shashanka Kim, Shihyoung Faith, Seth Liu, Shan-Lu Lee, Jiyoung Oglesbee, Michael Sullivan, Matthew B Kim, Sanggu Nanopore Sequencing RNA Viruses Nanopores SARS-CoV-2 High-Throughput Nucleotide Sequencing High-fidelity (HF) long-read sequencing enables accurate profiling of microorganisms and pathogens at single-molecule resolution. However, current Oxford Nanopore Technologies (ONT)-a revolutionary platform offering real-time, portable sequencing at relatively low instrumental cost-suffer from severe read-length bias, limited accuracy (often