Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials.
Fuente:
PubMed
Salvato in:
| Autori principali: | , , , , |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Advanced healthcare materials
2026
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1868266144198033408 |
|---|---|
| author | Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick |
| author_facet | Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick |
| collection | PubMed - marine biology |
| contents | Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials. Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick Animals Recombinant Proteins Biocompatible Materials Aquatic Organisms Adhesives Invertebrates Inspiration for innovation in healthcare regularly comes from observing the natural environment. Secreted adhesives are important for marine invertebrate attachment to submerged surfaces, and these systems have inspired investigations for better performing surgical adhesives. Natural marine adhesives are fundamentally proteins, therefore, most materials research has focused on the structure and function of proteinaceous components. Omics technologies have been used to identify proteins, but these candidates require further exploration to resolve function. Functional characterization begins by producing one specific protein in larger quantities with recombinant DNA technology. Recombinant proteins (RPs) are generally seen as mimics of individual marine adhesive proteins, representing a fundamental step in the development of bio-inspired glues. The literature details production of RPs from mussels, scallops, barnacles, tubeworms, ascidians, sea anemones, and sea stars, using bacteria, yeast, or insect and mammalian cells. Whole proteins, or components thereof, have been produced comprising the relevant amino acid sequences required for adhesion and have been investigated for use in healthcare via the production of materials that push the current limits of bio-inspired design. This is a thorough review of invertebrate marine adhesives investigated using biomimetic RPs, and a comprehensive overview of the innovative biomaterials designed utilizing knowledge from biological systems. |
| format | Artículo científico |
| id | pubmed_41039753 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Advanced healthcare materials |
| record_format | pubmed |
| spellingShingle | Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials. Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick Animals Recombinant Proteins Biocompatible Materials Aquatic Organisms Adhesives Invertebrates Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials. Whaite, Alessandra Duthoo, Emilie Lefevre, Mathilde Hennebert, Elise Flammang, Patrick Animals Recombinant Proteins Biocompatible Materials Aquatic Organisms Adhesives Invertebrates Inspiration for innovation in healthcare regularly comes from observing the natural environment. Secreted adhesives are important for marine invertebrate attachment to submerged surfaces, and these systems have inspired investigations for better performing surgical adhesives. Natural marine adhesives are fundamentally proteins, therefore, most materials research has focused on the structure and function of proteinaceous components. Omics technologies have been used to identify proteins, but these candidates require further exploration to resolve function. Functional characterization begins by producing one specific protein in larger quantities with recombinant DNA technology. Recombinant proteins (RPs) are generally seen as mimics of individual marine adhesive proteins, representing a fundamental step in the development of bio-inspired glues. The literature details production of RPs from mussels, scallops, barnacles, tubeworms, ascidians, sea anemones, and sea stars, using bacteria, yeast, or insect and mammalian cells. Whole proteins, or components thereof, have been produced comprising the relevant amino acid sequences required for adhesion and have been investigated for use in healthcare via the production of materials that push the current limits of bio-inspired design. This is a thorough review of invertebrate marine adhesives investigated using biomimetic RPs, and a comprehensive overview of the innovative biomaterials designed utilizing knowledge from biological systems. |
| title | Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials. |
| topic | Animals Recombinant Proteins Biocompatible Materials Aquatic Organisms Adhesives Invertebrates |
| url | https://pubmed.ncbi.nlm.nih.gov/41039753/ |