FL496, an FL118-derived small molecule, induces growth inhibition, senescence, and apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrexed-cisplatin combination.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Aljahdali, Ieman A M, Ling, Xiang, Wu, Wenjie, Wang, Wenchao, Li, Dan, Zhang, Renyuan, Zhang, Emma, Stablewski, Aimee, Azrak, Rami, Li, Qingyong, Li, Fengzhi
Format:	Artículo científico
Language:	en
Published:	Journal of experimental & clinical cancer research : CR 2025
Subjects:	Humans Pemetrexed Animals Mesothelioma, Malignant Mice Apoptosis Cisplatin Cellular Senescence Cell Line, Tumor Xenograft Model Antitumor Assays Pleural Neoplasms Antineoplastic Combined Chemotherapy Protocols Cell Proliferation Mice, SCID Mesothelioma Lung Neoplasms Disease Models, Animal
Online Access:	Acceder al recurso
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