Comparative study of mortalities, clinical manifestations, antioxidant-associated genes, and histopathological degeneration upon experiment infection by in and .
Fuente:
PubMed
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Open veterinary journal
2025
|
| Sujets: | |
| Accès en ligne: | |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
| _version_ | 1868266144202227713 |
|---|---|
| author | Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M |
| author_facet | Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M |
| collection | PubMed - marine biology |
| contents | Comparative study of mortalities, clinical manifestations, antioxidant-associated genes, and histopathological degeneration upon experiment infection by in and . Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M Animals Aeromonas hydrophila Gram-Negative Bacterial Infections Fish Diseases Carps Cichlids Antioxidants is a pathogenic bacterial infection threatening the aquaculture industry. The current work was performed to scrutinize the impacts of infection on the occurrence of mortalities, altering the clinical picture of fish, antioxidants-associated gene expression, and histopathological architecture of the and . Juvenile fishes including , = 60, and , = 60 were haphazardly alienated into the control group (uninfected) and infected group with 100 μl of . Mortalities and clinical signs were recorded during the experiment. Samples of liver, kidney, and spleen were collected post-infection for 7 days to monitor the expression of superoxide dismutase, glutathione peroxidase, and catalase genes, plus the assessment of histopathology. The rate of mortalities was higher in compared to . Additionally, infected revealed red eyes and erythema, while showed exophthalmia and severe skin ulceration with exposure to viscera. The gene expression indicators showed that significantly declined on the 1st day and the 7th day after infection, but significantly increased ( < 0.05) on the 3rd day compared to their respective control groups for . Meanwhile, significantly regulated gene expression ( < 0.05) in the control groups. The histological picture indicated that the liver is the most affected organ. Moreover, exhibited more disruption in histological architecture related to . Overall, is extremely virulent and results in higher mortalities, profound clinical manifestations, down-regulation in the gene expression, and histopathological alterations in the hepato-renal and splenic tissues of and was more adversely affected by the infection compared to However, revealed higher gene expression, particularly in the spleen, and the genes were more expressed in comparison to . |
| format | Artículo científico |
| id | pubmed_41036338 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | Open veterinary journal |
| record_format | pubmed |
| spellingShingle | Comparative study of mortalities, clinical manifestations, antioxidant-associated genes, and histopathological degeneration upon experiment infection by in and . Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M Animals Aeromonas hydrophila Gram-Negative Bacterial Infections Fish Diseases Carps Cichlids Antioxidants Comparative study of mortalities, clinical manifestations, antioxidant-associated genes, and histopathological degeneration upon experiment infection by in and . Al-Shammari, Nadia A H Al-Niaeem, Khalidah S Al-Hawash, Adnan B Abomughaid, Mosleh Mohammad Abdelazim, Aaser M Elumalai, Preetham Eissa, El-Sayed Hemdan Mahboub, Heba H Elbaghdady, Heba Allah M Animals Aeromonas hydrophila Gram-Negative Bacterial Infections Fish Diseases Carps Cichlids Antioxidants is a pathogenic bacterial infection threatening the aquaculture industry. The current work was performed to scrutinize the impacts of infection on the occurrence of mortalities, altering the clinical picture of fish, antioxidants-associated gene expression, and histopathological architecture of the and . Juvenile fishes including , = 60, and , = 60 were haphazardly alienated into the control group (uninfected) and infected group with 100 μl of . Mortalities and clinical signs were recorded during the experiment. Samples of liver, kidney, and spleen were collected post-infection for 7 days to monitor the expression of superoxide dismutase, glutathione peroxidase, and catalase genes, plus the assessment of histopathology. The rate of mortalities was higher in compared to . Additionally, infected revealed red eyes and erythema, while showed exophthalmia and severe skin ulceration with exposure to viscera. The gene expression indicators showed that significantly declined on the 1st day and the 7th day after infection, but significantly increased ( < 0.05) on the 3rd day compared to their respective control groups for . Meanwhile, significantly regulated gene expression ( < 0.05) in the control groups. The histological picture indicated that the liver is the most affected organ. Moreover, exhibited more disruption in histological architecture related to . Overall, is extremely virulent and results in higher mortalities, profound clinical manifestations, down-regulation in the gene expression, and histopathological alterations in the hepato-renal and splenic tissues of and was more adversely affected by the infection compared to However, revealed higher gene expression, particularly in the spleen, and the genes were more expressed in comparison to . |
| title | Comparative study of mortalities, clinical manifestations, antioxidant-associated genes, and histopathological degeneration upon experiment infection by in and . |
| topic | Animals Aeromonas hydrophila Gram-Negative Bacterial Infections Fish Diseases Carps Cichlids Antioxidants |
| url | https://pubmed.ncbi.nlm.nih.gov/41036338/ |