Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters.
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| Autores principales: | , , , , , , |
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| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Scientific data
2025
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| _version_ | 1868266146710421504 |
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| author | Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li |
| author_facet | Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li |
| collection | PubMed - marine biology |
| contents | Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters. Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li Animals Fatty Acids, Omega-3 Crassostrea Polymorphism, Single Nucleotide Transcriptome Genome-Wide Association Study This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3ω3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying ω-3 fatty acid dynamics, enabling future investigations into sustainable marine resource utilization and climate resilience. |
| format | Artículo científico |
| id | pubmed_41022887 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Scientific data |
| record_format | pubmed |
| spellingShingle | Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters. Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li Animals Fatty Acids, Omega-3 Crassostrea Polymorphism, Single Nucleotide Transcriptome Genome-Wide Association Study Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters. Li, Qingyuan Cong, Rihao Wang, Chaogang Wang, Wei Zhang, Guofan Qi, Haigang Li, Li Animals Fatty Acids, Omega-3 Crassostrea Polymorphism, Single Nucleotide Transcriptome Genome-Wide Association Study This data descriptor presents a multi-omics resource for Crassostrea gigas and Crassostrea angulata, comprising genomic variants and transcriptomic profiles relevant to fatty acid metabolism traits. A 458-individual F hybrid population genotyped with a 100 K SNP array identified 344 SNPs and 742 candidate genes linked to C18:3ω3, EPA, and DHA variation. KEGG analysis highlighted 24 key genes, with 23 validated via GS-assisted GWAS, dominant genotype screening, and wild population resequencing. Differential expression analysis revealed 458 DEGs (266 between high/low EPA + DHA groups; 192 between species), overlapping with 152 genes from GWAS and selective sweeps. This integrated dataset provides foundational genetic references for studying ω-3 fatty acid dynamics, enabling future investigations into sustainable marine resource utilization and climate resilience. |
| title | Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters. |
| topic | Animals Fatty Acids, Omega-3 Crassostrea Polymorphism, Single Nucleotide Transcriptome Genome-Wide Association Study |
| url | https://pubmed.ncbi.nlm.nih.gov/41022887/ |