Discovery of novel thiosemicarbazone dimers as effective inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1) for use in cancer therapy.

Fuente: PubMed

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Bibliographic Details
Main Authors:	Wang, Lijun, Wang, Yinghan, Guo, Shuju, Jiang, Bo, Guo, Chuanlong, Wang, Guangce
Format:	Artículo científico
Language:	en
Published:	European journal of medicinal chemistry 2026
Subjects:	Humans Thiosemicarbazones Poly (ADP-Ribose) Polymerase-1 Antineoplastic Agents Poly(ADP-ribose) Polymerase Inhibitors Animals Cell Proliferation Structure-Activity Relationship Drug Screening Assays, Antitumor Mice Molecular Structure Dose-Response Relationship, Drug Drug Discovery Female Cell Line, Tumor Dimerization Apoptosis Mice, Nude
Online Access:	Acceder al recurso
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