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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Biology
2025
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41007275/ |
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Table of Contents:
- Study on the Antagonistic Bacterium in the Gut Microbiota of . Xu, Shiwei Chen, Qi Liu, Anna Chen, Shu Chen, Wanyi Qian, Shixin Wang, Lei Chen, Yihong The present study investigates the gut microbiota dynamics of during infection and identifies potential probiotic candidates for disease control in aquaculture. We artificially infected with and analyzed the gut microbiota of dying fish, asymptomatic fish during the peak mortality period, and healthy fish. The results showed that infection significantly altered the gut microbiota diversity. Based on analysis of gut microorganisms, we isolated and identified an -resistant from the gut of , which was named MS05 (BaMS05). BaMS05 demonstrated significant antibacterial activity against and other common pathogens of both in vitro and in vivo. Additionally, BaMS05 could colonize the gut of for at least five days and exhibited a protective effect against infection, reducing cumulative mortality by 40% at the fifth day. This study provides insights into the role of gut microbiota in disease resistance and highlights BaMS05 as a potential probiotic for preventing and controlling infections in aquaculture. Further research will focus on optimizing the application of BaMS05 and verifying its biosafety for practical use in farming.