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| Hauptverfasser: | , , |
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| Format: | Artículo científico |
| Sprache: | en |
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Open veterinary journal
2025
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| Schlagworte: | |
| Online-Zugang: | https://pubmed.ncbi.nlm.nih.gov/41036368/ |
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Inhaltsangabe:
- Antibacterial activity of marine microalgae extracts against pathogen of Siamese fighting fish (). Manklinniam, Piyapan Phunpruch, Saranya Worananthakij, Worakrit Animals Anti-Bacterial Agents Microalgae Microbial Sensitivity Tests Fish Diseases Plant Extracts Gas Chromatography-Mass Spectrometry Chlorella Bacteria Marine microalgae extracts are a promising alternative to commercial drugs because of their antimicrobial properties. This study aimed to investigate the antibacterial properties of crude extracts containing bioactive compounds derived from sp., , and . Crude extracts from microalgae were obtained via maceration using ethanol and hexane as solvents. Antibacterial activities were initially screened using the agar well diffusion method, whereas antimycobacterial activity was assessed using the microplate 7H11 agar proportion method. Subsequently, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the crude extracts were determined. Gas chromatography-mass spectrometry (GC-MS) was used for phytochemical composition analysis to identify significant antimicrobial compounds in the extracts. The ethanolic extract of demonstrated detectable antibacterial activity, with an inhibition zone of 12.40 ± 0.06 mm against , 12.22 ± 0.28 mm against , 11.10 ± 0.11 mm against , and 10.99 ± 0.33 mm against at 100 mg/ml. Extracts from and inhibited , suggesting potential benefits for betta fish health. MIC values were 25 mg/ml for in the ethanolic extracts of , , sp., and hexane extract. The GC-MS chromatogram of the ethanolic extract of revealed the presence of several bioactive compounds. The major components identified include Phthalate, Tetradecanoic acid, Hexadecanoic acid, and Phytol. This study demonstrated the promising antimicrobial potential of crude extracts from marine microalgae, particularly the ethanolic extract of , which showed strong activity against both terrestrial and aquatic pathogens. The findings suggest that bioactive compounds in these extracts, especially those from and , can be effective in managing bacterial infections such as and in betta fish. These results highlight the potential of marine microalgae as natural, sustainable alternatives for disease control in aquaculture.