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Main Authors: Dinh-Hung, Nguyen, Khang, Luu Tang Phuc, Wisetkaeo, Suwanna, Tran, Ngoc Tuan, Po-Tsang, Lee, Brown, Christopher L, Sangsawad, Papungkorn, Dwinanti, Sefti Heza, Permpoonpattana, Patima, Linh, Nguyen Vu
Format: Artículo científico
Language:en
Published: Biology 2025
Online Access:https://pubmed.ncbi.nlm.nih.gov/41007305/
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author Dinh-Hung, Nguyen
Khang, Luu Tang Phuc
Wisetkaeo, Suwanna
Tran, Ngoc Tuan
Po-Tsang, Lee
Brown, Christopher L
Sangsawad, Papungkorn
Dwinanti, Sefti Heza
Permpoonpattana, Patima
Linh, Nguyen Vu
author_facet Dinh-Hung, Nguyen
Khang, Luu Tang Phuc
Wisetkaeo, Suwanna
Tran, Ngoc Tuan
Po-Tsang, Lee
Brown, Christopher L
Sangsawad, Papungkorn
Dwinanti, Sefti Heza
Permpoonpattana, Patima
Linh, Nguyen Vu
Dinh-Hung, Nguyen
Khang, Luu Tang Phuc
Wisetkaeo, Suwanna
Tran, Ngoc Tuan
Po-Tsang, Lee
Brown, Christopher L
Sangsawad, Papungkorn
Dwinanti, Sefti Heza
Permpoonpattana, Patima
Linh, Nguyen Vu
collection PubMed - marine biology
contents Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture. Dinh-Hung, Nguyen Khang, Luu Tang Phuc Wisetkaeo, Suwanna Tran, Ngoc Tuan Po-Tsang, Lee Brown, Christopher L Sangsawad, Papungkorn Dwinanti, Sefti Heza Permpoonpattana, Patima Linh, Nguyen Vu Caffeic acid (CA), a plant-derived phenolic compound, is emerging as a promising natural feed additive for sustainable aquaculture. Its growth-promoting, immunomodulatory, and antimicrobial activities suggest utility as an alternative that diminishes antibiotic use in fish farming. Evidence across multiple species indicates improvements in innate immune responses, enhanced antioxidant capacity, and increased survival during pathogen challenge. Nevertheless, adoption remains limited by unresolved questions regarding optimal inclusion levels, species-specific physiological responses, interactions with other dietary components, and effects on the gut microbiota. This review synthesizes current research on CA, critically evaluates its functional roles in aquaculture, and assesses its relevance to sustainable production. Priorities for future work include elucidating mechanisms of action, conducting cross-species dose-response studies, standardizing dosing protocols, clarifying microbiome effects, and evaluating economic feasibility for large-scale use. Addressing these gaps will be essential to realize the full potential of CA as a functional feed additive in sustainable aquaculture systems.
format Artículo científico
id pubmed_41007305
institution PubMed
language en
publishDate 2025
publisher Biology
record_format pubmed
spellingShingle Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture.
Dinh-Hung, Nguyen
Khang, Luu Tang Phuc
Wisetkaeo, Suwanna
Tran, Ngoc Tuan
Po-Tsang, Lee
Brown, Christopher L
Sangsawad, Papungkorn
Dwinanti, Sefti Heza
Permpoonpattana, Patima
Linh, Nguyen Vu
Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture. Dinh-Hung, Nguyen Khang, Luu Tang Phuc Wisetkaeo, Suwanna Tran, Ngoc Tuan Po-Tsang, Lee Brown, Christopher L Sangsawad, Papungkorn Dwinanti, Sefti Heza Permpoonpattana, Patima Linh, Nguyen Vu Caffeic acid (CA), a plant-derived phenolic compound, is emerging as a promising natural feed additive for sustainable aquaculture. Its growth-promoting, immunomodulatory, and antimicrobial activities suggest utility as an alternative that diminishes antibiotic use in fish farming. Evidence across multiple species indicates improvements in innate immune responses, enhanced antioxidant capacity, and increased survival during pathogen challenge. Nevertheless, adoption remains limited by unresolved questions regarding optimal inclusion levels, species-specific physiological responses, interactions with other dietary components, and effects on the gut microbiota. This review synthesizes current research on CA, critically evaluates its functional roles in aquaculture, and assesses its relevance to sustainable production. Priorities for future work include elucidating mechanisms of action, conducting cross-species dose-response studies, standardizing dosing protocols, clarifying microbiome effects, and evaluating economic feasibility for large-scale use. Addressing these gaps will be essential to realize the full potential of CA as a functional feed additive in sustainable aquaculture systems.
title Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture.
url https://pubmed.ncbi.nlm.nih.gov/41007305/