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| Format: | Artículo científico |
| Sprache: | en |
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BMC microbiology
2025
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| Online-Zugang: | https://pubmed.ncbi.nlm.nih.gov/41039239/ |
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| author | Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua |
| author_facet | Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua |
| collection | PubMed - marine biology |
| contents | Vibrio spp.: a potential critical pathogen for mammals with implications beyond marine aquaculture. Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua Animals Vibrio RNA, Ribosomal, 16S Aquaculture Vibrio Infections Bacteria Microbiota Phylogeny Whales Gastrointestinal Microbiome Skin Mammals Species-specific or health status specific microbiome composition of cetaceans is still poorly classified due to the limited samples. Despite a partial identification of the gut microbiota of melon-headed whales (Peponocephala electra), comparative analyses across anatomical systems are lacking. This study provides the first comprehensive analysis of the microbial communities habiting nine body sites - oral cavity, esophagus, foregut, midgut, hindgut, blowhole, and skin wounds (left anterior, dorsal fin, tail) - in a stranded melon-headed whale. By 16 S rRNA gene sequencing, a decrease in microbial richness was observed from the oral cavity to the hindgut, accompanied by compositional shifts from Fusobacterium-dominated oral/esophageal niches to Vibrio-enriched gastrointestinal regions (21.81% Vibrio, 21.19% Fusobacterium, 12.50% Actinobacillus). The respiratory tract microbiota underwent a significant shift and was dominated by Ostreibacterium (57.5%), Helcococcus (6.59%), and Tenacibaculum (4.12%). Skin wounds showed environmental similarities, with Vibrio (47.84%), Pseudoalteromonas (17.84%), and Psychrobacter (12.36%). Pan-microbiome screening identified seven Vibrio species (V. alginolyticus, V. cidicii, V. cyclitrophicus, V. navarrensis, V. parahaemolyticus, V. salilacus, and V. splendidus) across all niches, along with V. cholerae in non-respiratory samples. Notably, V. profundi was exclusively localized to anterior and dorsal fin wounds. Functional profiling revealed enrichment of Vibrio-linked pathogenesis pathways (infection, pathogenic cycle) and metabolic modules that were correlated with immunocompromised states. This study revealed significant bidirectional environment-host microbiome exchange dynamics across cetacean mucosal surfaces. Notably, Vibrio spp. emerged as the dominant genus in both gastrointestinal and cutaneous wound microbiomes, highlighting: (1) potential zoonotic transmission risks from pathogenic Vibrio strains, and (2) the critical need for habitat-specific microbial surveillance to inform marine mammal conservation strategies. |
| format | Artículo científico |
| id | pubmed_41039239 |
| institution | PubMed |
| language | en |
| publishDate | 2025 |
| publisher | BMC microbiology |
| record_format | pubmed |
| spellingShingle | Vibrio spp.: a potential critical pathogen for mammals with implications beyond marine aquaculture. Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua Animals Vibrio RNA, Ribosomal, 16S Aquaculture Vibrio Infections Bacteria Microbiota Phylogeny Whales Gastrointestinal Microbiome Skin Mammals Vibrio spp.: a potential critical pathogen for mammals with implications beyond marine aquaculture. Li, Chengzhang Ji, Yiting Li, Xinying Cai, Jingting Ye, Juntao Wu, Yuqi Liao, Qinghong Wang, Ziyan Sanganyado, Edmond Li, Ping Sun, Yajing Liang, Bo Liu, Wenhua Animals Vibrio RNA, Ribosomal, 16S Aquaculture Vibrio Infections Bacteria Microbiota Phylogeny Whales Gastrointestinal Microbiome Skin Mammals Species-specific or health status specific microbiome composition of cetaceans is still poorly classified due to the limited samples. Despite a partial identification of the gut microbiota of melon-headed whales (Peponocephala electra), comparative analyses across anatomical systems are lacking. This study provides the first comprehensive analysis of the microbial communities habiting nine body sites - oral cavity, esophagus, foregut, midgut, hindgut, blowhole, and skin wounds (left anterior, dorsal fin, tail) - in a stranded melon-headed whale. By 16 S rRNA gene sequencing, a decrease in microbial richness was observed from the oral cavity to the hindgut, accompanied by compositional shifts from Fusobacterium-dominated oral/esophageal niches to Vibrio-enriched gastrointestinal regions (21.81% Vibrio, 21.19% Fusobacterium, 12.50% Actinobacillus). The respiratory tract microbiota underwent a significant shift and was dominated by Ostreibacterium (57.5%), Helcococcus (6.59%), and Tenacibaculum (4.12%). Skin wounds showed environmental similarities, with Vibrio (47.84%), Pseudoalteromonas (17.84%), and Psychrobacter (12.36%). Pan-microbiome screening identified seven Vibrio species (V. alginolyticus, V. cidicii, V. cyclitrophicus, V. navarrensis, V. parahaemolyticus, V. salilacus, and V. splendidus) across all niches, along with V. cholerae in non-respiratory samples. Notably, V. profundi was exclusively localized to anterior and dorsal fin wounds. Functional profiling revealed enrichment of Vibrio-linked pathogenesis pathways (infection, pathogenic cycle) and metabolic modules that were correlated with immunocompromised states. This study revealed significant bidirectional environment-host microbiome exchange dynamics across cetacean mucosal surfaces. Notably, Vibrio spp. emerged as the dominant genus in both gastrointestinal and cutaneous wound microbiomes, highlighting: (1) potential zoonotic transmission risks from pathogenic Vibrio strains, and (2) the critical need for habitat-specific microbial surveillance to inform marine mammal conservation strategies. |
| title | Vibrio spp.: a potential critical pathogen for mammals with implications beyond marine aquaculture. |
| topic | Animals Vibrio RNA, Ribosomal, 16S Aquaculture Vibrio Infections Bacteria Microbiota Phylogeny Whales Gastrointestinal Microbiome Skin Mammals |
| url | https://pubmed.ncbi.nlm.nih.gov/41039239/ |