Imagen de Portada

Marine Natural Product Chagosendine C Induces Cuproptosis in Colorectal Cancer Cells by Targeting FDX1.

Fuente: PubMed

Guardado en:

Detalles Bibliográficos
Autores principales:	Tao, Xiaoyu, Wang, Hongru, Wang, Qun, Wang, Chengji, Shao, Chang-Wei, Jin, Yang, Yu, Dianping, Hu, Hongmei, Zhang, Qing, Xu, Mengting, Geng, Xiangxin, Xu, Hanchi, Li, Linyang, Shen, Ruling, Guo, Yue-Wei, Li, Xu-Wen, Liu, Sanhong, Zhang, Weidong
Formato:	Artículo científico
Lenguaje:	en
Publicado:	Journal of the American Chemical Society 2025
Materias:	Humans Colorectal Neoplasms Antineoplastic Agents Animals Mice Copper Biological Products Cell Proliferation Drug Screening Assays, Antitumor Cell Line, Tumor Molecular Structure Apoptosis
Acceso en línea:	Acceder al recurso
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Aspirin-Inspired 6-O-Carboxymethyl-N-Acetylglucosamine: A potent antitumor agent with enhanced efficacy.
por: Qiao, Ziwen, et al.
Publicado: (2025)

Preparation of mitochondria-targeted camptothecin derivatives for the imaging and antiproliferation of colorectal cancer.
por: Xu, Chenmeng, et al.
Publicado: (2025)

Integrating experimental findings and machine learning models to predict the anticancer potential of newly synthesized oversulfated fucoidan.
por: Kocabay, Samet, et al.
Publicado: (2026)

Design and Synthesis of Marine Sarocladione Derivatives with Potential Anticancer Activity.
por: Liu, Xiao-Mei, et al.
Publicado: (2026)

The Inhibitory Effect and Mechanism of the Histidine-Rich Peptide rAj-HRP from on Human Colon Cancer HCT116 Cells.
por: Zhang, Yuebin, et al.
Publicado: (2024)

Synthesis of mitochondria-targeted podophyllotoxin derivatives for the imaging and antiproliferation of liver cancer.
por: Xu, Chenmeng, et al.
Publicado: (2026)

Chemical Evolution of Aplithianine Class of Serine/Threonine Kinase Inhibitors.
por: Du, Lin, et al.
Publicado: (2025)

Anticancer Effects of Monacolin X Against Human Liver Cancer Cell Line: Exploring the Apoptosis Using AO/EB and DCFHDA Fluorescent Staining.
por: Jayaraman, Vennila, et al.
Publicado: (2025)

Tumor Microenvironment-Responsive Multinucleated Nanocomplexes Loaded with Carbon Dots for Combined Photothermal/Chemodynamic Therapy of Breast Cancer.
por: Zhu, Zihan, et al.
Publicado: (2025)

Discovery of novel thiosemicarbazone dimers as effective inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) for use in cancer therapy.
por: Wang, Lijun, et al.
Publicado: (2026)

FL496, an FL118-derived small molecule, induces growth inhibition, senescence, and apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrexed-cisplatin combination.
por: Aljahdali, Ieman A M, et al.
Publicado: (2025)

Structure-Activity Relationship Study of Majusculamide D: Overcoming Metabolic Instability and Severe Toxicity with a Fluoro Analogue.
por: Zhao, Xiuhe, et al.
Publicado: (2024)

Total syntheses of Kavaratamide A and 5--Kavaratamide A.
por: Ren, Tieshun, et al.
Publicado: (2025)

Cytotoxicity, apoptosis, molecular docking, and molecular dynamics study of novel compounds of Sulfamide derivatives coupled with DHP scaffolds as potent inhibitors of the MCF-7, A549, SKOV-3, and EA. yh926 carcinoma cells.
por: Abdulrasool, Amjed, et al.
Publicado: (2026)

Discovery of an orally bioavailable pyridone-based BRD4 inhibitor with potent antitumor efficacy in colorectal cancer.
por: Fang, Zhangyun, et al.
Publicado: (2026)

Oxalicpyridones A-D, 2-pyridone alkaloids from a marine-derived fungus Penicillium oxalicum suppressing proliferation and metastasis against small cell lung cancer.
por: Chen, Xiangliu, et al.
Publicado: (2026)

Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi.
por: Luu, Phuong Vu, et al.
Publicado: (2026)

Shimojilide, a Potent and Selective Antiproliferative Cyclic Lipopeptide from a Marine Cyanobacterium sp.
por: Niiyama, Mizuho, et al.
Publicado: (2026)

Prediction of newly synthesized heparin mimic's effects as heparanase inhibitor in cancer treatments via variational quantum neural networks.
por: Kocabay, Samet, et al.
Publicado: (2025)

Discovery of 4-(2-(methylamino)thiazol-5-yl)pyrimidin-2-amine derivatives as novel cyclin-dependent kinase 12 (CDK12) inhibitors for the treatment of esophageal squamous cell carcinoma.
por: Cao, Yin, et al.
Publicado: (2025)

Identification of EEF1A1 as a therapeutic target in TNBC: Anticancer action of a novel Penicillide-derived inhibitor through ribosomal protein regulation.
por: Yu, Jing, et al.
Publicado: (2026)

Target Screening and Validation of the Antitumor Effect of Saponin Extract From Holothuria leucospilota.
por: Xu, Fuju, et al.
Publicado: (2025)

Pyrimidine Nucleosides, Benzoic Acid Derivative, and Bipyridine From the Marine-Derived Streptomyces Sp. DS52.
por: Xia, Meng-de, et al.
Publicado: (2025)

Ircindrimanes A-I, nine undescribed meroterpenoids with cytotoxic activities from the marine sponge Ircinia sp.
por: Zhang, Wenjie, et al.
Publicado: (2025)

Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
por: Chen, Xiaohui, et al.
Publicado: (2025)

Novel Marine Fungus-Derived Mycophenolic Acids That Inhibit Acute Myeloid Leukemia Cell Proliferation.
por: Deng, Guangli, et al.
Publicado: (2026)

Metabolic Blockade-Based Genome Mining of SCSIO 07745: Discovery and Biosynthetic Pathway of Aminoquinolinone Alkaloids Bearing 6/6/5 Tricyclic and 6/6/6/5 Tetracyclic Scaffolds.
por: Li, Kunlong, et al.
Publicado: (2025)

Bioassay-Guided Procedure Coupled with HR-ESIMS Dereplication for Isolation of Antiproliferative Bromo-Tyramine Derivative from .
por: Esposito, Germana, et al.
Publicado: (2025)

Discovery of the First-in-Class Dual-Target ROCK/HDAC Inhibitor with Potent Antitumor Efficacy in Vivo That Trigger Antitumor Immunity.
por: Mao, Churu, et al.
Publicado: (2024)

Total Synthesis of Nocarterphenyl A, 2-Dehydroxymethylnocarterphenyl A and Nocarterphenyl D Produced by Marine spp.
por: Xu, Quan, et al.
Publicado: (2025)

PPTase-Based Activation Unlocks New Anthraquinones from Marine-Derived sp. SCSIO 07396.
por: Li, Xiaohua, et al.
Publicado: (2026)

Candindoles A and B, Heterozygous Terphenyl-Indole Alkaloids with Antifungal and Cytotoxic Activities from the Marine-Derived Fungus HNNU0546.
por: Liu, Yi-Yi, et al.
Publicado: (2025)

Antimicrobial and anticancer activity of Streptomyces ambofaciens (Myt 8) and S. globisporus ONU 1019 (Myt 11) secondary metabolites isolated from the Odesa Bay, the Black Sea: An in vitro study.
por: Potapenko, Kateryna, et al.
Publicado: (2025)

Undescribed alkaloids, peptides and polyketides from marine sediment-derived fungus Aspergillus terreus PPS1.
por: Zheng, Yao-Yao, et al.
Publicado: (2025)

Immunocompetent tumor-on-a-chip: A translational tool for drug screening and cancer therapy.
por: Liang, Anqi, et al.
Publicado: (2025)

Suaeglaucin C: a new coumaronochromone isolated from .
por: Jia, Jia, et al.
Publicado: (2026)

Geodiamolide A, a Marine Sponge Depsipeptide, Halts Proliferation and Triggers Cell Death in Squamous Cell Carcinoma (A431, NMSC) In Vitro.
por: Rangel, Marisa, et al.
Publicado: (2026)

Activation of the γ-secretase/NICD-PXR/Notch pathway induces Taxol resistance in triple-negative breast cancer.
por: Wang, Zuo-Jun, et al.
Publicado: (2024)

Antibacterial and Cytotoxic Decahydrofluorene-Class Alkaloids from the Marine-Derived Fungus sp. SCSIO 41512.
por: Ban, Zi-Wei, et al.
Publicado: (2026)

Biogenic gold nanoparticles synthesized from Caulerpa sertularioides: A green approach for antioxidant, antibacterial and anticancer applications.
por: Sivakumar, Vibitha Sri, et al.
Publicado: (2025)