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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Virology
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41365245/ |
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Table of Contents:
- Novel circoviruses identified in short-finned pilot whale and orca from the North Atlantic Ocean. De Koch, Matthew D Kraberger, Simona Fielding, Russell Smith, Kendal Schiavone, Kelsie Hall, Katharine R Reid, Vincent S Boyea, Diallo Smith, Emma L Schmidlin, Kara Fontenele, Rafaela S Martin, Darren P Krupovic, Mart Varsani, Arvind Animals Circovirus Atlantic Ocean Genome, Viral Phylogeny Whales, Pilot Circoviridae Infections High-Throughput Nucleotide Sequencing The family Circoviridae comprises viruses with small single-stranded DNA genomes that are known to infect various animals, resulting in considerable morbidity and mortality in some hosts. Circoviruses have been recently identified through metagenomic sequencing in diverse terrestrial vertebrate species, but their distribution and diversity in marine vertebrates remains underexplored. Here, we use high-throughput sequencing (HTS) to identify circoviruses from archived tissue samples of delphinids (order Artiodactyla, infraorder Cetacea, family Delphinidae). Based on the HTS data, we designed specific abutting primer pairs to recover seven complete circovirus genomes from individual delphinid hosts, namely, the short-finned pilot whale (Globicephala macrorhynchus, n = 5) and the orca (Orcinus orca, n = 2). The circoviruses from the two delphinid species share