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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Comparative biochemistry and physiology. Part D, Genomics & proteomics
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41175669/ |
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| _version_ | 1868266132940521472 |
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| author | Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng |
| author_facet | Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng |
| collection | PubMed - marine biology |
| contents | Genome-wide identification and characterization of the HSP gene superfamily in the Ivory Shell (Babylonia areolata). Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng Animals Phylogeny Heat-Shock Proteins Multigene Family Gastropoda Heat-Shock Response Genome Heat shock proteins (HSPs) are highly conserved molecular chaperones that play essential roles in biological growth, development, and responses to environmental stress. To investigate the functions of HSPs in Babylonia areolata (BaHsps) under heat stress, a total of 68 BaHsp genes were identified at the genome-wide level using bioinformatics approaches. The phylogenetic tree, gene structure, chromosome location and protein physicochemical properties were predicted, and the expression patterns of BaHsp genes in different tissues under heat stress were analyzed and characterized by Quantitative Real-time polymerase chain reaction method (qPCR). The results revealed significant variation in the number and arrangement of introns among different BaHsp genes, with introns unevenly distributed across 26 chromosomes. Gene duplication analysis indicated tandem duplication events in the BaHsp20, BaHsp40 and BaHsp90, suggesting that these events contributed to the expansion and functional diversification of the BaHsp gene families. RT-qPCR results demonstrated clear tissue-specific expression of BaHsp genes, with overall expression levels being relatively high in gill tissue. Under heat stress, expression of BaHsp genes in gill tissue increased with rising temperatures. Temporal expression analysis further showed that most genes were rapidly upregulated at the onset of heat stress, followed by a gradual decline, exhibiting a dynamic pattern of "increase-then-decrease". This study provides a fundamental reference for further investigations into the molecular mechanisms of HSP gene family response to heat stress in B. areolata. |
| format | Artículo científico |
| id | pubmed_41175669 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Comparative biochemistry and physiology. Part D, Genomics & proteomics |
| record_format | pubmed |
| spellingShingle | Genome-wide identification and characterization of the HSP gene superfamily in the Ivory Shell (Babylonia areolata). Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng Animals Phylogeny Heat-Shock Proteins Multigene Family Gastropoda Heat-Shock Response Genome Genome-wide identification and characterization of the HSP gene superfamily in the Ivory Shell (Babylonia areolata). Fu, Deng Wu, Yingyin Hong, Xin Zhu, Yanyun Luo, Querui Li, Guanyi Tian, Kun Zheng, Xing Liu, Chunsheng Wang, Shifeng Wang, Aiming Gu, Zhifeng Yu, Feng Animals Phylogeny Heat-Shock Proteins Multigene Family Gastropoda Heat-Shock Response Genome Heat shock proteins (HSPs) are highly conserved molecular chaperones that play essential roles in biological growth, development, and responses to environmental stress. To investigate the functions of HSPs in Babylonia areolata (BaHsps) under heat stress, a total of 68 BaHsp genes were identified at the genome-wide level using bioinformatics approaches. The phylogenetic tree, gene structure, chromosome location and protein physicochemical properties were predicted, and the expression patterns of BaHsp genes in different tissues under heat stress were analyzed and characterized by Quantitative Real-time polymerase chain reaction method (qPCR). The results revealed significant variation in the number and arrangement of introns among different BaHsp genes, with introns unevenly distributed across 26 chromosomes. Gene duplication analysis indicated tandem duplication events in the BaHsp20, BaHsp40 and BaHsp90, suggesting that these events contributed to the expansion and functional diversification of the BaHsp gene families. RT-qPCR results demonstrated clear tissue-specific expression of BaHsp genes, with overall expression levels being relatively high in gill tissue. Under heat stress, expression of BaHsp genes in gill tissue increased with rising temperatures. Temporal expression analysis further showed that most genes were rapidly upregulated at the onset of heat stress, followed by a gradual decline, exhibiting a dynamic pattern of "increase-then-decrease". This study provides a fundamental reference for further investigations into the molecular mechanisms of HSP gene family response to heat stress in B. areolata. |
| title | Genome-wide identification and characterization of the HSP gene superfamily in the Ivory Shell (Babylonia areolata). |
| topic | Animals Phylogeny Heat-Shock Proteins Multigene Family Gastropoda Heat-Shock Response Genome |
| url | https://pubmed.ncbi.nlm.nih.gov/41175669/ |