Image de couverture de livre

DHA affects ISKNV-induced autophagy flux via the AMPK/mTOR/ULK1 and BECN1/SQSTM1 axes, limiting viral replication in fish cells.

Fuente: PubMed

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Chen, Kuang-Wen, Huang, Chien-Fu, Wu, Jen-Leih, Hong, Jiann-Ruey
Format:	Artículo científico
Langue:	en
Publié:	Fish & shellfish immunology 2026
Sujets:	Animals Autophagy Docosahexaenoic Acids Virus Replication Fish Diseases Cell Line Beclin-1 TOR Serine-Threonine Kinases Autophagy-Related Protein-1 Homolog Signal Transduction Fish Proteins
Accès en ligne:	Acceder al recurso
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

Grass carp reovirus VP6 inhibits IFN production by degrading TBK1 through the autophagy pathway.
par: Xu, Xiao, et autres
Publié: (2025)

Computational Analysis of Azole Derivatives Targeting the PI3K/AKT/mTOR Pathway With In Vitro Cytotoxicity and Autophagy Evaluation.
par: Regurajan, Rathika, et autres
Publié: (2026)

Rewiring mTOR signaling in Alzheimer's disease: emerging mTOR modulators beyond oncology.
par: Lohnes, Benedikt Jakob, et autres
Publié: (2026)

Fish TOLLIP manipulates ATG5 for autophagic degradation of STING to attenuate antiviral interferon responses.
par: Tian, Meng-Ze, et autres
Publié: (2025)

RAPTOR-mediated autophagy promotes the accumulation of lipid and terpenoids in Schizochytrium sp. HX-308.
par: Yan, Chunxiao, et autres
Publié: (2026)

Fish CDK2 recruits Dtx4 to degrade TBK1 through ubiquitination in the antiviral response.
par: Lu, Long-Feng, et autres
Publié: (2026)

BIK1 and ATL31/6 are essential for fucoidan hydrolysate-triggered stomatal closure in Arabidopsis.
par: Chen, Kexin, et autres
Publié: (2025)

Diphenyl Disulfide Exerts Dual Cytotoxic Effects by Inducing Ferroptosis and Apoptosis in Melanoma Cells.
par: Chen, Sheng-Yuan, et autres
Publié: (2026)

Primary Cilia-Mediated Hedgehog Signaling Regulates Cell Fate During ER Stress-Induced Life or Death Decisions.
par: Xu, Jia, et autres
Publié: (2025)

Evolutionary analysis and immune-induced expression and mA modification of RIPK1 and RIPK2 in the miiuy croaker.
par: Xing, Qianru, et autres
Publié: (2025)

Hijacking of host Src-PI3K-Akt signaling by WSSV IE1 protein suppresses apoptotic and autophagic defenses to facilitate viral proliferation.
par: Lu, Kaiyu, et autres
Publié: (2026)

pacsin1 inhibits antiviral immunity by promoting MITA degradation through autophagy in miiuy croaker, Miichthysmiiuy.
par: Li, Wenxin, et autres
Publié: (2025)

SVCV phosphoprotein hijacks phase separation to immobilize the IRF3-TBK1 signaling axis and suppress interferon antiviral immunity.
par: Wang, Yueyi, et autres
Publié: (2026)

Grass carp reovirus VP4 manipulates TOLLIP to degrade STING for inhibition of IFN production.
par: Wang, Yang-Yang, et autres
Publié: (2025)

Activation of prep expression by Tet2 promotes the proliferation of bipotential progenitor cells during liver regeneration.
par: Jia, Kun, et autres
Publié: (2025)

Sex-Specific Lifespan Extension and Anti-Obesogenic Effects of Extract Through Tor Signaling Modulation in .
par: Tahan Zadeh, Navid, et autres
Publié: (2025)

Hippo-YAP pathway regulates antimicrobial immune response in obscure puffer Takifugu obscurus.
par: Wang, Ruixia, et autres
Publié: (2025)

Elucidation of anti-human melanoma and anti-aging mechanisms of compounds from green seaweed Caulerpa racemosa.
par: Wicaksono, Danar, et autres
Publié: (2024)

Autophagic degradation of MAVS-B by Carassius auratus herpesvirus (CaHV) ORF56 suppresses interferon response in polyploid gibel carp.
par: Zhou, Chu-Jing, et autres
Publié: (2026)

A nutrient-responsive AMPK/TBK1 circuit restricts adipocyte catabolism.
par: Wisessaowapak, Churaibhon, et autres
Publié: (2026)

Phosphoethanolamine cytidylyltransferase 2 integrates DAG metabolism and TBK1 activation to regulate antiviral innate immunity.
par: Lai, Wencong, et autres
Publié: (2026)

In vitro cytotoxic and pro-apoptotic effects of Chaetoceros socialis ethanolic extract on prostate (LNCap) and glioblastoma (U-87 MG) cells via modulation of AKT/PTEN, mTOR, BAX/BCL2, and Caspase pathways.
par: Asoudeh-Fard, Abbas, et autres
Publié: (2025)

Lipid Droplet Degradation Through Lipophagy in Aurantiochytrium limacinum mh0186.
par: Wu, Sheng, et autres
Publié: (2025)

Grouper deubiquitinating enzyme ovarian tumor domain-containing protein 5 (OTUD5) stabilizes stimulator of interferon genes (STING) via the autophagy-lysosomal pathway to modulate antiviral innate immunity in fish.
par: Wu, Siting, et autres
Publié: (2026)

Chryxanthone A, an extracted substance from endophytic fungal Aspergillus versicolor, produces anti-oxidant neuroprotection possibly via the action on mTOR/CREB axis.
par: Zhang, Xinyu, et autres
Publié: (2025)

Mechanistic Modulation of Autophagy by Bioactive Natural Products: Implications for Human Aging and Longevity.
par: Jalouli, Maroua, et autres
Publié: (2026)

Identification of novel CLK1 inhibitors by computational fragment-based ligand design, co-crystallization, chemical synthesis and structure activity relationships.
par: Bourg, Stéphane, et autres
Publié: (2026)

The novel marine factor 3,5-dihydroxy-4-methoxybenzyl alcohol exhibits anticancer activity by regulating multiple signaling pathways in human glioblastoma cells: Blocking EGF signaling.
par: Yamaguchi, Masayoshi, et autres
Publié: (2025)

Zebrafish TRIM2a promotes virus replication via ubiquitination of IRF3 and autophagic cargo receptor p62.
par: Huang, Wenji, et autres
Publié: (2025)

Identification of Marine Compounds Inhibiting NF-κBInducing Kinase Through Molecular Docking and Molecular Dynamics Simulations.
par: Yasir, Muhammad, et autres
Publié: (2024)

Aglaia elliptifolia Leaf Extract Inhibits Autophagy-Related 4B Protease and Suppresses Malignancies of Colorectal Cancer Cells.
par: Weng, Jing-Ru, et autres
Publié: (2025)

Synthesis and biological activity of 1H-pyrrolo[3,2-g]isoquinolines as Haspin kinase inhibitors.
par: Malosse, Killian, et autres
Publié: (2025)

Epicoccin A Ameliorates PD-like Symptoms in Zebrafish: Enhancement of PINK1/Parkin-Dependent Mitophagy and Inhibition of Excessive Oxidative Stress.
par: Ye, Haicheng, et autres
Publié: (2025)

plecoglossicida infection induces neutrophil autophagy-driven NETosis in large yellow croaker .
par: Cao, Jia-Feng, et autres
Publié: (2024)

Citrulline regulates macrophage metabolism and inflammation to counter aging in mice.
par: Xie, Zhangdan, et autres
Publié: (2025)

β-defensin 2 enhances antiviral immunity via autophagy regulation during Micropterus salmoides rhabdovirus (MSRV) infection and promotes survival in largemouth bass.
par: Zhu, Yong-Fei, et autres
Publié: (2026)

Zebrafish fkbp5 attenuates antiviral innate immunity by autophagic degradation of transcription factor irf7.
par: Wang, Yanyi, et autres
Publié: (2025)

RNF34 negatively regulates innate immunity via ubiquitin-mediated TAK1 degradation in miiuy croaker (Miichthysmiiuy).
par: Dong, Wenjing, et autres
Publié: (2025)

Data-Independent Acquisition-Based Quantitative Proteomics, Nontargeted Metabolomics, and Protein-Ligand Interaction Reveal the Mechanism of Baicalin Inhibiting βhemolytic/cytolytic Activities of .
par: Li, Guihua, et autres
Publié: (2026)

Oligo fucoidan alleviates sarcopenia via attenuating muscle mass loss and function decline in senescence-accelerated mouse prone 8 mice.
par: Chang, Yun-Ching, et autres
Publié: (2025)