Strategic approaches to the discovery of biologically active indole derivatives: a comprehensive review.
Fuente:
PubMed
Saved in:
| Main Authors: | Gao, Gui-Ping, Li, Quan-Ke, Ma, Jin-Cheng, Zhang, Zhi-Jun, Zhang, Shao-Yong, Liu, Ying-Qian |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Bioorganic & medicinal chemistry
2026
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Unveiling a pyrroloindoline diketopiperazine biosynthetic pathway featuring a phytoene-synthase-like family prenyltransferase with distinct regioselectivity.
by: Duan, He, et al.
Published: (2025)
by: Duan, He, et al.
Published: (2025)
Genome mining of nonenzymatic ortho-quinone methide-based pseudonatural products from ascidian-derived fungus Diaporthe sp.SYSU-MS4722.
by: Ren, Shuya, et al.
Published: (2025)
by: Ren, Shuya, et al.
Published: (2025)
The Chemistry and Biology of the Tetrodotoxin Natural Product Family.
by: Nißl, Benedikt, et al.
Published: (2025)
by: Nißl, Benedikt, et al.
Published: (2025)
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
by: Chen, Xiaohui, et al.
Published: (2025)
by: Chen, Xiaohui, et al.
Published: (2025)
Genome analysis-led discovery of antimicrobial and herbicidal cytochalasans from the cold-seep-sourced endozoic Curvularia verruculosa CS-129.
by: Hu, Xue-Yi, et al.
Published: (2026)
by: Hu, Xue-Yi, et al.
Published: (2026)
SMART-assisted discovery of scalaranes from the marine sponge Lendenfeldia sp. and its anti-osteoclastogenesis activity.
by: Pham, Quoc-Vu, et al.
Published: (2026)
by: Pham, Quoc-Vu, et al.
Published: (2026)
Structure, biological activity, and biosynthesis of natural chromanes and chromenes.
by: Liu, Ying, et al.
Published: (2025)
by: Liu, Ying, et al.
Published: (2025)
Sirenin and bisabolane sesquiterpenoids from two marine isolates of Penicillium chermesinum with anti-osteoporotic activity by modulating NOD-like receptor signaling pathway.
by: Liu, Yi-Wei, et al.
Published: (2025)
by: Liu, Yi-Wei, et al.
Published: (2025)
Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues.
by: George, Malcolm R P, et al.
Published: (2026)
by: George, Malcolm R P, et al.
Published: (2026)
Ircindrimanes A-I, nine undescribed meroterpenoids with cytotoxic activities from the marine sponge Ircinia sp.
by: Zhang, Wenjie, et al.
Published: (2025)
by: Zhang, Wenjie, et al.
Published: (2025)
Stereoselective AChE/BChE/BACE1 inhibition by enantiomeric norsesquiterpenoids with an unprecedented oxatricyclo[7.2.1.0]dodecane scaffold from the soft coral Sclerophytum humesi.
by: Luu, Phuong Vu, et al.
Published: (2026)
by: Luu, Phuong Vu, et al.
Published: (2026)
The evolving chemistry of cADPR analogues: from marine discovery to calcium signaling tools.
by: Falanga, Andrea Patrizia, et al.
Published: (2025)
by: Falanga, Andrea Patrizia, et al.
Published: (2025)
Phyllofolactones V-X, Bishomoscalaranes With Proangiogenic and Hypolipidemic Activities From Sponge Phyllospongia foliascens.
by: Hu, Bo, et al.
Published: (2025)
by: Hu, Bo, et al.
Published: (2025)
Design, Synthesis, and Antibacterial Activity of Long-Chain Alkyl-Substituted DemethyloxyAaptamine Derivatives.
by: Liu, Yingqiu, et al.
Published: (2025)
by: Liu, Yingqiu, et al.
Published: (2025)
Sclerohumins G-L: Selective cytotoxic diterpenoids featuring a 4/9-fused ring system from the soft coral Sclerophytum humesi.
by: Luu, Phuong Vu, et al.
Published: (2026)
by: Luu, Phuong Vu, et al.
Published: (2026)
Discovery of novel ten-membered lactones as osteoblastogenesis agents targeting Wnt/β-catenin signaling pathway.
by: Zhai, Yi-Jie, et al.
Published: (2026)
by: Zhai, Yi-Jie, et al.
Published: (2026)
Beauvericin promotes autophagy and mitophagy by activating NIPSNAP2.
by: Zhao, Xue, et al.
Published: (2026)
by: Zhao, Xue, et al.
Published: (2026)
Discovery of therapeutic promising natural products to target Kv1.3 channel, a transmembrane protein regulating immune disorders, through multidimensional virtual screening, molecular dynamics simulations and biological validation.
by: Zhang, Shanshan, et al.
Published: (2025)
by: Zhang, Shanshan, et al.
Published: (2025)
New Phthalide Derivatives With Cardioprotective Effects From the Marine Fungus Diaporthe phaseolorum HZ-2.
by: Feng, Ran-Qi, et al.
Published: (2026)
by: Feng, Ran-Qi, et al.
Published: (2026)
Marine-Derived Compounds: A New Horizon in Cancer, Renal, and Metabolic Disease Therapeutics.
by: Zhang, Jinwei
Published: (2025)
by: Zhang, Jinwei
Published: (2025)
Discovery of an Indole-Quinazoline Alkaloid as an Anti-kidney Fibrotic Agent from the Marine-Derived SCSIO 41444.
by: She, Jianglian, et al.
Published: (2026)
by: She, Jianglian, et al.
Published: (2026)
Recent advance in macrolactams: Structure, bioactivity, and biosynthesis.
by: Qiu, Jiawei, et al.
Published: (2025)
by: Qiu, Jiawei, et al.
Published: (2025)
Disulfide-bonded YC18: A membrane-targeting peptide with superior efficacy against Staphylococcus aureus infections.
by: Gao, Jinai, et al.
Published: (2026)
by: Gao, Jinai, et al.
Published: (2026)
Cacomalides A-G, Manoalide-Related Sesterterpenes With Anti-Inflammatory Activities From the Marine Sponge Cacosponges sp.
by: Zhang, Wenjie, et al.
Published: (2025)
by: Zhang, Wenjie, et al.
Published: (2025)
Talaroindiones A-C, New Polyketides Characterized From the Cold-Seep-Derived Talaromyces indigoticus CS-469.
by: Deng, Ruo-Xi, et al.
Published: (2026)
by: Deng, Ruo-Xi, et al.
Published: (2026)
A Cinderella story in antimicrobials: CDPDP's perfect fit for multiple-pathway bacterial inhibition.
by: Ul Hassan, Syed Shams, et al.
Published: (2025)
by: Ul Hassan, Syed Shams, et al.
Published: (2025)
Oxidative Electrocyclization Assembles 2,2-Dimethyl-2H-pyran in Fungal Indole Alkaloids.
by: Zhang, Chengjie, et al.
Published: (2025)
by: Zhang, Chengjie, et al.
Published: (2025)
Selective Synthesis of Cyclopeptides with a 2-Oxindole or 3a-Hydroxy-hexahydropyrrolo-[2,3-]indole Structure by Cytochrome P450 Enzymes.
by: Li, Chao, et al.
Published: (2025)
by: Li, Chao, et al.
Published: (2025)
Mucoadhesive lignin-liposome nanocarriers of coptisine: A multifunctional strategy against antibiotic-resistant Helicobacter pylori biofilms.
by: Sharaf, Mohamed, et al.
Published: (2026)
by: Sharaf, Mohamed, et al.
Published: (2026)
Identification of novel CLK1 inhibitors by computational fragment-based ligand design, co-crystallization, chemical synthesis and structure activity relationships.
by: Bourg, Stéphane, et al.
Published: (2026)
by: Bourg, Stéphane, et al.
Published: (2026)
Oxalicpyridones A-D, 2-pyridone alkaloids from a marine-derived fungus Penicillium oxalicum suppressing proliferation and metastasis against small cell lung cancer.
by: Chen, Xiangliu, et al.
Published: (2026)
by: Chen, Xiangliu, et al.
Published: (2026)
Optimized ebselen derivatives as novel potent Escherichia coli β-glucuronidase covalent allosteric inhibitors.
by: Ying, Ti-Ti, et al.
Published: (2025)
by: Ying, Ti-Ti, et al.
Published: (2025)
Development of molecular Trojan horses targeting New Delhi metallo-β-lactamase-1 for the restoration of meropenem susceptibility in drug-resistant bacteria.
by: Liu, Wandong, et al.
Published: (2025)
by: Liu, Wandong, et al.
Published: (2025)
Preparation of mitochondria-targeted camptothecin derivatives for the imaging and antiproliferation of colorectal cancer.
by: Xu, Chenmeng, et al.
Published: (2025)
by: Xu, Chenmeng, et al.
Published: (2025)
LL-37-derived peptide shows promising antimicrobial potential against multidrug-resistance pathogens.
by: Asmamaw, Demeke, et al.
Published: (2026)
by: Asmamaw, Demeke, et al.
Published: (2026)
Cytotoxicity, apoptosis, molecular docking, and molecular dynamics study of novel compounds of Sulfamide derivatives coupled with DHP scaffolds as potent inhibitors of the MCF-7, A549, SKOV-3, and EA. yh926 carcinoma cells.
by: Abdulrasool, Amjed, et al.
Published: (2026)
by: Abdulrasool, Amjed, et al.
Published: (2026)
Revelation of Brevi-inflammin, a novel anti-inflammatory metabolite from Brevibacterium casei VRK 1, as a potent COX-2 inhibitor.
by: Chandrasekaran, Vishnupriya, et al.
Published: (2025)
by: Chandrasekaran, Vishnupriya, et al.
Published: (2025)
9H-carbazole derivatives from a Streptomyces species under potassium iodide stress and their anti-inflammatory properties.
by: Yan, Pengcheng, et al.
Published: (2025)
by: Yan, Pengcheng, et al.
Published: (2025)
Placidenes G-J, Bioactive γ-Pyrone Derivatives From the Marine Mollusk Placida dendritica.
by: Wang, Hao, et al.
Published: (2026)
by: Wang, Hao, et al.
Published: (2026)
Progress in the discovery and development of anticancer agents from marine cyanobacteria.
by: Luesch, Hendrik, et al.
Published: (2025)
by: Luesch, Hendrik, et al.
Published: (2025)
Similar Items
-
Unveiling a pyrroloindoline diketopiperazine biosynthetic pathway featuring a phytoene-synthase-like family prenyltransferase with distinct regioselectivity.
by: Duan, He, et al.
Published: (2025) -
Genome mining of nonenzymatic ortho-quinone methide-based pseudonatural products from ascidian-derived fungus Diaporthe sp.SYSU-MS4722.
by: Ren, Shuya, et al.
Published: (2025) -
The Chemistry and Biology of the Tetrodotoxin Natural Product Family.
by: Nißl, Benedikt, et al.
Published: (2025) -
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment.
by: Chen, Xiaohui, et al.
Published: (2025) -
Genome analysis-led discovery of antimicrobial and herbicidal cytochalasans from the cold-seep-sourced endozoic Curvularia verruculosa CS-129.
by: Hu, Xue-Yi, et al.
Published: (2026)