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| Format: | Artículo científico |
| Language: | en |
| Published: |
bioRxiv : the preprint server for biology
2026
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| Online Access: | https://pubmed.ncbi.nlm.nih.gov/41659575/ |
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| _version_ | 1868266087584366592 |
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| author | Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C |
| author_facet | Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C |
| collection | PubMed - marine biology |
| contents | Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data. Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C Microbial metabolites play a critical role in regulating ecosystems, including the human body and its microbiota. However, understanding the physiologically relevant role of these molecules, especially through liquid chromatography tandem mass spectrometry (LC-MS/MS)-based untargeted metabolomics, poses significant challenges and often requires manual parsing of a large amount of literature, databases, and webpages. To address this gap, we established the Collaborative Microbial Metabolite Center knowledgebase (CMMC-KB), a platform that fosters collaborative efforts within the scientific community to curate knowledge about microbial metabolites. The CMMC-KB aims to collect comprehensive information about microbial molecules originating from microbial biosynthesis, drug metabolism, exposure-related molecules, food, host-derived molecules, and, whenever available, their known activities. Molecules from other sources, including host-produced, dietary, and pharmaceutical compounds, are also included. By enabling direct integration of this knowledgebase with downstream analytical tools, including molecular networking, we can deepen insights into microbiota and their metabolites, ultimately advancing our understanding of microbial ecosystems. |
| format | Artículo científico |
| id | pubmed_41659575 |
| institution | PubMed |
| language | en |
| publishDate | 2026 |
| publisher | bioRxiv : the preprint server for biology |
| record_format | pubmed |
| spellingShingle | Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data. Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data. Mannochio-Russo, Helena Gonçalves Nunes, Wilhan D Xing, Shipei de Oliveira, Fernanda Caraballo-Rodríguez, Andrés Mauricio Gomes, Paulo Wender Portal Charron-Lamoureux, Vincent Agongo, Julius Avalon, Nicole E Bui, Tammy Cancelada, Lucia Chevrette, Marc G Cumsille, Andrés de Araújo, Moysés B De Graeve, Marilyn Deleray, Victoria Donia, Mohamed S Dzveta, Mutsawashe B El Abiead, Yasin Ellis, Ronald J Franklin, Donald Garg, Neha Gouda, Harsha Djande, Claude Y Hamany Hiskia, Anastasia Ho, Benjamin N Hughes, Chambers C Hwang, Sunghoon Iliakopoulou, Sofia Iudicello, Jennifer E Jarmusch, Alan K Kaloudis, Triantafyllos Koester, Irina Konkel, Robert Koolen, Hector H F Kvitne, Kine Eide La Rosa, Sabina Leanti Lam, Anny Lamichhane, Santosh Lephatsi, Motseoa Letendre, Scott Magyari, Sarolt Mazur-Marzec, Hanna McDonald, Daniel Mohanty, Ipsita Monge-Loría, Mónica Moore, David J Veiga, Thiago André Moura Mulaudzi, Musiwalo S Nephali, Lerato Nguyen, Griffith Orságh, Martin Patan, Abubaker Pluskal, Tomáš Pope, Phillip B de Medeiros, Lívia Soman Stincone, Paolo Tekel, Andrej Thomas, Sydney Torres, Ralph R Tsunoda, Shirley M Tugizimana, Fidele van Faassen, Martijn Vasquez-Castro, Felipe Vitale, Giovanni A Wagner, Berenike C Wang, Crystal X Zervou, Sevasti-Kiriaki Zhao, Haoqi Nina Zuffa, Simone Petras, Daniel McCall, Laura-Isobel Knight, Rob Wang, Mingxun Dorrestein, Pieter C Microbial metabolites play a critical role in regulating ecosystems, including the human body and its microbiota. However, understanding the physiologically relevant role of these molecules, especially through liquid chromatography tandem mass spectrometry (LC-MS/MS)-based untargeted metabolomics, poses significant challenges and often requires manual parsing of a large amount of literature, databases, and webpages. To address this gap, we established the Collaborative Microbial Metabolite Center knowledgebase (CMMC-KB), a platform that fosters collaborative efforts within the scientific community to curate knowledge about microbial metabolites. The CMMC-KB aims to collect comprehensive information about microbial molecules originating from microbial biosynthesis, drug metabolism, exposure-related molecules, food, host-derived molecules, and, whenever available, their known activities. Molecules from other sources, including host-produced, dietary, and pharmaceutical compounds, are also included. By enabling direct integration of this knowledgebase with downstream analytical tools, including molecular networking, we can deepen insights into microbiota and their metabolites, ultimately advancing our understanding of microbial ecosystems. |
| title | Community Curation of Microbial Metabolites Enables Biological Insights of Metabolomics Data. |
| url | https://pubmed.ncbi.nlm.nih.gov/41659575/ |