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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artículo científico |
| Language: | en |
| Published: |
Nature plants
2026
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| Subjects: | |
| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41495459/ |
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| author | Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray |
| author_facet | Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray |
| collection | PubMed - marine biology |
| contents | Rapid local and systemic jasmonate signalling drives the initiation and establishment of plant systemic immunity. Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray Cyclopentanes Oxylipins Plant Immunity Signal Transduction Arabidopsis Pseudomonas syringae Arabidopsis Proteins Plant Diseases Plant Leaves Disease Resistance Nuclear Proteins Successful recognition of pathogen effectors by plant disease resistance proteins, or effector-triggered immunity (ETI), contains the invading pathogen through localized hypersensitive cell death. ETI also activates long-range signalling to establish broad-spectrum systemic acquired resistance (SAR). Here we describe a sensitive luciferase (LUC) reporter that captures the spatial-temporal dynamics of SAR signal generation, propagation and establishment in systemic responding leaves following ETI. JASMONATE-INDUCED SYSTEMIC SIGNAL 1 (JISS1) encodes an endoplasmic-reticulum-localized protein of unknown function. JISS1::LUC captured very early ETI-elicited SAR signalling, which surprisingly was not affected by classical SAR mutants but was dependent on calcium and was also wound responsive. Both jasmonate biosynthesis and perception mutants abolished JISS1::LUC signalling and SAR to Pseudomonas syringae. Furthermore, we discovered that ETI initiated jasmonate-dependent systemic surface electrical potentials. These surface potentials were dependent on both glutamate receptors and JISS1, despite neither JISS1 loss-of-function nor glutamate receptor mutants altering SAR to Pseudomonas syringae. We thus demonstrate that jasmonate signalling, usually associated with antagonism of defence against biotrophs, is crucial to the rapid initiation and establishment of SAR systemic defence responses (including the activation of systemic surface potentials) and that JISS1::LUC serves as a reporter to further dissect these pathways. |
| format | Artículo científico |
| id | pubmed_41495459 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | Nature plants |
| record_format | pubmed |
| spellingShingle | Rapid local and systemic jasmonate signalling drives the initiation and establishment of plant systemic immunity. Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray Cyclopentanes Oxylipins Plant Immunity Signal Transduction Arabidopsis Pseudomonas syringae Arabidopsis Proteins Plant Diseases Plant Leaves Disease Resistance Nuclear Proteins Rapid local and systemic jasmonate signalling drives the initiation and establishment of plant systemic immunity. Gaikwad, Trupti Breen, Susan Breeze, Emily Stroud, Erin Hussain, Rana Kulasekaran, Satish Kargios, Nestoras Bennett, Fay de Torres-Zabala, Marta Horsell, David Frigerio, Lorenzo Kachroo, Pradeep Grant, Murray Cyclopentanes Oxylipins Plant Immunity Signal Transduction Arabidopsis Pseudomonas syringae Arabidopsis Proteins Plant Diseases Plant Leaves Disease Resistance Nuclear Proteins Successful recognition of pathogen effectors by plant disease resistance proteins, or effector-triggered immunity (ETI), contains the invading pathogen through localized hypersensitive cell death. ETI also activates long-range signalling to establish broad-spectrum systemic acquired resistance (SAR). Here we describe a sensitive luciferase (LUC) reporter that captures the spatial-temporal dynamics of SAR signal generation, propagation and establishment in systemic responding leaves following ETI. JASMONATE-INDUCED SYSTEMIC SIGNAL 1 (JISS1) encodes an endoplasmic-reticulum-localized protein of unknown function. JISS1::LUC captured very early ETI-elicited SAR signalling, which surprisingly was not affected by classical SAR mutants but was dependent on calcium and was also wound responsive. Both jasmonate biosynthesis and perception mutants abolished JISS1::LUC signalling and SAR to Pseudomonas syringae. Furthermore, we discovered that ETI initiated jasmonate-dependent systemic surface electrical potentials. These surface potentials were dependent on both glutamate receptors and JISS1, despite neither JISS1 loss-of-function nor glutamate receptor mutants altering SAR to Pseudomonas syringae. We thus demonstrate that jasmonate signalling, usually associated with antagonism of defence against biotrophs, is crucial to the rapid initiation and establishment of SAR systemic defence responses (including the activation of systemic surface potentials) and that JISS1::LUC serves as a reporter to further dissect these pathways. |
| title | Rapid local and systemic jasmonate signalling drives the initiation and establishment of plant systemic immunity. |
| topic | Cyclopentanes Oxylipins Plant Immunity Signal Transduction Arabidopsis Pseudomonas syringae Arabidopsis Proteins Plant Diseases Plant Leaves Disease Resistance Nuclear Proteins |
| url | https://pubmed.ncbi.nlm.nih.gov/41495459/ |