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| Autori principali: | , |
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| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Bioscience, biotechnology, and biochemistry
2026
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| Soggetti: | |
| Accesso online: | https://pubmed.ncbi.nlm.nih.gov/41206556/ |
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Sommario:
- Cultivation properties and cell morphology of the Euglena gracilis SM-ZK strain under fed-batch cultivation conditions. Fukuda, Mizuki Hayashi, Masahiro Euglena gracilis Batch Cell Culture Techniques Biomass Glucose Fermentation Glucans Euglena gracilis cells grown in the dark accumulate a β-1,3-glucan called paramylon, synthesized from organic carbon sources. Paramylon has potential applications as a raw material for bioplastics and nanofibers. Strain SM-ZK, a streptomycin-bleached mutant of E. gracilis, lacks chloroplasts permanently and accumulates more paramylon than the wild-type strain. However, data are limited on the fermentation characteristics of this mutant strain. This study compares the cultivation characteristics of E. gracilis strains Z (wild-type strain) and SM-ZK under fed-batch cultivation conditions. Strain SM-ZK showed significantly higher productivity in terms of both biomass yield and glucose consumption than strain Z. Moreover, strain SM-ZK cells appeared to be gradually enlarged during fed-batch cultivation compared with strain Z that grows in uniform sizes. These novel findings support the potential use of strain SM-ZK for industrial-scale production of paramylon.